4-Formylphenylboronic acid

Product Information

Molecular Formula
C7H7BO3
Molecular Weight
149.94
Description
4-Formylphenylboronic acid is a versatile compound widely utilized in organic synthesis and molecular chemistry. Known for its ability to form stable covalent bonds with diols, it plays a crucial role in Suzuki-Miyaura cross-coupling reactions, facilitating the formation of carbon-carbon bonds. The compound's unique structural properties make it an essential building block in the creation of complex organic molecules. Its application extends to the development of functional materials and advanced chemical research, showcasing its importance in modern biochemical studies.
Synonyms
Boronic acid, (4-formylphenyl)-; 4-Boronobenzaldehyde; p-formylphenylboronic acid; MFCD00151823; 4-benzaldehyde boronic acid; 4-(Dihydroxyboryl)benzaldehyde; CHEMBL140254
IUPAC Name
(4-formylphenyl)boronic acid
Canonical SMILES
B(C1=CC=C(C=C1)C=O)(O)O
InChI
InChI=1S/C7H7BO3/c9-5-6-1-3-7(4-2-6)8(10)11/h1-5,10-11H
InChI Key
VXWBQOJISHAKKM-UHFFFAOYSA-N
Boiling Point
347.6±44.0 °C (Predicted)
Melting Point
237-242 °C
Flash Point
Not applicable
Purity
95 %
Density
1.240±0.10 g/cm3 (Predicted)
Solubility
Slightly Soluble in Water
Appearance
White to yellowish crystal powder
Storage
2-8 °C
LogP
-0.82110

Safety Information

Hazards
H317
Precautionary Statement
P261, P272, P280, P302+P352, P321, P333+P313, P363, and P501
Signal Word
Warning

Computed Properties

Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
3
Rotatable Bond Count
2
Exact Mass
150.0488242 g/mol
Monoisotopic Mass
150.0488242 g/mol
Topological Polar Surface Area
57.5Ų
Heavy Atom Count
11
Formal Charge
0
Complexity
130
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes

Patents

Publication Number Title Priority Date
CN-114045082-A Composite coating with self-repairing, air-permeable and wear-resistant properties, and preparation method and application thereof 2021-12-14
CN-113896651-A Synthesis method of dominant malachite green hapten and application of hapten 2021-12-06
CN-113896651-B Synthesis method of dominant malachite green hapten and application of hapten 2021-12-06
CN-114133386-A Silver ion complexing agent, preparation method and method for directly converting silver ions in wastewater into antibacterial material 2021-11-30
CN-113896736-A Aryl-substituted spirooxazine photochromic compound and preparation method and application thereof 2021-11-18
CN-114106943-A Multienzyme cleaning agent and processing equipment thereof 2021-11-08
CN-113956274-A Design and synthesis method of fluorescent probe capable of responding to viscosity and peroxynitrite change in epileptic diseases 2021-10-29
CN-113845646-A Dual-functionalized conjugated microporous polymer based on pyrimidine and cyano, and preparation method and application thereof 2021-10-20
CN-113999217-A Novel compound, preparation method and application of novel compound as co-sensitizer 2021-10-19
CN-114181716-A Gas response type Pickering emulsifier, preparation method and application in Suzuki reaction 2021-10-19

Literatures

PMID Publication Date Title Journal
21431183 2011-05-07 Synthesis of tri-substituted biaryl based trianglimines: formation of C3-symmetrical and non-symmetrical regioisomers Organic & biomolecular chemistry
20710065 2010-08-11 Phenylboronic-acid-based carbohydrate binders as antiviral therapeutics: monophenylboronic acids Antiviral chemistry & chemotherapy
20502601 2010-03-11 Efficient and improved synthesis of Telmisartan Beilstein journal of organic chemistry
17537249 2007-05-30 A convenient catalyst system for microwave accelerated cross-coupling of a range of aryl boronic acids with aryl chlorides Beilstein journal of organic chemistry
16848408 2006-07-01 Chitosan-pentaglycine-phenylboronic acid conjugate: a potential colon-specific platform for calcitonin Bioconjugate chemistry
16099661 2005-12-15 Dicationic near-linear biphenyl benzimidazole derivatives as DNA-targeted antiprotozoal agents Bioorganic & medicinal chemistry
12375944 2002-10-18 An exceptional red shift of emission maxima upon fluorine substitution The Journal of organic chemistry
11740104 2001-12-01 Space-group revision for 4-formylphenylboronic acid Acta crystallographica. Section C, Crystal structure communications
The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Related Products

Online Inquiry
  • Verification code
USA
  • International:
  • US & Canada (Toll free):
  • Email:
  • Fax:
UK
Germany
Copyright © 2026 BOC Sciences. All rights reserved.
Top
Inquiry Basket