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Boc-5-aminovaleric acid

Product Information

Molecular Formula:
C10H19NO4
Molecular Weight:
217.26
Description
Boc-5-aminovaleric acid is a protected derivative of 5-aminovaleric acid, frequently utilized in peptide synthesis and medicinal chemistry. The Boc (tert-butoxycarbonyl) group effectively safeguards the amino functionality, allowing selective deprotection and downstream modifications in multi-step synthesis workflows. Exhibiting good solubility in organic solvents, this compound facilitates the assembly of peptide chains and the design of bioactive molecules. Its structural attributes make it advantageous for probing enzyme specificity and engineering novel biomolecules in research settings.
Synonyms
Boc-5-Ava-OH; Boc-5-aminopentanoic acid; Boc 5 Ava OH
IUPAC Name
5-[(2-methylpropan-2-yl)oxycarbonylamino]pentanoic acid
Canonical SMILES
CC(C)(C)OC(=O)NCCCCC(=O)O
InChI
InChI=1S/C10H19NO4/c1-10(2,3)15-9(14)11-7-5-4-6-8(12)13/h4-7H2,1-3H3,(H,11,14)(H,12,13)
InChI Key
GFMRZAMDGJIWRB-UHFFFAOYSA-N
Boiling Point
160-168 °C at 0.8 mmHg
Melting Point
48-52°C
Flash Point
>230 °F
Purity
≥ 97% (HPLC)
Density
1.083 g/cm3
Appearance
White to off-white powder
Storage
Store at 2-8 °C
Refractive Index
1.4500 (estimate)

Safety Information

Hazards
H315 - H319 - H335
Precautionary Statement
P302 + P352 - P305 + P351 + P338

Computed Properties

XLogP3
1.1
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
4
Rotatable Bond Count
7
Exact Mass
217.13140809 g/mol
Monoisotopic Mass
217.13140809 g/mol
Topological Polar Surface Area
75.6Ų
Heavy Atom Count
15
Formal Charge
0
Complexity
220
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes

Patents

Publication Number Title Priority Date
AU-2021103482-A4 Amino acids and peptide conjugates of dopamine 2021-06-19
CN-113292616-A Monosaccharide ligand functionalized cationic lipid compound and preparation method and application thereof 2021-05-20
CN-112390782-A Compound for specifically enhancing spatial coupling degree of TRPV4-KCa2.3 complex and application thereof 2020-11-09
CN-112390782-B Compound for specifically enhancing spatial coupling degree of TRPV4-KCa2.3 complex and application thereof 2020-11-09
KR-102320536-B1 Composition for detecting or measuring analytes 2020-09-04
WO-2022050529-A1 Composition for detecting or measuring analyte 2020-09-04
WO-2022042707-A1 Cyclic-amp response element binding protein (cbp) and/or adenoviral e1a binding protein of 300 kda (p300) degradation compounds and methods of use 2020-08-27
WO-2022047008-A1 Hsp90-binding conjugates and formulations thereof 2020-08-26
WO-2021222114-A1 Bcl-2 protein inhibitors 2020-04-28
WO-2021221760-A2 Expanding the chemical substrates for genetic code reprogramming to include long chain carbon and cyclic amino acids 2020-02-14
The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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