Boc-5-aminovaleric acid
Product Information
Molecular Formula
C10H19NO4
Molecular Weight
217.26
Description
Boc-5-aminovaleric acid is a modified amino acid featuring a tert-butoxycarbonyl (Boc) protective group. This chemical moiety stabilizes the molecule during peptide synthesis, ensuring selective reactions at targeted sites without unwanted side reactions. Its crystalline form guarantees consistency in experimental conditions, while its solubility in organic solvents facilitates diverse synthetic applications. Researchers utilize Boc-5-aminovaleric acid in the design of novel drugs and peptides, contributing to advancements in therapeutic development and protein engineering.
Synonyms
Boc-5-Ava-OH; Boc-5-aminopentanoic acid; Boc 5 Ava OH
IUPAC Name
5-[(2-methylpropan-2-yl)oxycarbonylamino]pentanoic acid
SMILES
CC(C)(C)OC(=O)NCCCCC(=O)O
InChI
InChI=1S/C10H19NO4/c1-10(2,3)15-9(14)11-7-5-4-6-8(12)13/h4-7H2,1-3H3,(H,11,14)(H,12,13)
InChI Key
GFMRZAMDGJIWRB-UHFFFAOYSA-N
Boiling Point
160-168 °C at 0.8 mmHg
Melting Point
48-52°C
Flash Point
>230 °F
Purity
≥ 97% (HPLC)
Density
1.083 g/cm3
Appearance
White to off-white powder
Storage
Store at 2-8 °C
Refractive Index
1.4500 (estimate)
Safety Information
Hazards
H315 - H319 - H335
Precautionary Statement
P302 + P352 - P305 + P351 + P338
Computed Properties
XLogP3
1.1
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
4
Rotatable Bond Count
7
Exact Mass
217.13140809 g/mol
Monoisotopic Mass
217.13140809 g/mol
Topological Polar Surface Area
75.6Ų
Heavy Atom Count
15
Formal Charge
0
Complexity
220
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| AU-2021103482-A4 | Amino acids and peptide conjugates of dopamine | 2021-06-19 |
| CN-113292616-A | Monosaccharide ligand functionalized cationic lipid compound and preparation method and application thereof | 2021-05-20 |
| CN-112390782-A | Compound for specifically enhancing spatial coupling degree of TRPV4-KCa2.3 complex and application thereof | 2020-11-09 |
| CN-112390782-B | Compound for specifically enhancing spatial coupling degree of TRPV4-KCa2.3 complex and application thereof | 2020-11-09 |
| KR-102320536-B1 | Composition for detecting or measuring analytes | 2020-09-04 |
| WO-2022050529-A1 | Composition for detecting or measuring analyte | 2020-09-04 |
| WO-2022042707-A1 | Cyclic-amp response element binding protein (cbp) and/or adenoviral e1a binding protein of 300 kda (p300) degradation compounds and methods of use | 2020-08-27 |
| WO-2022047008-A1 | Hsp90-binding conjugates and formulations thereof | 2020-08-26 |
| WO-2021222114-A1 | Bcl-2 protein inhibitors | 2020-04-28 |
| WO-2021221760-A2 | Expanding the chemical substrates for genetic code reprogramming to include long chain carbon and cyclic amino acids | 2020-02-14 |
