2-(Diphenylphosphino)pyridine

Product Information

Molecular Formula:
C17H14NP
Molecular Weight:
263.27
Description
Ligand for metal-catalyzed carbonylations, hydration, dehydrogenative coupling, carbostannylation, distannylation, and silylation; reagent for Mitsunobu reaction.
Synonyms
Diphenyl-2-pyridylphosphine; 37943-90-1; 2-(Diphenylphosphino)pyridine; 2-Pyridyldiphenylphosphine; diphenyl(2-pyridinyl)phosphine; 2-Diphenylphosphanyl-pyridine
IUPAC Name
diphenyl(pyridin-2-yl)phosphane
Canonical SMILES
C1=CC=C(C=C1)P(C2=CC=CC=C2)C3=CC=CC=N3
InChI
InChI=1S/C17H14NP/c1-3-9-15(10-4-1)19(16-11-5-2-6-12-16)17-13-7-8-14-18-17/h1-14H
InChI Key
SVABQOITNJTVNJ-UHFFFAOYSA-N
Boiling Point
377.5°C at 760 mmHg
Melting Point
82-84°C
Flash Point
Not applicable
Purity
95%
Solubility
10 [ug/mL] (The mean of the results at pH 7.4)
Appearance
yellow to orange crystalline powder

Safety Information

Hazards
H315 H319 H335 H413
Precautionary Statement
P261 P305+P351+P338

Computed Properties

XLogP3
3.9
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
1
Rotatable Bond Count
3
Exact Mass
263.086386449 g/mol
Monoisotopic Mass
263.086386449 g/mol
Topological Polar Surface Area
12.9Ų
Heavy Atom Count
19
Formal Charge
0
Complexity
238
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes

Patents

Publication Number Title Priority Date
CN-114011473-A Non-noble metal copper-based catalyst and application thereof in benzylamine oxidation coupling reaction 2021-11-30
CN-113980686-A Preparation method of cyclohexyl-containing lateral o-difluorobenzene liquid crystal compound 2021-10-25
CN-113698431-A Synthesis method of phosphine (III) compound 2021-09-27
CN-113816925-A A trematopsin 3 "-tert-butyl-4 '- (2-hydroxyethoxy) -4" -pyrrolidin-1-yl [1, 1'; process for preparing 3 ', 1' ] -terphenyl-4-carboxylic acid 2021-09-18
CN-113292534-A Preparation method of bilastine key intermediate 2021-05-27
CN-113278031-A Copper-based nanocluster, ionic liquid induced synthesis method and application 2021-05-21
CN-113224313-A Metal organic phosphine frame glass modified metal negative current collector and preparation method thereof 2021-04-30
CN-112570032-A Water-soluble hydroformylation catalyst and application thereof 2020-11-17
CN-114163771-A Resin composition 2020-09-11
CN-114163772-A Resin composition 2020-09-11

Literatures

PMID Publication Date Title Journal
21724304 2011-09-01 Synthesis, characterization and anticancer studies of mixed ligand dithiocarbamate palladium(II) complexes European journal of medicinal chemistry
21761070 2011-08-28 Methanol triggered ligand flip isomerization in a binuclear copper(I) complex and the luminescence response Chemical communications (Cambridge, England)
21553862 2011-06-01 Mixed phosphane η5-CpRuCl(PR3)2 complexes as ambifunctional catalysts for anti-Markovnikov hydration of terminal alkynes Journal of the American Chemical Society
21522558 2010-12-04 [N-Benzyl-N-(diphenyl-phosphanylmeth-yl)pyridin-2-amine]-chloridomethyl-platinum(II) Acta crystallographica. Section E, Structure reports online
20657926 2010-09-14 The synthesis of, and characterization of the dynamic processes occurring in Pd(II) chelate complexes of 2-pyridyldiphenylphosphine Dalton transactions (Cambridge, England : 2003)
20143791 2010-03-15 Cyclometalated cluster complex with a butterfly-shaped Pt2Ag2 core Inorganic chemistry
20162217 2010-03-07 Dichlorostannylene complexes of group 10 metals, a unique bonding mode stabilized by bridging 2-pyridyldiphenylphosphine ligands Dalton transactions (Cambridge, England : 2003)
19888762 2009-11-12 Identifying potent, selective protein tyrosine phosphatase inhibitors from a library of Au(I) complexes Journal of medicinal chemistry
19259574 2009-03-21 Synthesis and reactivity of homo- and hetero-dimetallic complexes bridged by diphenyl-2-pyridylphosphine and hydrides: regioselectivity of alkyne insertion into unsaturated M1(micro-PPh2Py)(micro-H)2M2 moieties Dalton transactions (Cambridge, England : 2003)
19053612 2009-01-02 Convenient syntheses of 3'-amino-2',3'-dideoxynucleosides, their 5'-monophosphates, and 3'-aminoterminal oligodeoxynucleotide primers The Journal of organic chemistry
The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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