Hydroxyethyl cellulose

Product Information

Description
Hydroxyethyl cellulose is a biopolymer often used as a thickener and adhesive.
Synonyms
Cellulose, 2-hydroxyethyl ether; Cellulose hydroxyethylate
Canonical SMILES
CC1C(C(C(C(O1)CO)OC2C(C(C(C(O2)COC3C(C(C(C(O3)CO)OC)O)O)OC4C(C(C(C(O4)CO)OC)O)OCCO)O)O)O)O
InChI
InChI=1S/C29H52O21/c1-10-15(34)16(35)24(13(8-33)45-10)49-28-20(39)18(37)25(50-29-26(43-5-4-30)21(40)23(42-3)12(7-32)47-29)14(48-28)9-44-27-19(38)17(36)22(41-2)11(6-31)46-27/h10-40H,4-9H2,1-3H3
InChI Key
CWSZBVAUYPTXTG-UHFFFAOYSA-N
Melting Point
288-290°C (dec.)
Flash Point
725 °F
Density
0.75 g/mL at 25°C(lit.)
Solubility
H2O: ≤5 wt. % at 20 °C
Appearance
White to off-white powder
Application
·Used as adhesives, bonding aids, filling cement admixtures
·Used as coatings and optical brightener additives, coating polymers, filter control additives
·Used as wet strength enhancer, protective colloid, rebound and slip reducing agent, rheology control modifier
·Used as a gelling and thickening agent in the development of biological structures for hydrophobic drugs
Storage
Store at room temperature
Grade
Reagent Grade
Stability
Stable. Incompatible with strong oxidizing agents, acid chlorides, acid anhydrides
LogP
0.35240

Safety Information

Hazards
Irritant
Handling
Gloves & fume hood
Molecular WeightViscosityDescription
~1,000,000 1% AQ = 1.500-2.500 cps Water-soluble cellulose ether, used as a binder and thickening agent. Powder
~90,000 5% AQ = 75-150 cps Water-soluble cellulose ether, used as a binder and thickening agent. Powder
~720,000 2% AQ = 4.500-6.500 cps Water-soluble cellulose ether, used as a binder and thickening agent. Powder

Computed Properties

XLogP3
-7.7
Hydrogen Bond Donor Count
11
Hydrogen Bond Acceptor Count
21
Rotatable Bond Count
15
Exact Mass
736.30010866 g/mol
Monoisotopic Mass
736.30010866 g/mol
Topological Polar Surface Area
315Ų
Heavy Atom Count
50
Formal Charge
0
Complexity
999
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
20
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes

Patents

Publication Number Title Priority Date
WO-2021086938-A1 Drip-free cleansing mask with enhanced active deposition 2019-10-30

Literatures

PMID Publication Date Title Journal
25735667 2015-04-30 Graphene-oxide stabilization in electrolyte solutions using hydroxyethyl cellulose for drug delivery application International journal of pharmaceutics
22795045 2012-10-01 Phase behavior and rheological properties of DNA-cationic polysaccharide mixtures Journal of colloid and interface science
22840013 2012-10-01 A versatile method for functionalization and grafting of 2-hydroxyethyl cellulose (HEC) via Click chemistry Carbohydrate polymers
22840022 2012-10-01 Preparation and characterization of poly(acrylic acid)-hydroxyethyl cellulose graft copolymer Carbohydrate polymers
22360941 2012-08-15 Development of liposome gel based formulations for intravaginal delivery of the recombinant HIV-1 envelope protein CN54gp140 European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences
22594324 2012-05-01 Enhanced viability of corneal epithelial cells for efficient transport/storage using a structurally modified calcium alginate hydrogel Regenerative medicine
22448630 2012-04-10 Dispersions of nanocrystalline cellulose in aqueous polymer solutions: structure formation of colloidal rods Langmuir : the ACS journal of surfaces and colloids
22155401 2012-04-01 Concentration selective hydration and phase states of hydroxyethyl cellulose (HEC) in aqueous solutions International journal of biological macromolecules
22310278 2012-03-16 Is pulsed electric field still effective for RNA separation in capillary electrophoresis? Journal of chromatography. A
21895999 2012-03-01 Effects of cationic hydroxyethyl cellulose on glucose metabolism and obesity in a diet-induced obesity mouse model Journal of diabetes
The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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