Carboxymethyl cellulose sodium

Product Information

Molecular Formula:
[C6H7O2(OH)x(C2H2O3Na)y]n
Description
Carboxymethyl cellulose sodium is widely used in oral and topical pharmaceutical formulations, mainly because of its viscosity-increasing properties. Carboxymethyl cellulose sodium can also be used as a tablet binder, disintegrant and stabilizing emulsion.
Synonyms
Carmellose Sodium; Cellulose, carboxymethyl ether, sodium salt; Akucell; Aqualon CMC; Aquasorb; Blanose; Carbose D; Cel-O-Brandt; Cellulose gum; Cethylose; CMC sodium; E466; Finnfix; Glykocellan; Nymcel ZSB; SCMC; sodium carboxymethylcellulose; sodium cellulose glycolate; Sunrose; Tylose CB; Tylose MGA; Walocel C; Xylo-Mucine
IUPAC Name
sodium2,3,4,5,6-pentahydroxyhexanalacetate
Canonical SMILES
CC(=O)[O-].C(C(C(C(C(C=O)O)O)O)O)O.[Na+]
InChI
InChI=1S/C6H12O6.C2H4O2.Na/c7-1-3(9)5(11)6(12)4(10)2-81-2(3)4/h1,3-6,8-12H,2H21H3,(H,3,4)/q+1/p-1
InChI Key
QMGYPNKICQJHLN-UHFFFAOYSA-M
Melting Point
>228°C (dec.)
Flash Point
Not applicable
Purity
98%
Density
0.52 g/cm3
Solubility
Soluble in Aqueous Acid (Heated, Sonicated, Sparingly), Water (Heated, Sonicated, Sparingly)
Appearance
Off-white to Pale Beige Solid
Application
Used in drilling muds, detergents, resin emulsion paints, adhesives, printing inks, and textile sizes; Also used as a protective colloid, a stabilizer for foods, and a pharmaceutical additive; Used as a bulk laxative, emulsifier and thickener in cosmetics and pharmaceuticals, and stabilizer for reagents; Formerly registered in the US for use as an insecticide for ornamentals and flowering plants; [NPIRS] Permitted for use as an inert ingredient in non-food pesticide products; Used as an anticaking agent, drying agent, emulsifier, formulation aid, humectant, stabilizer or thickener, and texturizer in foods.
Storage
Store at RT
LogP
-4.62260

Computed Properties

Hydrogen Bond Donor Count
5
Hydrogen Bond Acceptor Count
8
Rotatable Bond Count
5
Exact Mass
262.06646171 g/mol
Monoisotopic Mass
262.06646171 g/mol
Topological Polar Surface Area
158Ų
Heavy Atom Count
17
Formal Charge
0
Complexity
173
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
4
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
3
Compound Is Canonicalized
Yes

Patents

Publication Number Title Priority Date
WO-2022034889-A1 Polysaccharide derivative, polysaccharide derivative-drug conjugate, and method for producing same 2020-08-14
CN-111676698-B Modified carbon fiber with composite mechanical interlocking structure interface and composite material thereof 2020-07-27
WO-2022020761-A1 Covering assembly with coagulant compartment and uses thereof in a blood monitoring/management system 2020-07-23
DE-102020209041-A1 "Means for the treatment of keratin fibers with complexing agent and amino acid and/or protein hydrolyzate" 2020-07-20
DE-102020207461-A1 Thickened alkalizing component for oxidative hair lightening agent 2020-06-17
DE-102020207463-A1 Thickened alkalizing component for oxidative hair dye 2020-06-17
WO-2021252761-A2 Monomeric and oligomeric compound embodiments as contraceptives and therapies and methods of making and using the same 2020-06-11
WO-2021233242-A1 Sweetener and flavor compositions containing terpene glycosides 2020-05-19
WO-2021058074-A1 Positive particle electrode for a secondary battery and method for producing same from a nanofibre membrane structure 2019-09-26
WO-2020252522-A1 Antibacterial dosage regime using cannabinoids 2019-06-18

Literatures

PMID Publication Date Title Journal
17629262 2007-08-09 4-amino-5-substituted-3(2H)-pyridazinones as orally active antinociceptive agents: synthesis and studies on the mechanism of action Journal of medicinal chemistry
1175 1975-12-01 The effect of splenectomy on the hematology and on the activity of delta-aminolevulinic acid dehydratase (ALA-D) in hemopoietic tissues of the dogfish, Scyliorhinus canicula (Elasmobranchii) Comparative biochemistry and physiology. A, Comparative physiology
5816 1975-01-01 [Evidence of urinary tubular proteins in inflammatory and toxic kidney damage] Wiener medizinische Wochenschrift. Supplement
The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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