2-(Dicyclohexylphosphino)-2',4',6'-triisopropyl-3,6-dimethoxybiphenyl

Product Information

Molecular Formula:
C35H53O2P
Molecular Weight:
536.77
Description
Buchwald Phosphine Ligands for chemical Synthesis BrettPhos is a dialkylbiaryl phosphine ligand developed by the Buchwald group. It promotes cross-coupling reactions more efficiently and exhibits improved reactivity compared to other catalytic systems.It can be used in: palladium-catalyzed trifluoromethylation of aryl chlorides; Buchwald-Hartwig amination; synthesis of 4-aryl and alkyl substituted, N6-alkylated pyridazine-3,6-diamines via a Buchwald protocol.
Synonyms
dicyclohexyl-[3,6-dimethoxy-2-[2,4,6-tri(propan-2-yl)phenyl]phenyl]phosphine; dicyclohexyl-[3,6-dimethoxy-2-[2,4,6-tri(propan-2-yl)phenyl]phenyl]phosphane
IUPAC Name
dicyclohexyl-[3,6-dimethoxy-2-[2,4,6-tri(propan-2-yl)phenyl]phenyl]phosphane
Canonical SMILES
CC(C)C1=CC(=C(C(=C1)C(C)C)C2=C(C=CC(=C2P(C3CCCCC3)C4CCCCC4)OC)OC)C(C)C
InChI
InChI=1S/C35H53O2P/c1-23(2)26-21-29(24(3)4)33(30(22-26)25(5)6)34-31(36-7)19-20-32(37-8)35(34)38(27-15-11-9-12-16-27)28-17-13-10-14-18-28/h19-25,27-28H,9-18H2,1-8H3
InChI Key
WDVGNXKCFBOKDF-UHFFFAOYSA-N
Melting Point
187-195 °C
Flash Point
Not applicable
Purity
98 %
LogP
10.51360

Safety Information

Precautionary Statement
P261, P264, P270, P271, P273, P280, P301+P312, P302+P352, P304+P340, P305+P351+P338, P312, P321, P330, P332+P313, P337+P313, P362, P403+P233, P405, and P501
Signal Word
Warning

Computed Properties

XLogP3
10.1
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
2
Rotatable Bond Count
9
Exact Mass
536.37831793 g/mol
Monoisotopic Mass
536.37831793 g/mol
Topological Polar Surface Area
18.5Ų
Heavy Atom Count
38
Formal Charge
0
Complexity
643
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes

Patents

Publication Number Title Priority Date
CN-114085213-A Preparation method of ARV-471 2022-01-20
CN-114014850-A Prudelamine intermediate, synthesis method thereof and method for synthesizing prasulamine from intermediate 2021-12-17
CN-113816925-A A trematopsin 3 "-tert-butyl-4 '- (2-hydroxyethoxy) -4" -pyrrolidin-1-yl [1, 1'; process for preparing 3 ', 1' ] -terphenyl-4-carboxylic acid 2021-09-18
CN-113328092-A Aqueous all-organic secondary battery based on oxazine compounds with multiple oxidation states 2021-05-28
JP-2021066737-A Method for producing coupling compound 2021-01-19
CN-112552224-A Synthesis method of 4-hydroxyindole 2020-12-30
CN-113845478-A Intermediate, preparation method and application thereof 2020-12-18
CN-112300091-A Triazole heterocyclic compound and preparation method and application thereof 2020-11-25
JP-2021035987-A Pest control method 2020-11-16
JP-2021035988-A Plant pathogenic microorganism control composition and plant pathogenic microorganism control method 2020-11-16
The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Related Products

Online Inquiry
  • Verification code
USA
  • International:
  • US & Canada (Toll free):
  • Email:
  • Fax:
UK
  • Email:
Copyright © 2024 BOC Sciences. All rights reserved.
Top
Inquiry Basket