Tris(4-methoxyphenyl)phosphine

Product Information

Molecular Formula:
C21H21O3P
Molecular Weight:
352.36
Description
Tris(4-methoxyphenyl)phosphine (CAS# 855-38-9) is a useful intermediate employed in organic synthesis and in other chemical processes.
Synonyms
tris(4-methoxyphenyl)phosphine; tris(4-methoxyphenyl)phosphane
IUPAC Name
tris(4-methoxyphenyl)phosphane
Canonical SMILES
COC1=CC=C(C=C1)P(C2=CC=C(C=C2)OC)C3=CC=C(C=C3)OC
InChI
InChI=1S/C21H21O3P/c1-22-16-4-10-19(11-5-16)25(20-12-6-17(23-2)7-13-20)21-14-8-18(24-3)9-15-21/h4-15H,1-3H3
InChI Key
UYUUAUOYLFIRJG-UHFFFAOYSA-N
Melting Point
131-134 °C
Purity
95 %
Appearance
White to yellow to orange powder to crystal
LogP
3.47060

Safety Information

Hazards
H315 H319 H335
Precautionary Statement
P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501
Signal Word
Warning

Computed Properties

XLogP3
4.5
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
3
Rotatable Bond Count
6
Exact Mass
352.12283153 g/mol
Monoisotopic Mass
352.12283153 g/mol
Topological Polar Surface Area
27.7Ų
Heavy Atom Count
25
Formal Charge
0
Complexity
310
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes

Patents

Publication Number Title Priority Date
CN-113816878-A Preparation method of 3-butene-1-sulfonyl fluoride compound 2021-11-02
CN-113698431-A Synthesis method of phosphine (III) compound 2021-09-27
CN-113831272-A Method for synthesizing 2-substituted indole compound by using palladium to catalyze iodobenzene and oxime ester 2021-09-26
CN-113801310-A Three-component catalytic initiation system catalyst and application thereof 2021-09-24
CN-113429286-A Method for synthesizing polysubstituted biaryl derivative by using aryl diazonium salt 2021-08-04
CN-113461590-A Method for constructing 1-substituted cyclopropane compound by virtue of phosphine-catalyzed C-H activated amination reaction of cyclopropane 2021-06-15
CN-113224313-A Metal organic phosphine frame glass modified metal negative current collector and preparation method thereof 2021-04-30
CN-113105374-A Method for synthesizing alkylamine derivative 2021-04-14
CN-113024556-A Preparation method of fused ring compound containing indole skeleton 2021-04-01
CN-113024556-B Preparation method of fused ring compound containing indole skeleton 2021-04-01

Literatures

PMID Publication Date Title Journal
22169871 2011-12-04 Three-component reaction discovery enabled by mass spectrometry of self-assembled monolayers Nature chemistry
22199512 2011-12-01 trans-Carbonyl-chloridobis[tris-(4-meth-oxy-phen-yl)phosphane-κP]rhodium(I) Acta crystallographica. Section E, Structure reports online
21341814 2011-03-18 Application of Mitsunobu reagents to redox isomerization of CF3-containing propargylic alcohols to (E)-α,β-enones The Journal of organic chemistry
21588847 2010-10-20 trans-Dichlorido-bis-[tris(4-meth-oxy-phenyl)-phosphane]palladium(II) toluene solvate Acta crystallographica. Section E, Structure reports online
21578578 2009-11-07 trans-Dichloridobis[tris-(4-methoxy-phen-yl)phosphine]palladium(II) benzene monosolvate Acta crystallographica. Section E, Structure reports online
21201372 2008-01-30 Dichlorido(η-toluene)[tris-(4-methoxy-phen-yl)phosphine]ruthenium(II) Acta crystallographica. Section E, Structure reports online
21200642 2007-12-06 μ(3)-Iodo-tri-μ(3)-sulfido-sulfidotris[tris-(4-methoxy-phen-yl)phosphine-κP]tri-copper(I)tungsten(VI) N,N-dimethyl-formide solvate Acta crystallographica. Section E, Structure reports online
11700121 2001-11-15 Reaction of arylphosphines with singlet oxygen: intra- vs intermolecular oxidation Organic letters
The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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