2-Fluoro-4-biphenylylboronic acid

Name: 2-Fluoro-4-biphenylylboronic acid
Brand: BOC Sciences
Rating: 5 (1 reviews)

Inquiry

Molecular Formula:

C12H10O2BF

Molecular Weight:

216.02

CAS Number:

178305-99-2

Catalog Number:

178305-99-2

Product Information

Molecular Formula:

C12H10O2BF

Molecular Weight:

216.02

Description

2-Fluoro-4-biphenylylboronic acid is a boronic acid derivative commonly used in biomedical research. It is a versatile reagent in Suzuki cross-coupling reactions utilized in the synthesis of several pharmaceutical drugs designed to treat cardiovascular diseases and certain types of cancer.

Synonyms

RARECHEM AH PB 0063; AKOS BRN-0162; 3-FLUOROBIPHENYL; 3-FLUORO-4-PHENYLBENZENEBORONIC ACID; 2-FLUOROBIPHENYL-4-BORONIC ACID; 2-FLUORO[1,1'-BIPHENYL]-4-BORONIC ACID

IUPAC Name

(3-fluoro-4-phenylphenyl)boronic acid

Canonical SMILES

B(C1=CC(=C(C=C1)C2=CC=CC=C2)F)(O)O

InChI

InChI=1S/C12H10BFO2/c14-12-8-10(13(15)16)6-7-11(12)9-4-2-1-3-5-9/h1-8,15-16H

InChI Key

BWYWXDFYJSIUBE-UHFFFAOYSA-N

Boiling Point

377.3°C at 760mmHg

Melting Point

243-248°C

Purity

98%

Density

1.25g/cm3

Computed Properties

Hydrogen Bond Donor Count

Hydrogen Bond Acceptor Count

Rotatable Bond Count

Exact Mass

216.0757879 g/mol

Monoisotopic Mass

216.0757879 g/mol

Topological Polar Surface Area

40.5Å²

Heavy Atom Count

Formal Charge

Complexity

219

Isotope Atom Count

Defined Atom Stereocenter Count

Undefined Atom Stereocenter Count

Defined Bond Stereocenter Count

Undefined Bond Stereocenter Count

Covalently-Bonded Unit Count

Compound Is Canonicalized

Yes

Patents

Publication Number	Title	Priority Date
WO-2020225330-A1	Dhodh inhibitors and their use as antiviral agents	2019-05-07
EP-3965753-A1	Dhodh inhibitors and their use as antiviral agents	2019-05-07
JP-2018170236-A	Nonaqueous electrolyte for batteries and lithium secondary battery	2017-03-30
JP-6884020-B2	Non-aqueous electrolyte for batteries and lithium secondary battery	2017-03-30
JP-2018170487-A	Photoelectric conversion element for image sensor	2016-09-13
JP-6986887-B2	Photoelectric conversion element for image sensor	2016-09-13
JP-2018166200-A	Photoelectric conversion element for image sensor	2016-08-30
JP-6906388-B2	Photoelectric conversion element for image sensor	2016-08-30
CN-108368142-A	The manufacturing method and palladium complex of aromatic compound	2015-12-02
EP-3385270-A1	Method for producing aromatic compound, and palladium complex	2015-12-02