Guaiacol glycidyl ether

Product Information

Molecular Formula:
C10H12O3
Molecular Weight:
180.20
Description
1-(2,3-Epoxypropoxy)-2-methoxybenzene is one of Ranolazine intermediates. Ranolazine is an anti-ischemic agent which modulates myocardial metabolism.
Synonyms
1,2-Epoxy-3-(2-methoxyphenoxy)propane; 1,2-Epoxy-3-(o-methoxyphenoxy)propane; Glycidyl 2-Methoxyphenyl Ether; 1-(2-Methoxyphenoxy)-2,3-epoxypropane; NSC 112256; NSC 133442; Guaiacol glycidyl ether; Methoxyphenyl glycidyl ether; Ranolazine Impurity 6; Ranolazine USP Related Compound A
IUPAC Name
2-[(2-methoxyphenoxy)methyl]oxirane
Canonical SMILES
COC1=CC=CC=C1OCC2CO2
InChI
InChI=1S/C10H12O3/c1-11-9-4-2-3-5-10(9)13-7-8-6-12-8/h2-5,8H,6-7H2,1H3
InChI Key
RJNVSQLNEALZLC-UHFFFAOYSA-N
Boiling Point
152-158°C
Melting Point
33-36°C
Purity
96%
Density
1.142±0.06 g/cm3 (Predicted)
Solubility
Soluble in Chloroform, Methanol
Appearance
White to Off-white Low-melting Solid
Storage
Store at -20°C

Safety Information

Hazards
H315:
Causes skin irritation.
H319:
Causes serious eye irritation.
H341:
Suspected of causing genetic defects.
Precautionary Statement
P201:
Obtain special instructions before use.
P264:
Wash thoroughly after handling.
P280:
Wear protective gloves/protective clothing/eye protection/face protection.
P308+P313:
If exposed or concerned:
Get medical advice/attention.
P337+P313:
If eye irritation persists:
Get medical advice/attention.
P501:
Dispose of contents/container in accordance with local/regional/national/international regulations.

Computed Properties

XLogP3
1.6
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
3
Rotatable Bond Count
4
Exact Mass
180.078644241 g/mol
Monoisotopic Mass
180.078644241 g/mol
Topological Polar Surface Area
31Ų
Heavy Atom Count
13
Formal Charge
0
Complexity
160
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
1
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes

Patents

Publication Number Title Priority Date
CN-113387873-A Substituted diaryl compound, preparation method and application thereof 2021-06-15
WO-2022049070-A1 Electrically conductive epoxy resin coating and electrostatically dissipative floor 2020-09-01
WO-2022049071-A1 Transparent electrically conductive epoxy resin coating and electrostatic dissipative floor 2020-09-01
CN-111440131-A Method for refining easy-to-decompose guaiacol glycidyl ether 2020-04-27
CN-111440131-B Method for refining easy-to-decompose guaiacol glycidyl ether 2020-04-27
WO-2021170511-A1 Amine epoxy resin adduct 2020-02-24
WO-2021170512-A1 Amine-epoxy resin addition product 2020-02-24
WO-2021170513-A1 Curing agents for epoxy resin coatings 2020-02-24
CN-113045934-A Printing ink, application thereof and preparation method of quantum dot film 2019-12-28
WO-2021083744-A1 Impregnation resin for a woven or stitched fabric 2019-10-28

Literatures

PMID Publication Date Title Journal
5832 1975-01-01 [Effect of a new beta-sympatholytic agent for ICI 66 082 on hemodynamics and cardiac contraction without and with experimental coronary occlusion] Verhandlungen der Deutschen Gesellschaft fur Innere Medizin
The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Related Products

Online Inquiry
  • Verification code
USA
  • International:
  • US & Canada (Toll free):
  • Email:
  • Fax:
UK
  • Email:
Copyright © 2024 BOC Sciences. All rights reserved.
Inquiry Basket