4-mercaptophenylboronic acid

Product Information

Molecular Formula:
C6H7BO2S
Molecular Weight:
153.99
Description
4-mercaptophenylboronic acid is a biomedical compound used for the treatment of various diseases. It exhibits remarkable potential in targeting cancer cells due to its inhibitory properties on tyrosine kinases. Additionally, it has shown efficacy in the treatment of diabetes by regulating glucose levels. This product plays a crucial role in biomedicine, especially in the development of targeted therapies for cancer and diabetes.
Synonyms
(4-sulfanylphenyl)boronic acid; 4-mercaptophenylboronicacid; Boronic acid, (4-mercaptophenyl)-; (4-mercaptophenyl)boronic acid; 4-mercaptophenyl boronic acid; 4-Mercaptobenzeneboronic Acid; 4-Mercaptophenylboronic acid, 90%; Boronic acid, B-(4-mercaptophenyl)-
IUPAC Name
(4-sulfanylphenyl)boronic acid
Canonical SMILES
B(C1=CC=C(C=C1)S)(O)O
InChI
InChI=1S/C6H7BO2S/c8-7(9)5-1-3-6(10)4-2-5/h1-4,8-10H
InChI Key
AUVSUPMVIZXUOG-UHFFFAOYSA-N
Melting Point
>230 °C (lit.)
Flash Point
Not applicable
Purity
90%
Density
1.27g/cm3

Computed Properties

Hydrogen Bond Donor Count
3
Hydrogen Bond Acceptor Count
3
Rotatable Bond Count
1
Exact Mass
154.0259808 g/mol
Monoisotopic Mass
154.0259808 g/mol
Topological Polar Surface Area
41.5Ų
Heavy Atom Count
10
Formal Charge
0
Complexity
102
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes

Patents

Publication Number Title Priority Date
CN-114057782-A Process method for synthesizing 4-mercapto phenylboronic acid 2021-12-13
CN-114177198-A Nano-gold antibacterial agent and preparation method and application thereof 2021-10-29
CN-113945619-A Preparation method and application of MPBA @ Au-MOF composite material photoelectrochemical sensor 2021-10-18
CN-113925974-A Anticancer compound capable of targeting intestinal tumors and preparation method and application thereof 2021-10-09
CN-113897785-A Preparation method of layer-by-layer self-assembled semiconductor fiber and transistor sensor 2021-09-24
CN-113892946-A Preparation method of sweat sensing bandage based on SERS 2021-09-17
CN-113634240-A Fluorescent magnetic composite nanofiber, and preparation method and application thereof 2021-08-26
CN-113599507-A Preparation method of glucose-triggered active oxygen response injection type composite hydrogel 2021-08-11
CN-113533299-A Microstructure optical fiber sensor 2021-07-14
CN-113563222-A Method for detecting hydrogen peroxide based on surface enhanced Raman scattering of silent zone reporter molecule and application 2021-07-13

Literatures

PMID Publication Date Title Journal
22425223 2012-05-15 Sensitive colorimetric visualization of dihydronicotinamide adenine dinucleotide based on anti-aggregation of gold nanoparticles via boronic acid-diol binding Biosensors & bioelectronics
22302165 2012-04-01 Electrochemically synthesized polymers in molecular imprinting for chemical sensing Analytical and bioanalytical chemistry
21088793 2011-01-14 Synthesis, carbohydrate- and DNA-binding studies of cationic 2,2':6',2''-terpyridineplatinum(II) complexes containing N- and S-donor boronic acid ligands Dalton transactions (Cambridge, England : 2003)
20369262 2010-10-01 Electrochemical recognition for sugars on the chitosan-poly(diallyldimethylammonium chloride)-nano-Prussian blue/nano-Au/4-mercaptophenylboronic acid modified glassy carbon electrode Bioprocess and biosystems engineering
20170134 2010-03-15 Surface plasmon resonance analysis of antibiotics using imprinted boronic acid-functionalized Au nanoparticle composites Analytical chemistry
19834891 2009-11-01 On-plate-selective enrichment of glycopeptides using boronic acid-modified gold nanoparticles for direct MALDI-QIT-TOF MS analysis Proteomics
19844974 2009-11-01 Facile synthesis of 4-mercaptophenylboronic acid functionalized gold nanoparticles for selective enrichment of glycopeptides Rapid communications in mass spectrometry : RCM
20027646 2009-09-01 Piezoresistive cantilever array sensor for consolidated bioprocess monitoring Scanning
19472289 2009-05-01 Synthesis and application of novel phenylboronate affinity materials based on organic polymer particles for selective trapping of glycoproteins Journal of separation science
18522434 2008-07-01 Label-free sugar detection using phenylboronic acid-functionalized piezoresistive microcantilevers Analytical chemistry
The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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