5-Formyl-2-furylboronic acid

Product Information

Molecular Formula:
C5H5BO4
Molecular Weight:
139.90
Description
2-Formylfuran-5-boronic acid is a reagent used in Suzuki cross-couplings with deactivated aryl bromides and activated aryl chlorides.
Synonyms
2-Formyl-5-furanboronic Acid; 5-Formyl-2-furanboronic Acid; 5-Formyl-2-furylboronic Acid; B-(5-Formyl-2-furanyl)boronic Acid; (2-Formylfuran-5-yl)boronic Acid; 2-Formylfuran-5-boronicacid; 5-Formylfuran-2-boronic acid; 5-formylfuran-2-ylboronic acid; 5-Formyl-2-furanboronic Acid; 5-Formyl-2-furanylboronic acid; 5-formylfuran-2-yl-2-boronic acid
IUPAC Name
(5-formylfuran-2-yl)boronic acid
Canonical SMILES
B(C1=CC=C(O1)C=O)(O)O
InChI
InChI=1S/C5H5BO4/c7-3-4-1-2-5(10-4)6(8)9/h1-3,8-9H
InChI Key
JUWYQISLQJRRNT-UHFFFAOYSA-N
Boiling Point
379.3±52.0 °C (Predicted)
Melting Point
136 °C (dec.)
Flash Point
Not applicable
Purity
98% (HPLC)
Density
1.360±0.10 g/cm3 (Predicted)
Solubility
Insoluble in Water
Appearance
Light Grey Powder
Storage
2-8 °C

Safety Information

Hazards
H314
Precautionary Statement
P280 - P305 + P351 + P338 - P310

Computed Properties

Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
4
Rotatable Bond Count
2
Exact Mass
140.0280888 g/mol
Monoisotopic Mass
140.0280888 g/mol
Topological Polar Surface Area
70.7Ų
Heavy Atom Count
10
Formal Charge
0
Complexity
127
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes

Patents

Publication Number Title Priority Date
CN-112687878-A Electrochemical device and electronic device 2020-12-25
WO-2022029795-A1 An environment friendly process for the preparation of Lapatinib Ditosylate of Formula 1(b) 2020-08-04
WO-2021168074-A1 Macrocyclic compounds and uses thereof 2020-02-18
CN-113234065-A Aggregation-induced emission luminophores for photodynamic therapy 2020-01-22
US-2021221799-A1 Aggregation-induced emission luminogens for photodynamic therapy 2020-01-22
WO-2021130638-A1 Diacylglycerol kinase modulating compounds 2019-12-24
KR-20210076876-A Novel indazole derivatives and use thereof 2019-12-16
KR-20210076879-A Novel pyrimidine derivatives and use thereof 2019-12-16
WO-2021125802-A1 Novel indazole derivative, and use thereof 2019-12-16
WO-2021125803-A1 Novel pyrimidin derivative and use thereof 2019-12-16

Literatures

PMID Publication Date Title Journal
12926269 2003-05-07 5-Formyl-2-furylboronic acid as a versatile bifunctional reagent for the synthesis of pi-extended heteroarylfuran systems Organic & biomolecular chemistry
5816 1975-01-01 [Evidence of urinary tubular proteins in inflammatory and toxic kidney damage] Wiener medizinische Wochenschrift. Supplement
The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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