Chitosan

Catalog Number Size Price Stock Quantity
B1370-187887 1kg $299 In stock
B1370-187887 10 kg $990 In stock
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Product Information

Molecular Formula:
[C7H15NO4]n
Molecular Weight:
60-120 kDa
Description
Chitosan is a deacetylated derivative of chitin. Chitosan is a polysaccharide present in the exoskeleton of a variety of crustaceans and cell walls of fungi. It can be used in the medical field and cosmetics manufacturing. In addition to its role in drug delivery, chitosan can also act as an adjuvant due to its immune-stimulating activity. Chitosan stimulates the immune system by activating the NLRP3 inflammasome, which produces potent IL-1b. When tested in an experimental model of vaccination, chitosan elicits a balanced Th1/Th2 response. Nutritional supplement in health care products.
Synonyms
Deacetylated chitin; Poly(D-glucosamine); Poly-b-(1,4)-2-Amino-2-deoxy-D-glucose; 2-Amino-2-deoxy-(1,4)-b-D-glucopyranan; deacetylchitin; b-1,4-poly-D-glucosamine; poly-D-glucosamine; poly-(1,4-b-D-glucopyranosamine)
Melting Point
>226°C (dec.)
Purity
DAC degree:90%+
Density
1.35-1.40 g/cm3
Solubility
Soluble in 1M Acetic Acid (10 mg/ml); Insoluble in Water
Appearance
White to Off-white Powder
Application
Ingredient of health care products.
Storage
Store at 2-8°C
Refractive Index
1.7
Viscosity
1% solution >90 cPs
Stability
Stable. Incompatible with strong oxidizing agents.
LogP
-1.52550

Safety Information

Hazards
Harmless-use normal precautions
Handling
Exercise normal care

Computed Properties

XLogP3
-21.4
Hydrogen Bond Donor Count
29
Hydrogen Bond Acceptor Count
47
Rotatable Bond Count
27
Exact Mass
1525.6353145 g/mol
Monoisotopic Mass
1525.6353145 g/mol
Topological Polar Surface Area
808Ų
Heavy Atom Count
104
Formal Charge
0
Complexity
2630
Isotope Atom Count
0
Defined Atom Stereocenter Count
45
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes

Patents

Publication Number Title Priority Date
CN-114163549-A Chitosan oligosaccharide and bivalent plant vaccine covalent conjugate and preparation method and application thereof 2022-01-06
CN-114134708-A One-bath one-step dyeing and antibacterial finishing method for wool 2021-12-29
CN-114129215-A Portable hemostatic device and method of use 2021-12-03
CN-114015108-A Crude tea extract/chitosan oligosaccharide nanoparticle effervescent cream material, preparation method and application 2021-12-01
CN-114027402-A Anti-stress feed additive based on purification chelation process and preparation method and application thereof 2021-11-29
CN-114031650-A Chitosan oligosaccharide selenium coordination compound and preparation method and application thereof 2021-11-29
CN-114099787-A Absorbable biological membrane, preparation method and application thereof 2021-11-29
CN-114058659-A Preparation method of chitin oligosaccharide 2021-11-17
CN-113736718-A Enzyme production method and application thereof in producing amino-oligosaccharin with specific molecular segment through enzymolysis 2021-11-08
CN-113736718-B Enzyme production method and application thereof in producing amino-oligosaccharin with specific molecular segment through enzymolysis 2021-11-08

Literatures

PMID Publication Date Title Journal
35961540 2022-09-25 Cromolyn chitosan nanoparticles reverse the DNA methylation of RASSF1A and p16 genes and mitigate DNMT1 and METTL3 expression in breast cancer cell line and tumor xenograft model in mice Chemico-biological interactions
35513110 2022-07-01 Insights overview on the possible protective effect of chitosan nanoparticles encapsulation against neurotoxicity induced by carbendazim in rats Neurotoxicology
34874108 2022-03-01 Chitosan attenuated the neurotoxicity-induced titanium dioxide nanoparticles in brain of adult rats Environmental toxicology
31931169 2020-03-01 Multifunctional carboxymethyl chitosan derivatives-layered double hydroxide hybrid nanocomposites for efficient drug delivery to the posterior segment of the eye Acta biomaterialia
31590850 2020-01-01 Functional chitosan oligosaccharide nanomicelles for topical ocular drug delivery of dexamethasone Carbohydrate polymers
30928397 2019-05-25 Chitosan oligosaccharides prevent doxorubicin-induced oxidative stress and cardiac apoptosis through activating p38 and JNK MAPK mediated Nrf2/ARE pathway Chemico-biological interactions
30041514 2019-01-01 Anti-Mucin1 Aptamer-Conjugated Chitosan Nanoparticles for Targeted Co-Delivery of Docetaxel and IGF-1R siRNA to SKBR3 Metastatic Breast Cancer Cells Iranian biomedical journal
28961808 2018-01-24 Oral Delivery of Nanoparticles Loaded With Ginger Active Compound, 6-Shogaol, Attenuates Ulcerative Colitis and Promotes Wound Healing in a Murine Model of Ulcerative Colitis Journal of Crohn's & colitis
29491707 2018-01-01 Functional intercalated nanocomposites with chitosan-glutathione-glycylsarcosine and layered double hydroxides for topical ocular drug delivery International journal of nanomedicine
28987369 2017-10-01 The regulatory effects of fish oil and chitosan on hepatic lipogenic signals in high-fat diet-induced obese rats Journal of food and drug analysis
The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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