Home
Products
Reagents for Polymerization
Polymerization Catalysts
Cross-Coupling Reaction Catalyst
4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrolo[2,3-b]pyridine

4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrolo[2,3-b]pyridine

Inquiry

Molecular Formula:

C13H17BN2O2

Molecular Weight:

244.10

Product Information

Molecular Formula:

C13H17BN2O2

Molecular Weight:

244.10

Description

4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrolo[2,3-b]pyridine is a potent compound extensively employed in the realm of biomedical research. It manifests a noteworthy propensity as an efficacious anti-cancer entity that selectively perturbs signaling cascades intrinsically linked to cellular proliferation and exquisite growth. Currently, studies have characterized its preclinical efficacy, supporting its use in drug development for a variety of malignancies (including but not limited to breast, lung, and colon tumors).

Synonyms

4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)-1H-PYRROLO[2,3-B]PYRIDINE; 7-Azaindole-4-boronic acid pinacol ester; 1H-Pyrrolo[2,3-b]pyridine, 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; 4-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrolo[2,3-b]pyridine; 1H-Pyrrolo[2,3-B]pyridine-4-boronicacidpinacolester; Z1317588769; 1H-Pyrrolo[2,3-b]pyridine,4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; 4-(4,4,5,5-Tetramethyl-[1,3,2]dioxa borolan-2-yl)-1H-pyrrolo[2,3-b]pyridine; 4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrrolo[2,3-b]pyridine; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrolo[2,3-b]pyridine

IUPAC Name

4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrolo[2,3-b]pyridine

Canonical SMILES

B1(OC(C(O1)(C)C)(C)C)C2=C3C=CNC3=NC=C2

InChI

InChI=1S/C13H17BN2O2/c1-12(2)13(3,4)18-14(17-12)10-6-8-16-11-9(10)5-7-15-11/h5-8H,1-4H3,(H,15,16)

InChI Key

OYFHAWAVFVJOBN-UHFFFAOYSA-N

Flash Point

Not applicable

Safety Information

Hazards

H301

Precautionary Statement

P301 + P310

Computed Properties

Hydrogen Bond Donor Count

Hydrogen Bond Acceptor Count

Rotatable Bond Count

Exact Mass

244.1383080 g/mol

Monoisotopic Mass

244.1383080 g/mol

Topological Polar Surface Area

47.1Å²

Heavy Atom Count

Formal Charge

Complexity

319

Isotope Atom Count

Defined Atom Stereocenter Count

Undefined Atom Stereocenter Count

Defined Bond Stereocenter Count

Undefined Bond Stereocenter Count

Covalently-Bonded Unit Count

Compound Is Canonicalized

Yes

Patents

Publication Number	Title	Priority Date
WO-2021143821-A1	Fused heteroaryl derivative, preparation method therefor, and application thereof in medicine	2020-01-17
CN-113135942-A	Condensed pyrimidine derivative, preparation method and medical application thereof	2020-01-17
CN-113004303-A	Pyrimido-oxazine tricyclic derivative, preparation method and application thereof in medicine	2019-12-18
WO-2021105474-A1	New compounds for treatment of diseases related to dux4 expression	2019-11-29
US-2021107901-A1	Bicyclic amines as cdk2 inhibitors	2019-10-11
WO-2021072232-A1	Bicyclic amines as cdk2 inhibitors	2019-10-11
TW-202128684-A	Bicyclic amines as cdk2 inhibitors	2019-10-11
US-2021078996-A1	Hpk1 antagonists and uses thereof	2019-09-13
US-2021078997-A1	SUBSTITUTED ISOINDOLIN-1-ONES AND 2,3-DIHYDRO-1H-PYRROL[3,4-c]PYRIDIN-1-ONES AS HPK1 ANTAGONISTS	2019-09-13
US-2021078998-A1	SUBSTITUTED ISOINDOLIN-1-ONES AND 2,3-DIHYDRO-1H-PYRROLO[3,4-c]PYRIDIN-1-ONES AS HPK1 ANTAGONISTS	2019-09-13

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass

Concentration

Volume

Molecular Weight *

Calculate

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)