1,2-Bis(2,3-epoxypropoxy)ethane
Product Information
Molecular Formula
C8H14O4
Molecular Weight
174.19436
Description
1,2-Bis(2,3-epoxypropoxy)ethane is a versatile synthetic reagent widely used in biomedical research. Its specific epoxy groups enable cross-linking in polymers, useful for drug delivery systems. This compound also possesses cytotoxicity, advancing cancer therapeutic research.
Synonyms
Ethyleneglycoldiglycidylether; 1,2-Bis(2,3-epoxypropoxy)ethane; 2224-15-9; Glycoldiglycidylether; 1,2-Diglycidyloxyethane; Diglycidylethyleneglycol
IUPAC Name
2-[2-(oxiran-2-ylmethoxy)ethoxymethyl]oxirane
SMILES
C1C(O1)COCCOCC2CO2
InChI
InChI=1S/C8H14O4/c1(9-3-7-5-11-7)2-10-4-8-6-12-8/h7-8H,1-6H2
InChI Key
AOBIOSPNXBMOAT-UHFFFAOYSA-N
Boiling Point
112°C (4.5 mmHg)
Flash Point
>230 °CF
Purity
98%
Density
1.118
Appearance
Clear yellow liquid
Storage
2-8°C
Refractive Index
n20/D 1.463(lit.)
LogP
-0.18280
Vapor Pressure
0.172mmHg at 25°C
Safety Information
Hazards
H315:
Causes skin irritation.
H319:
Causes serious eye irritation.
H341:
Suspected of causing genetic defects.
Causes skin irritation.
H319:
Causes serious eye irritation.
H341:
Suspected of causing genetic defects.
Precautionary Statement
P201:
Obtain special instructions before use.
P264:
Wash thoroughly after handling.
P280:
Wear protective gloves/protective clothing/eye protection/face protection.
P308+P313:
If exposed or concerned:
Get medical advice/attention.
P337+P313:
If eye irritation persists:
Get medical advice/attention.
P501:
Dispose of contents/container in accordance with local/regional/national/international regulations.
Obtain special instructions before use.
P264:
Wash thoroughly after handling.
P280:
Wear protective gloves/protective clothing/eye protection/face protection.
P308+P313:
If exposed or concerned:
Get medical advice/attention.
P337+P313:
If eye irritation persists:
Get medical advice/attention.
P501:
Dispose of contents/container in accordance with local/regional/national/international regulations.
Computed Properties
XLogP3
-0.7
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
4
Rotatable Bond Count
7
Exact Mass
174.08920892 g/mol
Monoisotopic Mass
174.08920892 g/mol
Topological Polar Surface Area
43.5Ų
Heavy Atom Count
12
Formal Charge
0
Complexity
123
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
2
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| EP-3677244-A2 | Compositions comprising multilamellar vesicles | 2020-02-04 |
| EP-3842469-A1 | Material for forming organic film, method for forming organic film, patterning process, and compound | 2019-12-26 |
| US-2021190718-A1 | Analyte Sensors and Sensing Methods Featuring Low-Potential Detection | 2019-12-23 |
| US-2021190719-A1 | Analyte sensors and sensing methods featuring low-potential detection | 2019-12-23 |
| WO-2021124125-A1 | Process for the preparation of a bonding resin | 2019-12-20 |
| WO-2021124129-A1 | Process for preparing a bonding resin | 2019-12-20 |
| WO-2021124668-A1 | Adhesive composition | 2019-12-20 |
| WO-2021124726-A1 | Fiber-reinforced resin molding material, fiber-reinforced resin molded article, and method for manufacturing fiber-reinforced resin molded article | 2019-12-20 |
| WO-2021124854-A1 | Adhesive sheet | 2019-12-20 |
| WO-2021124855-A1 | Adhesive sheet | 2019-12-20 |
Literatures
| PMID | Publication Date | Title | Journal |
|---|---|---|---|
| 21556975 | 2011-06-01 | Extruded collagen fibres for tissue engineering applications: effect of crosslinking method on mechanical and biological properties | Journal of materials science. Materials in medicine |
