Nickel(II) chloride hydrate

Product Information

Molecular Formula:
NiCl2 · xH2O
Molecular Weight:
129.60 (anhydrous basis)
Description
Nickel(II) chloride hydrate is an esteemed chemical compound prevalent in the biomedical sphere and plays a pivotal catalytic function within diverse biological reactions. Remarkably, it boasts multifaceted prowess, encompassing the treatment of specific ailments like cancer and its indispensable role as a reagent in drug synthesis.
Synonyms
Nickel dichloride hydrate
IUPAC Name
dichloronickelhydrate
Canonical SMILES
O.Cl[Ni]Cl
InChI
InChI=1S/2ClH.Ni.H2O/h2*1H1H2/q+2/p-2
InChI Key
HGGYAQHDNDUIIQ-UHFFFAOYSA-L
Purity
99.95% trace metals basis

Safety Information

Hazards
H301 + H331 - H315 - H317 - H334 - H350i - H360D - H372 - H410
Precautionary Statement
P201 - P273 - P280 - P301 + P310 + P330 - P302 + P352 - P304 + P340 + P311

Computed Properties

Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
1
Rotatable Bond Count
0
Exact Mass
145.883612 g/mol
Monoisotopic Mass
145.883612 g/mol
Topological Polar Surface Area
1Ų
Heavy Atom Count
4
Formal Charge
0
Complexity
2.8
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
2
Compound Is Canonicalized
Yes

Patents

Publication Number Title Priority Date
CN-113955814-A NiCl synthesized at low temperature2Powder and use 2021-11-30
CN-113831535-A Preparation method of polyarylethersulfone resin, polyarylethersulfone resin obtained by preparation method and application of polyarylethersulfone resin 2021-09-29
CN-113913016-A Polyarylethersulfone composition and preparation method and application thereof 2021-09-29
CN-113457740-A Catalyst for preparing ethanol by catalytic hydrogenation of methyl acetate and preparation method thereof 2021-05-31
CN-113445087-A Preparation method of environment-friendly high-strength corrosion-resistant aluminum alloy 2021-05-13
CN-112375082-A Series of carbazole derivatives and application thereof 2020-11-23
CN-112521343-A Organic electroluminescent material and device thereof 2020-11-23
CN-112086289-A Sunlight-driven electricity-oxygen co-production seawater battery and preparation method thereof 2020-08-12
KR-20200080212-A Light-emitting device comprising perovskite-organic small molecule-mixed light-emitting layer and preparation method thereof 2020-06-26
KR-102285319-B1 Catalysts for hydrogen evolution reaction including rhodium-nickel alloy nanofibers and method of preparing rhodium-nickel alloy nanofibers 2019-12-17

Literatures

PMID Publication Date Title Journal
34571076 2021-11-01 Nickel chloride regulates ANGPTL4 via the HIF-1α-mediated TET1 expression in lung cells Toxicology letters
33596451 2021-04-15 Lactate released from human fibroblasts enhances Ni elution from Ni plate Toxicology
30724446 2019-05-01 Nickel-induced VEGF expression via regulation of Akt, ERK1/2, NFκB, and AMPK pathways in H460 cells Environmental toxicology
29355601 2018-02-15 Nickel ions bind to HSP90β and enhance HIF-1α-mediated IL-8 expression Toxicology
26004978 2015-08-06 Further development of the theory and mathematical description of combined toxicity: An approach to classifying types of action of three-factorial combinations (a case study of manganese-chromium-nickel subchronic intoxication) Toxicology
24158569 2014-04-01 Nickel induces interleukin-1β secretion via the NLRP3-ASC-caspase-1 pathway Inflammation
24448832 2014-04-01 Nickel-induced cell death and survival pathways in cultured renal proximal tubule cells: roles of reactive oxygen species, ceramide and ABCB1 Archives of toxicology
24612858 2014-03-10 Whole adult organism transcriptional profiling of acute metal exposures in male zebrafish BMC pharmacology & toxicology
24577088 2014-02-27 MiRNA-210 modulates a nickel-induced cellular energy metabolism shift by repressing the iron-sulfur cluster assembly proteins ISCU1/2 in Neuro-2a cells Cell death & disease
23792913 2013-09-01 Synthesis, structure and antifungal activity of thiophene-2,3-dicarboxaldehyde bis(thiosemicarbazone) and nickel(II), copper(II) and cadmium(II) complexes: unsymmetrical coordination mode of nickel complex Journal of inorganic biochemistry
The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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