Metformin EP Impurity C

Inquiry

Molecular Formula:

C5H10N6

Molecular Weight:

154.17

CAS Number:

1985-46-2

Catalog Number:

1985-46-2

Product Information

Molecular Formula:

C5H10N6

Molecular Weight:

154.17

Description

Metformin EP Impurity C is an impurity of Metformin (HCl), an oral hypoglycemic agent that slows electron transport in the oxidation pathway in mitochondria.

Synonyms

Metformin USP Related Compound C; 2,4-Diamino-6-(dimethylamino)-s-triazine; 2-(Dimethylamino)-4,6-diamino-s-triazine; 2,4-Diamino-6-dimethylamino-1,3,5-triazine; N,N-Dimethyl-1,3,5-triazine-2,4,6-triamine; N2,N2-Dimethylmelamine

IUPAC Name

2-N,2-N-dimethyl-1,3,5-triazine-2,4,6-triamine

Canonical SMILES

CN(C)C1=NC(=NC(=N1)N)N

InChI

InChI=1S/C5H10N6/c1-11(2)5-9-3(6)8-4(7)10-5/h1-2H3,(H4,6,7,8,9,10)

InChI Key

IEFWDQQGFDLKFK-UHFFFAOYSA-N

Boiling Point

414.8±28.0 °C(Predicted)

Melting Point

>300°C (dec.)

Purity

> 95%

Density

1.380±0.06 g/cm3(Predicted)

Solubility

Soluble in Aqueous Acid (Slightly), DMSO (Slightly), Methanol (Very Slightly, Heated)

Appearance

White to Off-White Solid

Storage

Store at 2-8°C

Safety Information

Hazards

H315:
Causes skin irritation.
H319:
Causes serious eye irritation.

Precautionary Statement

P264:
Wash thoroughly after handling.
P280:
Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352:
IF ON SKIN:
Wash with plenty of soap and water.
P332+P313:
If skin irritation occurs:
Get medical advice/attention.
P337+P313:
If eye irritation persists:
Get medical advice/attention.
P362+P364:
Take off contaminated clothing. [As modified by IV ATP].
And wash it before reuse. [Added by IV ATP].

Computed Properties

XLogP3

0.4

Hydrogen Bond Donor Count

Hydrogen Bond Acceptor Count

Rotatable Bond Count

Exact Mass

154.09669434 g/mol

Monoisotopic Mass

154.09669434 g/mol

Topological Polar Surface Area

94Å²

Heavy Atom Count

Formal Charge

Complexity

116

Isotope Atom Count

Defined Atom Stereocenter Count

Undefined Atom Stereocenter Count

Defined Bond Stereocenter Count

Undefined Bond Stereocenter Count

Covalently-Bonded Unit Count

Compound Is Canonicalized

Yes

Patents

Publication Number	Title	Priority Date
CN-112058102-A	High-rejection-rate ultrafiltration membrane and preparation method thereof	2020-09-07
CN-112011267-A	Heat-preservation and heat-insulation coating and preparation method thereof	2020-09-07
CN-112011267-B	Heat-preservation and heat-insulation coating and preparation method thereof	2020-09-07
WO-2021161989-A1	Liquid crystal aligning agent, liquid crystal alignment film, liquid crystal display device, and diamine	2020-02-14
CN-110577644-A	preparation method of triazine polyimide capable of being coated	2019-09-17
WO-2020203110-A1	Liquid crystal aligning agent, liquid crystal alignment film, liquid crystal display element, and diamine	2019-03-29
TW-202104559-A	Liquid crystal alignment agent, liquid crystal alignment film, liquid crystal display element and diamine	2019-03-29
CN-113711117-A	Liquid crystal aligning agent, liquid crystal alignment film, liquid crystal display element, and diamine	2019-03-29
KR-20210145744-A	Liquid crystal aligning agent, liquid crystal aligning film, liquid crystal display element and diamine	2019-03-29
TW-202045697-A	Liquid crystal alignment agent, liquid crystal alignment film and liquid crystal display element using the same	2019-02-27

Literatures

PMID	Publication Date	Title	Journal
15134404	2004-01-01	[Occupational allergic contact dermatitis caused by dimethylmelamine resin in a textile worker]	Giornale italiano di medicina del lavoro ed ergonomia

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