Nickel(II) chloride ethylene glycol dimethyl ether complex

Product Information

Molecular Formula:
NiCl2:CH3OCH2CH2OCH3
Molecular Weight:
219.72
Description
Nickel(II) chloride ethylene glycol dimethyl ether complex can be used:• As a catalyst for the borylation of racemic benzylic chloride to synthesize enantioenriched benzylic boronic esters.• As a promoter for the trifluoromethylation of alkyl iodides to synthesize broad range of alkyl-CF3 compounds.• For the synthesis of nickel bis(benzimidazol-2-ylidene) pincer complexes which can be used for electrocatalytic reduction of CO2 to CO.• As a Lewis acid catalyst for C-acylation β-ketoesters through photoactivation by visible light.
Synonyms
Dichloro(dimethoxyethane)nickel,NiCl2 glyme
IUPAC Name
dichloronickel1,2-dimethoxyethane
Canonical SMILES
COCCOC.Cl[Ni]Cl
InChI
InChI=1S/C4H10O2.2ClH.Ni/c1-5-3-4-6-2/h3-4H2,1-2H32*1H/q+2/p-2
InChI Key
OCMNCWNTDDVHFK-UHFFFAOYSA-L
Melting Point
>300 °C
Flash Point
Not applicable
Purity
98%

Safety Information

Hazards
H261 - H301 - H315 - H319 - H334 - H350 - H400
Precautionary Statement
P201 - P231 + P232 - P273 - P301 + P310 + P330 - P302 + P352 - P305 + P351 + P338

Computed Properties

Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
2
Rotatable Bond Count
3
Exact Mass
217.941127 g/mol
Monoisotopic Mass
217.941127 g/mol
Topological Polar Surface Area
18.5Ų
Heavy Atom Count
9
Formal Charge
0
Complexity
20.3
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
2
Compound Is Canonicalized
Yes

Patents

Publication Number Title Priority Date
CN-113999131-A Method for preparing amide derivative by amination of alkyl C-H bond under catalysis of nickel promoted by visible light 2021-12-29
CN-114032567-A Electrochemical reduction carboxylation method based on non-sacrificial anode strategy 2021-11-23
CN-113666862-A Method for preparing chiral 3-nitroindole compound by nickel-catalyzed asymmetric nitration reaction 2021-08-18
CN-113754689-A Nickel-catalyzed asymmetric hydroamination method for olefin 2021-08-03
CN-113387876-A Nickel-catalyzed direct reduction cross-coupling method for heterocyclic phosphonium salt and aryl bromide and product 2021-07-21
CN-113480578-A (alpha-diimine) nickel complex compositions and uses thereof 2021-06-23
CN-113105444-A Chiral pyridine bisoxazoline ligand and preparation method and application thereof 2021-04-19
CN-112939750-A Method for transferring asymmetric functionalization by nickel-hydrogen catalysis olefin promoted by ligand relay strategy 2021-02-04
CN-112679290-A Nickel-catalyzed asymmetric hydrogen alkynylation method for olefins and application of nickel-catalyzed asymmetric hydrogen alkynylation method in preparation of AMG837 2021-01-04
CN-112679290-B Nickel-catalyzed asymmetric hydrogen alkynylation method for olefins and application of nickel-catalyzed asymmetric hydrogen alkynylation method in preparation of AMG837 2021-01-04
The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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