Benzyl glycidyl ether
Product Information
Molecular Formula
C10H12O2
Molecular Weight
164.20
Description
Benzyl glycidyl ether is a remarkable biomedical compound harnessed in the advancement of pharmaceutical drugs and assumes paramount significance. Its extraordinary attributes render it an invaluable constituent in the synthesis of antitumor agents and cardiovascular medication, revolutionizing the treatment landscape for numerous ailments spanning cancer and heart-related conditions. The intricate modus operandi of this compound unequivocally showcases its potential as an efficacious therapeutic entity within the biomedical realm.
Synonyms
Oxirane, 2-[(phenylmethoxy)methyl]-; 2-[(Phenylmethoxy)methyl]oxirane; Oxirane, [(phenylmethoxy)methyl]-; Propane, 1-(benzyloxy)-2,3-epoxy-; (Benzyloxymethyl)oxirane; (±)-O-Benzylglycidol; 1-(Benzyloxy)-2,3-epoxypropane; 2-(Benzyloxymethyl)oxirane; 2-[[(Benzyloxy)methyl]oxy]oxirane; 3-(Benzyloxy)-1,2-epoxypropane; [(Phenylmethoxy)methyl]oxirane; Diluent 692; Glycidol benzyl ether; Glycidyl benzyl ether; JX 011; LS 692; NXA 692; Xinyuan 692; XY 692; YS 692
IUPAC Name
2-(phenylmethoxymethyl)oxirane
SMILES
C1C(O1)COCC2=CC=CC=C2
InChI
InChI=1S/C10H12O2/c1-2-4-9(5-3-1)6-11-7-10-8-12-10/h1-5,10H,6-8H2
InChI Key
QNYBOILAKBSWFG-UHFFFAOYSA-N
Boiling Point
78-80°C
Purity
≥95%
Density
1.0960 g/cm³
Appearance
Colorless to Light Yellow Clear Liquid
Storage
Store at 2-8°C
Refractive Index
1.52
LogP
1.60200
Related CAS
89616-40-0 (Deleted CAS) 2110438-10-1 (Deleted CAS)
Safety Information
Hazards
H315:
Causes skin irritation.
H319:
Causes serious eye irritation.
H341:
Suspected of causing genetic defects.
Causes skin irritation.
H319:
Causes serious eye irritation.
H341:
Suspected of causing genetic defects.
Precautionary Statement
P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501
Signal Word
Warning
Computed Properties
XLogP3
1.3
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
2
Rotatable Bond Count
4
Exact Mass
164.083729621 g/mol
Monoisotopic Mass
164.083729621 g/mol
Topological Polar Surface Area
21.8Ų
Heavy Atom Count
12
Formal Charge
0
Complexity
130
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
1
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| CN-114163934-A | Method for improving binding force between steel plate and mortar | 2021-12-23 |
| CN-114181651-A | Elastic easily-detachable epoxy floor glue and preparation method thereof | 2021-12-20 |
| CN-113980425-A | Foam filler and preparation method thereof | 2021-11-30 |
| CN-114133841-A | Super-black coating, LED display screen and preparation method of LED display screen | 2021-11-30 |
| CN-114133825-A | Solvent-free epoxy resin coating and preparation method and application thereof | 2021-11-25 |
| CN-114163614-A | Epoxy curing agent and preparation method and application thereof | 2021-11-22 |
| CN-114031896-A | Epoxy resin composition for carbon fiber winding and preparation method thereof | 2021-11-20 |
| CN-113860797-A | High-strength lightweight aggregate for concrete and preparation method thereof | 2021-11-19 |
| CN-113930052-A | Pultrusion method of high-viscosity epoxy resin composition for carbon fiber | 2021-11-18 |
| CN-113980623-A | Bio-based high-strength joint filling repair heat insulation material and preparation method thereof | 2021-11-18 |
Literatures
| PMID | Publication Date | Title | Journal |
|---|---|---|---|
| 22052437 | 2012-08-01 | Bioresolution of benzyl glycidyl ether using whole cells of Bacillus alcalophilus | Journal of basic microbiology |
| 22526421 | 2012-08-01 | Biocatalytic resolution of benzyl glycidyl ether and its derivates by Talaromyces flavus: effect of phenyl ring substituents on enantioselectivity | Biotechnology letters |
| 20549284 | 2011-04-01 | Marine fungi Aspergillus sydowii and Trichoderma sp. catalyze the hydrolysis of benzyl glycidyl ether | Marine biotechnology (New York, N.Y.) |
| 17875334 | 2007-10-15 | Cloning of an epoxide hydrolase-encoding gene from Aspergillus niger M200, overexpression in E. coli, and modification of activity and enantioselectivity of the enzyme by protein engineering | Journal of biotechnology |
| 16343776 | 2006-02-01 | Purification and characterisation of a novel enantioselective epoxide hydrolase from Aspergillus niger M200 | Biochimica et biophysica acta |
| 16061300 | 2005-12-06 | Novel microbial epoxide hydrolases for biohydrolysis of glycidyl derivatives | Journal of biotechnology |
| 15471449 | 2004-10-15 | Synthesis of 4-deoxy-L-(and D-)hexoses from chiral noncarbohydrate building blocks | The Journal of organic chemistry |
| 14552765 | 2003-11-03 | Practical, asymmetric synthesis of 16-hydroxyeicosa-5(Z),8(Z), 11(Z),14(Z)-tetraenoic acid (16-HETE), an endogenous inhibitor of neutrophil activity | Bioorganic & medicinal chemistry letters |
| 11412980 | 2001-06-18 | Discovery and characterization of the potent, selective and orally bioavailable MMP inhibitor ABT-770 | Bioorganic & medicinal chemistry letters |
