3-[Tris(trimethylsiloxy)silyl]propyl methacrylate

Product Information

Molecular Formula:
C16H38O5Si4
Molecular Weight:
422.81
Description
3-[Tris(trimethylsiloxy)silyl]propyl methacrylate is a key intermediate in the biomedical field and is frequently employed in drug delivery platforms and tissue regeneration mechanisms. It plays an important role in controlling drug emissions and can be widely used in the development of therapeutic drugs for diseases such as malignant tumors, infections, and inflammatory abnormalities.
Synonyms
TRIS(TRIMETHYLSILOXY)-3-METHACRYLOXYPROPYLSILANE; 3-METHACRYLOXYPROPYLTRIS(TRIMETHYLSILOXY)SILANE; 3-(METHACRYLOYLOXY)PROPYLTRIS(TRIMETHYLSILOXY)SILANE; 3-METHACRYLOYLOXYPROPYLTRIS-(TRIMETHYLSILYLOXY)-SILAN; 3-(METHACRYLOYLOXY)PROPYLTRIS(TRIMETHYLSILYLOXY)SI
IUPAC Name
3-tris(trimethylsilyloxy)silylpropyl 2-methylprop-2-enoate
Canonical SMILES
CC(=C)C(=O)OCCC[Si](O[Si](C)(C)C)(O[Si](C)(C)C)O[Si](C)(C)C
InChI
InChI=1S/C16H38O5Si4/c1-15(2)16(17)18-13-12-14-25(19-22(3,4)5,20-23(6,7)8)21-24(9,10)11/h1,12-14H2,2-11H3
InChI Key
BESKSSIEODQWBP-UHFFFAOYSA-N
Boiling Point
112-115ºC (0.2 mmHg)
Flash Point
200 ℃
Purity
>96.0%(GC)
Density
0.918
Appearance
Colorless transparent liquid
Storage
below 5ºC

Safety Information

Hazards
H315:
Causes skin irritation.
H319:
Causes serious eye irritation.
Precautionary Statement
P264:
Wash thoroughly after handling.
P280:
Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352:
IF ON SKIN:
Wash with plenty of soap and water.
P332+P313:
If skin irritation occurs:
Get medical advice/attention.
P337+P313:
If eye irritation persists:
Get medical advice/attention.
P362+P364:
Take off contaminated clothing. [As modified by IV ATP].
And wash it before reuse. [Added by IV ATP].

Computed Properties

Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
5
Rotatable Bond Count
12
Exact Mass
422.17963045 g/mol
Monoisotopic Mass
422.17963045 g/mol
Topological Polar Surface Area
54Ų
Heavy Atom Count
25
Formal Charge
0
Complexity
420
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes

Patents

Publication Number Title Priority Date
CN-113956422-A Silane modified acrylate polymer, preparation method and application thereof, acrylate polymer coating and application thereof 2021-11-12
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CN-113912775-A Indicator material and preparation method and application thereof 2021-11-03
CN-113968979-A Silicone hydrogel for contact lenses and method for producing same 2021-09-16
CN-113774651-A Surface modification method for liquid crystal polymer material 2021-09-14
CN-113861526-A High-wear-resistance low-heat-generation carbon black master batch and preparation method thereof 2021-09-07
CN-113717658-A Anti-aging white packaging adhesive film and preparation process thereof 2021-08-24
CN-113717334-A High-oxygen-transmission-rate corneal contact lens and preparation method thereof 2021-07-06
CN-113387667-A Impervious cement mortar and application thereof 2021-07-01
CN-113307916-A Silsesquioxane modified acrylate flame-retardant toughening agent and preparation method thereof 2021-06-22

Literatures

PMID Publication Date Title Journal
21750182 2012-11-01 Hyaluronic acid as an internal wetting agent in model DMAA/TRIS contact lenses Journal of biomaterials applications
20803455 2003-09-01 Bioactive polymers grafted on silicone to prevent Staphylococcus aureus prosthesis adherence: in vitro and in vivo studies Journal of applied biomaterials & biomechanics : JABB
The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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