2-(Diphenylphosphino)pyridine
Product Information
Molecular Formula
C17H14NP
Molecular Weight
263.27
Description
Ligand for metal-catalyzed carbonylations, hydration, dehydrogenative coupling, carbostannylation, distannylation, and silylation; reagent for Mitsunobu reaction.
Synonyms
Diphenyl-2-pyridylphosphine; 37943-90-1; 2-(Diphenylphosphino)pyridine; 2-Pyridyldiphenylphosphine; diphenyl(2-pyridinyl)phosphine; 2-Diphenylphosphanyl-pyridine
IUPAC Name
diphenyl(pyridin-2-yl)phosphane
SMILES
C1=CC=C(C=C1)P(C2=CC=CC=C2)C3=CC=CC=N3
InChI
InChI=1S/C17H14NP/c1-3-9-15(10-4-1)19(16-11-5-2-6-12-16)17-13-7-8-14-18-17/h1-14H
InChI Key
SVABQOITNJTVNJ-UHFFFAOYSA-N
Boiling Point
377.5°C at 760 mmHg
Melting Point
82-84°C
Flash Point
Not applicable
Purity
95%
Solubility
10 [ug/mL] (The mean of the results at pH 7.4)
Appearance
yellow to orange crystalline powder
Safety Information
Hazards
H315 H319 H335 H413
Precautionary Statement
P261 P305+P351+P338
Computed Properties
XLogP3
3.9
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
1
Rotatable Bond Count
3
Exact Mass
263.086386449 g/mol
Monoisotopic Mass
263.086386449 g/mol
Topological Polar Surface Area
12.9Ų
Heavy Atom Count
19
Formal Charge
0
Complexity
238
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| CN-114011473-A | Non-noble metal copper-based catalyst and application thereof in benzylamine oxidation coupling reaction | 2021-11-30 |
| CN-113980686-A | Preparation method of cyclohexyl-containing lateral o-difluorobenzene liquid crystal compound | 2021-10-25 |
| CN-113698431-A | Synthesis method of phosphine (III) compound | 2021-09-27 |
| CN-113816925-A | A trematopsin 3 "-tert-butyl-4 '- (2-hydroxyethoxy) -4" -pyrrolidin-1-yl [1, 1'; process for preparing 3 ', 1' ] -terphenyl-4-carboxylic acid | 2021-09-18 |
| CN-113292534-A | Preparation method of bilastine key intermediate | 2021-05-27 |
| CN-113278031-A | Copper-based nanocluster, ionic liquid induced synthesis method and application | 2021-05-21 |
| CN-113224313-A | Metal organic phosphine frame glass modified metal negative current collector and preparation method thereof | 2021-04-30 |
| CN-112570032-A | Water-soluble hydroformylation catalyst and application thereof | 2020-11-17 |
| CN-114163771-A | Resin composition | 2020-09-11 |
| CN-114163772-A | Resin composition | 2020-09-11 |
Literatures
| PMID | Publication Date | Title | Journal |
|---|---|---|---|
| 21724304 | 2011-09-01 | Synthesis, characterization and anticancer studies of mixed ligand dithiocarbamate palladium(II) complexes | European journal of medicinal chemistry |
| 21761070 | 2011-08-28 | Methanol triggered ligand flip isomerization in a binuclear copper(I) complex and the luminescence response | Chemical communications (Cambridge, England) |
| 21553862 | 2011-06-01 | Mixed phosphane η5-CpRuCl(PR3)2 complexes as ambifunctional catalysts for anti-Markovnikov hydration of terminal alkynes | Journal of the American Chemical Society |
| 21522558 | 2010-12-04 | [N-Benzyl-N-(diphenyl-phosphanylmeth-yl)pyridin-2-amine]-chloridomethyl-platinum(II) | Acta crystallographica. Section E, Structure reports online |
| 20657926 | 2010-09-14 | The synthesis of, and characterization of the dynamic processes occurring in Pd(II) chelate complexes of 2-pyridyldiphenylphosphine | Dalton transactions (Cambridge, England : 2003) |
| 20143791 | 2010-03-15 | Cyclometalated cluster complex with a butterfly-shaped Pt2Ag2 core | Inorganic chemistry |
| 20162217 | 2010-03-07 | Dichlorostannylene complexes of group 10 metals, a unique bonding mode stabilized by bridging 2-pyridyldiphenylphosphine ligands | Dalton transactions (Cambridge, England : 2003) |
| 19888762 | 2009-11-12 | Identifying potent, selective protein tyrosine phosphatase inhibitors from a library of Au(I) complexes | Journal of medicinal chemistry |
| 19259574 | 2009-03-21 | Synthesis and reactivity of homo- and hetero-dimetallic complexes bridged by diphenyl-2-pyridylphosphine and hydrides: regioselectivity of alkyne insertion into unsaturated M1(micro-PPh2Py)(micro-H)2M2 moieties | Dalton transactions (Cambridge, England : 2003) |
| 19053612 | 2009-01-02 | Convenient syntheses of 3'-amino-2',3'-dideoxynucleosides, their 5'-monophosphates, and 3'-aminoterminal oligodeoxynucleotide primers | The Journal of organic chemistry |
