3-glycidoxypropyltrimethoxysilane
Product Information
Molecular Formula
C9H20O5Si
Molecular Weight
236.34
Description
3-Glycidoxypropyltrimethoxysilane assumes the role of an eminent coupling agent and surface modifier. Its multifaceted application realm stretches from biomaterial synthesis to drug delivery systems. The exceptional chemical attributes it possesses facilitate boosted adhesion and compatibility, rendering it ideal for amalgamating diverse entities, encompassing metals, plastics, and biological matrices.
Synonyms
(3-Glycidoxypropyl)trimethoxysilane; Silicone KBM 403; Silane A 187; trimethoxy-[3-(oxiran-2-ylmethoxy)propyl]silane; Silane coupler KH-560
IUPAC Name
trimethoxy-[3-(oxiran-2-ylmethoxy)propyl]silane
SMILES
CO[Si](CCCOCC1CO1)(OC)OC
InChI
InChI=1S/C9H20O5Si/c1-10-15(11-2,12-3)6-4-5-13-7-9-8-14-9/h9H,4-8H2,1-3H3
InChI Key
BPSIOYPQMFLKFR-UHFFFAOYSA-N
Flash Point
122 °C(251.6 °F)
Purity
>95.0%(GC)
Density
1.070 g/mL at 20 °C
Solubility
Soluble in Acetonitrile (Slightly), Chloroform
Appearance
Colorless transparent liquid
Application
GPTMS is widely used as a silica precursor.
Refractive Index
1.429 (lit.)
Vapor Pressure
0.002 [mmHg]
Safety Information
Hazards
H315:
Causes skin irritation.
H319:
Causes serious eye irritation.
Causes skin irritation.
H319:
Causes serious eye irritation.
Precautionary Statement
P264:
Wash thoroughly after handling.
P280:
Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352:
IF ON SKIN:
Wash with plenty of soap and water.
P332+P313:
If skin irritation occurs:
Get medical advice/attention.
P337+P313:
If eye irritation persists:
Get medical advice/attention.
P362+P364:
Take off contaminated clothing. [As modified by IV ATP].
And wash it before reuse. [Added by IV ATP].
Wash thoroughly after handling.
P280:
Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352:
IF ON SKIN:
Wash with plenty of soap and water.
P332+P313:
If skin irritation occurs:
Get medical advice/attention.
P337+P313:
If eye irritation persists:
Get medical advice/attention.
P362+P364:
Take off contaminated clothing. [As modified by IV ATP].
And wash it before reuse. [Added by IV ATP].
Signal Word
Danger
Computed Properties
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
5
Rotatable Bond Count
9
Exact Mass
236.10800027 g/mol
Monoisotopic Mass
236.10800027 g/mol
Topological Polar Surface Area
49.4Ų
Heavy Atom Count
15
Formal Charge
0
Complexity
166
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
1
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| US-9214440-B1 | Method for preventing die pad delamination | 2014-12-17 |
| US-2015377608-A1 | Method for determining the weight and thickness of a passivation ornconversion coating on a substrate | 2014-06-30 |
| US-2015378489-A1 | Transparent conductive layer, method for manufacturing the same and display device including the same | 2014-06-30 |
| US-2015376350-A1 | Low-density molding compound containing surface derivatized microspheres | 2014-06-27 |
| US-2015376355-A1 | Photosensitive resin composition, protective film and element having the same | 2014-06-27 |
| US-2015378256-A1 | Photosensitive resin composition, protective film and element having the same | 2014-06-27 |
| WO-2015200421-A1 | Uv-curable coating compositions for glass based on epoxy/oxetane compounds, epoxy functionalized silsesquioxane and epoxy functionalized nanoparticles. | 2014-06-27 |
| WO-2015200811-A1 | Low-density molding compound containing surface derivatized microspheres | 2014-06-27 |
| EP-2960298-A1 | Actinic radiation and moisture dual curable composition | 2014-06-26 |
| US-2015376476-A1 | Actinic radiation and moisture dual curable composition | 2014-06-26 |
Literatures
| PMID | Publication Date | Title | Journal |
|---|---|---|---|
| 22884206 | 2012-09-12 | Role of precursors and coating polymers in sol-gel chemistry toward enhanced selectivity and efficiency in solid phase microextraction | Analytica chimica acta |
| 22806722 | 2012-09-01 | Green coconut fiber: a novel carrier for the immobilization of commercial laccase by covalent attachment for textile dyes decolourization | World journal of microbiology & biotechnology |
| 22758781 | 2012-08-01 | Release of ceria nanoparticles grafted on hybrid organic-inorganic films for biomedical application | ACS applied materials & interfaces |
| 22649791 | 2012-07-21 | Size-dependence enhancement in electrocatalytic activity of NiHCF-gold nanocomposite: potential application in electrochemical sensing | The Analyst |
| 22410151 | 2012-07-13 | Hydrophilic modification of silica-titania mesoporous materials as restricted-access matrix adsorbents for enrichment of phosphopeptides | Journal of chromatography. A |
| 22672980 | 2012-07-01 | Photodynamic inactivation of Candida albicans using bridged polysilsesquioxane films doped with porphyrin | Bioorganic & medicinal chemistry |
| 22537474 | 2012-06-01 | Immobilization and characterization of hemoglobin on modified sporopollenin surfaces | International journal of biological macromolecules |
| 22852374 | 2012-05-01 | Transparent nanocomposites of high refractive index based on epoxy resin and TiO2 nanoparticle | Journal of nanoscience and nanotechnology |
| 22305908 | 2012-03-09 | Immobilization of chitosan in sol-gel phases for chiral open-tubular capillary electrochromatography | Analytica chimica acta |
| 22081133 | 2012-01-21 | 3-Glycidoxypropyltrimethoxysilane mediated in situ synthesis of noble metal nanoparticles: application to hydrogen peroxide sensing | The Analyst |
