Cphos

Product Information

Molecular Formula:
C28H41N2P
Molecular Weight:
436.61
Description
CPhos can be used:• As a ligand in the Pd-catalyzed synthesis of 3-cyclopentylindole derivatives, dihydrobenzofurans and trans-bicyclic sulfamides.• To synthesize palladacycle precatalysts for Negishi coupling of secondary alkylzinc.
Synonyms
2-Dicyclohexylphosphino-2',6'-bis(N,N-dimethylamino)biphenyl
IUPAC Name
2-(2-dicyclohexylphosphanylphenyl)-1-N,1-N,3-N,3-N-tetramethylbenzene-1,3-diamine
Canonical SMILES
CN(C)C1=C(C(=CC=C1)N(C)C)C2=CC=CC=C2P(C3CCCCC3)C4CCCCC4
InChI
InChI=1S/C28H41N2P/c1-29(2)25-19-13-20-26(30(3)4)28(25)24-18-11-12-21-27(24)31(22-14-7-5-8-15-22)23-16-9-6-10-17-23/h11-13,18-23H,5-10,14-17H2,1-4H3
InChI Key
DRNAQRXLOSUHBQ-UHFFFAOYSA-N
Melting Point
108-113 °C
Flash Point
Not applicable
Purity
98%

Safety Information

Hazards
H315 - H319 - H335
Precautionary Statement
P302 + P352 - P305 + P351 + P338
Signal Word
Warning

Computed Properties

XLogP3
7
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
2
Rotatable Bond Count
6
Exact Mass
436.30073631 g/mol
Monoisotopic Mass
436.30073631 g/mol
Topological Polar Surface Area
6.5Ų
Heavy Atom Count
31
Formal Charge
0
Complexity
489
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes

Patents

Publication Number Title Priority Date
JP-2021075535-A Chemical methods for preparing pyrimidine derivatives and their intermediates 2021-01-14
CN-112778267-A Thiophene-3 (2H) -ketone compound and synthetic method thereof 2020-12-31
CN-112457267-A Preparation method of isoxazoline insecticide 2020-11-27
WO-2022051567-A1 Substituted pyrido[2,3-b]pyrazinones and reuated compounds and their use in treating medicau conditions 2020-09-04
US-2022064375-A1 Polyesters and Polyketoesters from Carbonylative Terpolymerization of enols, Methods to Produce, Blends, and Articles Therefrom 2020-09-01
WO-2022028586-A1 Compounds as c5ar inhibitors 2020-08-07
WO-2022006543-A1 5-[5-(piperidin-4-yl)thieno[3,2-c]pyrazol-2-yl]indazole derivatives and related compounds as modulators for splicing nucleic acids and for the treatment of proliferative diseases 2020-07-02
WO-2021255698-A1 Heterocyclic compound and an organic electroluminescence device comprising the heterocyclic compound 2020-06-19
JP-2021195367-A Cyclopropyldihydroquinoline sulfonamide compound 2020-06-10
JP-2021195368-A Cyclobutyldihydroquinoline sulfonamide compound 2020-06-10
The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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