Ethyl cellulose

Product Information

Molecular Formula:
C19H36O11
Molecular Weight:
440.5
Description
Film-former in coatings, hot-melt adhesives and transfer inks and as a plastic coating for a variety of substrates.
Synonyms
Cellulose ethyl ether; Ethylcellulose; Aquacoat ECD; Aqualon; Ashacel; E462; Ethocel; ethylcellulosum; Surelease
IUPAC Name
2-[4,5-diethoxy-2-(ethoxymethyl)-6-methoxyoxan-3-yl]oxy-6-(hydroxymethyl)-5-methoxyoxane-3,4-diol
Canonical SMILES
CCOCC1C(C(C(C(O1)OC)OCC)OCC)OC2C(C(C(C(O2)CO)OC)O)O
InChI
InChI=1S/C20H38O11/c1-6-26-10-12-16(17(27-7-2)18(28-8-3)20(25-5)30-12)31-19-14(23)13(22)15(24-4)11(9-21)29-19/h11-23H,6-10H2,1-5H3
InChI Key
ZZSNKZQZMQGXPY-UHFFFAOYSA-N
Boiling Point
654.2±55.0 °C at 760 mmHg
Melting Point
240-255ºC
Flash Point
Not applicable
Purity
48.0-49.5%
Density
1.14 g/mL at 25°C
Solubility
Soluble in Chloroform, Ethanol (95%), Ethyl Acetate, Methanol, Toluene; Practically insoluble in Glycerin, Propylene Glycol, Water
Appearance
White to Light Tan-Colored Powder
Application
Used to make plastics, lacquers, adhesives, and wire insulation; Also used in pharmaceuticals (tablet binder), food packaging (coatings, inks, and sealing gaskets), hot-melt adhesives (cables, paper, and textiles), casings for rocket propellants, feed additive, thermoplastic molding powders and sheeting, and textile printing inks.
Storage
Store at RT
Refractive Index
n20/D 1.47 (lit.)
Stability
Stable under normal temperatures and pressures.
LogP
5.5 (LogP)

Computed Properties

XLogP3
-1.5
Hydrogen Bond Donor Count
3
Hydrogen Bond Acceptor Count
11
Rotatable Bond Count
12
Exact Mass
454.24141202 g/mol
Monoisotopic Mass
454.24141202 g/mol
Topological Polar Surface Area
135Ų
Heavy Atom Count
31
Formal Charge
0
Complexity
496
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
10
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes

Literatures

PMID Publication Date Title Journal
22964399 2012-11-15 Polymer coating of carrier excipients modify aerosol performance of adhered drugs used in dry powder inhalation therapy International journal of pharmaceutics
22200122 2012-10-01 Preparation and in vivo evaluation of spray dried matrix type controlled-release microparticles of tamsulosin hydrochloride for orally disintegrating tablet Drug development and industrial pharmacy
23009990 2012-10-01 Formulation development and investigation of ibuprofen controlled release tablets with hydrophilic polymers and the effect of co-excipients on drug release patterns Pakistan journal of pharmaceutical sciences
22698863 2012-09-15 Thymol nanospheres as an effective anti-bacterial agent International journal of pharmaceutics
22528979 2012-08-01 The development of thermal nanoprobe methods as a means of characterizing and mapping plasticizer incorporation into ethylcellulose films Pharmaceutical research
22561957 2012-08-01 Comprehensive study of dynamic curing effect on tablet coating structure European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V
22957434 2012-08-01 In vitro and in vivo evaluation of novel osmotic pump tablets of isosorbide-5-mononitrate containing polyvinyl pyrrolidone (PVP) for controlled release Die Pharmazie
21222508 2012-07-01 Optimization and prediction of drug release from matrix tablets using response surface methodology and near infrared chemical imaging Pharmaceutical development and technology
22525085 2012-07-01 A floating multiparticulate system for ofloxacin based on a multilayer structure: In vitro and in vivo evaluation International journal of pharmaceutics
22539197 2012-07-01 Study of pharmaceutical coatings by means of NMR cryoporometry and SEM image analysis Journal of pharmaceutical sciences
The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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