Tributyrin

Catalog Number Size Price Stock Quantity
B1370-293891 5 kg $420 In stock
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Product Information

Molecular Formula:
C15H26O6
Molecular Weight:
302.36
Description
Tributyrin is a triglyceride existing in butter. Tributyrin is a prodrug of butyric acid to enhance antiproliferative effects of dihydroxycholecalciferol in human colon cancer cells, and it is used to identify the bacterium Moraxella catarrhalis in microbiological laboratories.
Synonyms
Glycerol tributyrate; Glyceryl tributyrate; Propane-1,2,3-triyl tributyrate; Butyrin; Butyryl triglyceride
IUPAC Name
2,3-di(butanoyloxy)propyl butanoate
Canonical SMILES
CCCC(=O)OCC(COC(=O)CCC)OC(=O)CCC
InChI
InChI=1S/C15H26O6/c1-4-7-13(16)19-10-12(21-15(18)9-6-3)11-20-14(17)8-5-2/h12H,4-11H2,1-3H3
InChI Key
UYXTWWCETRIEDR-UHFFFAOYSA-N
Boiling Point
190 °C / 15 mmHg
Melting Point
-75 °C
Flash Point
180 °C
Purity
95%
Density
1.04 g/cm3
Solubility
Sol in acetone, Benzene
Appearance
Liquid
Refractive Index
1.44
LogP
2.38490
Vapor Pressure
1.3X10-3 mm Hg at 25 °C
Henry's Law Constant
9.6X10-9 atm cu m/mole at 25 °C /Estimated/
Decomposition
When heated to decomposition it emits acrid smoke and fumes
Odor
FRUITY, BUTTERY

Computed Properties

XLogP3
2.4
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
6
Rotatable Bond Count
14
Exact Mass
302.17293854 g/mol
Monoisotopic Mass
302.17293854 g/mol
Topological Polar Surface Area
78.9Ų
Heavy Atom Count
21
Formal Charge
0
Complexity
304
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes

Patents

Publication Number Title Priority Date
CN-114181874-A Deep-sea micro bacillus and application thereof in enhancing flavor of aquatic seasoning 2022-02-16
CN-114181922-A Recombinant esterase, gene, recombinant bacterium and application of recombinant esterase to degradation of phthalate 2021-12-10
CN-114041542-A Feed additive for promoting piglet gastrointestinal health and preparation method thereof 2021-12-08
CN-113913347-A Paenibacillus balun TZ-1 and application thereof 2021-11-24
CN-114027414-A Traditional Chinese medicine esterase composition for laying hens and application thereof 2021-11-20
CN-114027097-A Mushroom culture medium containing nut green seedcase and preparation method thereof 2021-11-19
CN-113843549-A Silver soldering paste sintering aid and preparation method and application thereof 2021-11-18
CN-114107250-A Lipase CALBgold and preparation method and application thereof 2021-11-18
CN-114081990-A Traditional Chinese medicine composite temperature-sensitive gel embolic agent as well as preparation method and application thereof 2021-11-17
CN-113999793-A Lactobacillus plantarum with good fermentation characteristics and fragrance production function and screening method thereof 2021-11-12

Literatures

PMID Publication Date Title Journal
30503584 2019-01-15 Enhancement of mouse contact hypersensitivity appears with a short chain triacylglycerol but not with a long chain one Toxicology
29198882 2018-03-01 Adjuvant effect of short chain triacylglycerol tributyrin on a mouse contact hypersensitivity model Toxicology letters
21940155 2012-08-01 Chemopreventive effects of the dietary histone deacetylase inhibitor tributyrin alone or in combination with vitamin A during the promotion phase of rat hepatocarcinogenesis The Journal of nutritional biochemistry
22621868 2012-07-15 Tributyrin attenuates obesity-associated inflammation and insulin resistance in high-fat-fed mice American journal of physiology. Endocrinology and metabolism
22362134 2012-06-01 Modulation of histone deacetylase attenuates naloxone-precipitated opioid withdrawal syndrome Naunyn-Schmiedeberg's archives of pharmacology
22405988 2012-05-30 Dual function of tributyrin emulsion: solubilization and enhancement of anticancer effect of celecoxib International journal of pharmaceutics
22426713 2012-01-01 High-throughput screening method for lipases/esterases Methods in molecular biology (Clifton, N.J.)
22426724 2012-01-01 Purification, biochemical and kinetic properties of recombinant Staphylococcus aureus lipase Methods in molecular biology (Clifton, N.J.)
22426727 2012-01-01 Molecular modeling of lipase binding to a substrate-water interface Methods in molecular biology (Clifton, N.J.)
22082136 2011-12-14 Enzymatically catalyzed synthesis of low-calorie structured lipid in a solvent-free system: optimization by response surface methodology Journal of agricultural and food chemistry
The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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