N-Acryloyloxysuccinimide

Inquiry

Molecular Formula:

C7H7NO4

Molecular Weight:

169.13

CAS Number:

38862-24-7

Catalog Number:

38862-24-7

Product Information

Molecular Formula:

C7H7NO4

Molecular Weight:

169.13

Description

N-Acryloyloxysuccinimide is a pivotal compound in biomedical research that exhibits exceptional versatility as a reagent for synthesizing diverse polymers. This uniqueness allows for the precise and controlled release of therapeutic drugs specifically in targeted systems. Remarkably, N-Acryloyloxysuccinimide plays a crucial and essential role in the advancement of drug delivery systems catering to the treatment of cancer, infectious diseases, and inflammatory conditions.

Synonyms

N-ACRYLOXYSUCCINIMIDE; ACRYLIC ACID N-HYDROXY-SUCCINIMIDE ESTER; AKOS MSC-0123; 1-[(1-OXO-2-PROPENYL)OXY]-2,5-PYRROLIDINEDIONE; 1-(ACRYLOYLOXY)-2,5-PYRROLIDINEDIONE; N-Acryloxysuccinimide (NAS); N-SucciniMidyl Acrylate; Acrylic Acid N-Succinimidyl Ester; 2,5-Dioxopyrrolidin-1-yl acrylate

IUPAC Name

(2,5-dioxopyrrolidin-1-yl) prop-2-enoate

Canonical SMILES

C=CC(=O)ON1C(=O)CCC1=O

InChI

InChI=1S/C7H7NO4/c1-2-7(11)12-8-5(9)3-4-6(8)10/h2H,1,3-4H2

InChI Key

YXMISKNUHHOXFT-UHFFFAOYSA-N

Boiling Point

251.3 °C at 760 mmHg

Melting Point

69 °C

Purity

> 98% (GC)

Density

1.340 g/cm3

Appearance

White to yellow-brown powder

Storage

2-8 °C

Refractive Index

1.5500 (estimate)

Safety Information

Hazards

H315:
Causes skin irritation.
H319:
Causes serious eye irritation.

Precautionary Statement

P264:
Wash thoroughly after handling.
P280:
Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352:
IF ON SKIN:
Wash with plenty of soap and water.
P332+P313:
If skin irritation occurs:
Get medical advice/attention.
P337+P313:
If eye irritation persists:
Get medical advice/attention.
P362+P364:
Take off contaminated clothing. [As modified by IV ATP].
And wash it before reuse. [Added by IV ATP].

Computed Properties

XLogP3

-0.2

Hydrogen Bond Donor Count

Hydrogen Bond Acceptor Count

Rotatable Bond Count

Exact Mass

169.03750770 g/mol

Monoisotopic Mass

169.03750770 g/mol

Topological Polar Surface Area

63.7Å²

Heavy Atom Count

Formal Charge

Complexity

242

Isotope Atom Count

Defined Atom Stereocenter Count

Undefined Atom Stereocenter Count

Defined Bond Stereocenter Count

Undefined Bond Stereocenter Count

Covalently-Bonded Unit Count

Compound Is Canonicalized

Yes

Patents

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CN-113599507-A	Preparation method of glucose-triggered active oxygen response injection type composite hydrogel	2021-08-11

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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