9,9-BIS(3-AMINO-4-HYDROXYPHENYL)FLUORENE

Product Information

Molecular Formula:
C25H20N2O2
Molecular Weight:
380.44
Description
9,9-BIS(3-AMINO-4-HYDROXYPHENYL)FLUORENE is a highly potent compound prevalent in the biomedical realm and exhibits its intrinsic capability to impede the progression of malignant neoplasms. Its distinguished efficacy in combating an array of cancerous ailments, predominantly encompassing breast, lung, and colon cancer, has garnered immense attention. Revolutionary explorations intimate that this chemical entity selectively antagonizes the growth of cancerous cells, thus confining their propagation and instigating cellular demise. Harnessing its potential for the formulation of targeted antineoplastic interventions unveils auspicious avenues for enhancing patient prognoses.
Synonyms
9,9-BIS(3-AMINO-4-HYDROXYPHENYL)FLUORENE; 2,2'-DIAMINO-4,4'-(9-FLUORENYLIDENE)DIPHENOL; 2,2'-DIHYDROXY-5,5'-(9-FLUORENYLIDENE)DIANILINE; 9,9-BIS(3-AMINO-4-HYDROXYPHENYL)FLUORENE 98+% T
IUPAC Name
2-amino-4-[9-(3-amino-4-hydroxyphenyl)fluoren-9-yl]phenol
Canonical SMILES
C1=CC=C2C(=C1)C3=CC=CC=C3C2(C4=CC(=C(C=C4)O)N)C5=CC(=C(C=C5)O)N
InChI
InChI=1S/C25H20N2O2/c26-21-13-15(9-11-23(21)28)25(16-10-12-24(29)22(27)14-16)19-7-3-1-5-17(19)18-6-2-4-8-20(18)25/h1-14,28-29H,26-27H2
InChI Key
NLGOBIIKXFNGQR-UHFFFAOYSA-N
Purity
>98.0%(LC)
Appearance
White to Green to Brown powder to crystal

Safety Information

Hazards
H315:
Causes skin irritation.
H319:
Causes serious eye irritation.
Precautionary Statement
P264:
Wash thoroughly after handling.
P280:
Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352:
IF ON SKIN:
Wash with plenty of soap and water.
P332+P313:
If skin irritation occurs:
Get medical advice/attention.
P337+P313:
If eye irritation persists:
Get medical advice/attention.
P362+P364:
Take off contaminated clothing. [As modified by IV ATP].
And wash it before reuse. [Added by IV ATP].

Computed Properties

XLogP3
4.6
Hydrogen Bond Donor Count
4
Hydrogen Bond Acceptor Count
4
Rotatable Bond Count
2
Exact Mass
380.152477885 g/mol
Monoisotopic Mass
380.152477885 g/mol
Topological Polar Surface Area
92.5Ų
Heavy Atom Count
29
Formal Charge
0
Complexity
533
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes

Patents

Publication Number Title Priority Date
CN-113527731-A Preparation method of transparent polyimide film 2021-06-29
JP-6950844-B1 Curable composition, cured product and method for producing the same 2020-09-25
JP-2020152922-A Fine particle-containing composition 2020-06-24
JP-6861313-B2 Fine particle-containing composition 2020-06-24
WO-2021220919-A1 Method for producing surface-modified metal oxide microparticles, method for producing surface-modified metal oxide microparticle dispersion, and method for producing solid product 2020-05-01
WO-2021220920-A1 Method for producing surface-modified metal oxide microparticles, surface-modified metal oxide microparticles, surface-modified metal oxide microparticle dispersion, solid product, method for producing surface-modified metal oxide microparticle dispersion, and method for producing solid product 2020-05-01
JP-2021172734-A Polyimide precursor, polyimide resin composition, polyimide resin film and method for producing the same. 2020-04-24
JP-2021175790-A Polyimide precursor and resin composition containing it, polyimide resin film, resin film and method for producing the same. 2020-04-24
KR-20210131899-A Polyimide precursor and resin composition containing same, polyimide resin film, resin film and method of producing same 2020-04-24
JP-2021166984-A Gas storage and release compounds 2020-04-13

Literatures

PMID Publication Date Title Journal
17487306 2007-05-01 Comparative study of the bimolecular electron transfer of fullerenes (C60/C70) and 9,9-disubstituted fluorenes by laser flash photolysis Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology
The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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