Tri(o-tolyl)phosphine

Product Information

Molecular Formula:
C21H21P
Molecular Weight:
304.37
Description
Ligand used in a ruthenium-catalyzed direct amination of alcohols.
Synonyms
tris(2-methylphenyl)phosphine; tris(2-methylphenyl)phosphane
IUPAC Name
tris(2-methylphenyl)phosphane
Canonical SMILES
CC1=CC=CC=C1P(C2=CC=CC=C2C)C3=CC=CC=C3C
InChI
InChI=1S/C21H21P/c1-16-10-4-7-13-19(16)22(20-14-8-5-11-17(20)2)21-15-9-6-12-18(21)3/h4-15H,1-3H3
InChI Key
COIOYMYWGDAQPM-UHFFFAOYSA-N
Melting Point
123-125 °C (lit.)
Purity
97 %
Appearance
Beige crystalline solid
LogP
4.37000

Safety Information

Precautionary Statement
P261, P264, P271, P273, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P391, P403+P233, P405, and P501
Signal Word
Warning

Computed Properties

XLogP3
5.7
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
0
Rotatable Bond Count
3
Exact Mass
304.138087668 g/mol
Monoisotopic Mass
304.138087668 g/mol
Topological Polar Surface Area
0Ų
Heavy Atom Count
22
Formal Charge
0
Complexity
287
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes

Patents

Publication Number Title Priority Date
JP-2022037094-A Method for producing a polyene compound having a hydroxyl group 2021-12-14
CN-114163445-A Raatinib intermediate and preparation method thereof 2021-12-06
CN-113980044-A Preparation method of Ir-O-P type catalyst diboronic acid/ester compound 2021-12-03
CN-113980250-A Conjugated polymer material capable of being processed by green solvent and preparation method thereof 2021-11-20
CN-113861156-A Near-infrared aggregation-induced emission organic fluorescent dye and preparation method and application thereof 2021-11-01
CN-113881020-A Electrochromic material with double triphenylamine structure and preparation method and application thereof 2021-10-29
CN-114015021-A Terminal functional side chain substituted pyrrolopyrroledione-based terpolymer and preparation method and application thereof 2021-10-28
CN-113896865-A Naphthalimide polymer semiconductor containing dopamine-derived side chain and preparation method thereof 2021-10-21
CN-113801302-A Non-conjugated polymer based on A-D-A' -D-A type indacenothiophene derivative unit and preparation method thereof 2021-10-18
CN-113698581-A Benzothiadiazole polymer with perylene diimide as suspension receptor and preparation method thereof 2021-10-13

Literatures

PMID Publication Date Title Journal
22829528 2012-09-03 Effects of phosphorus substituents on reactions of α-alkoxyphosphonium salts with nucleophiles Chemistry (Weinheim an der Bergstrasse, Germany)
22618248 2012-07-07 Mechanochemical and solution synthesis, X-ray structure and IR and 31P solid state NMR spectroscopic studies of copper(I) thiocyanate adducts with bulky monodentate tertiary phosphine ligands Dalton transactions (Cambridge, England : 2003)
21863787 2011-10-07 Palladium-catalyzed cross-coupling of sterically demanding boronic acids with α-bromocarbonyl compounds The Journal of organic chemistry
21364596 2011-04-01 Synthesis and antibacterial activity of 2, 3-dehydro-3-O-(3-aryl-E-prop-2-enyl)-10, 11-anhydroclarithromycin derivatives The Journal of antibiotics
20610167 2010-07-01 Imaging of I2-imidazoline receptors by small-animal PET using 2-(3-fluoro-[4-11C]tolyl)-4,5-dihydro-1H-imidazole ([11C]FTIMD) Nuclear medicine and biology
20449525 2010-06-14 Remarkable effect of phosphine on the reactivity of O,P-acetal--efficient substitution reaction of O,P-acetal Chemical communications (Cambridge, England)
20023954 2010-01-07 Synthesis of InP nanofibers from tri(m-tolyl)phosphine: an alternative route to metal phosphide nanostructures Dalton transactions (Cambridge, England : 2003)
17044108 2007-01-01 Palladium-catalyzed intramolecular C(sp(3))--H functionalization: catalyst development and synthetic applications Chemistry (Weinheim an der Bergstrasse, Germany)
15824787 2005-04-21 Bulky triarylarsines are effective ligands for palladium catalysed Heck olefination Dalton transactions (Cambridge, England : 2003)
15631454 2005-01-12 Palladium-catalyzed intramolecular coupling between aryl iodides and allyl moieties via thermal and microwave-assisted conditions Journal of the American Chemical Society
The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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