2-Dicyclohexylphosphino-2',6'-dimethoxybiphenyl

SPhos may be used as a ligand in the following processes: Palladium catalyzed Suzuki-Miyaura cross-coupling reaction between Boc-protected aminomethyltrifluoroborate and aryl chlorides or hetaryl chlorides to form the corresponding aminomethylarenes.; Palladium catalyzed Suzuki-Miyaura cross-coupling reaction between 4-methyl-substituted piperidinylzinc reagent and different aryl or heteroaryl iodides to form various substituted piperidines; Intramolecular Suzuki-Miyaura coupling to form the 18-membered macrocyclic ring during the multi-step synthesis of riccardin C. Utilized in conjunction with palladium to form a highly active catalyst for C-N bond formation. Highly universal ligand for Suzuki-Miyaura coupling; aryl chlorides, hindered biaryls, heterobiaryls.

dicyclohexyl-[2-(2,6-dimethoxyphenyl)phenyl]phosphine; dicyclohexyl-[2-(2,6-dimethoxyphenyl)phenyl]phosphane

dicyclohexyl-[2-(2,6-dimethoxyphenyl)phenyl]phosphane

COC1=C(C(=CC=C1)OC)C2=CC=CC=C2P(C3CCCCC3)C4CCCCC4

InChI=1S/C26H35O2P/c1-27-23-17-11-18-24(28-2)26(23)22-16-9-10-19-25(22)29(20-12-5-3-6-13-20)21-14-7-4-8-15-21/h9-11,16-21H,3-8,12-15H2,1-2H3

VNFWTIYUKDMAOP-UHFFFAOYSA-N

513.3 °C at 760 mmHg

164-166 °C (lit.)

Not applicable

98 %

7.14340

P261, P264, P270, P271, P272, P280, P301+P312, P302+P352, P304+P312, P304+P340, P305+P351+P338, P312, P321, P322, P330, P332+P313, P333+P313, P337+P313, P362, P363, P403+P233, P405, and P501

Warning