N-Succinimidyl Methacrylate

Product Information

Molecular Formula:
C8H9NO4
Molecular Weight:
183.16
Description
Methacrylic acid N-hydroxysuccinimide ester can be copolymerized by reversible addition fragmentation chain transfer (RAFT) polymerization for bioconjugation with proteins. It can be used in the fabrication of a bionanocomposite for the removal of chromium from water. It can be copolymerized with poly(N-isopropylacrylamide) for potential usage in immunoassay, catalyst recovery and drug delivery.
Synonyms
Methacrylic Acid N-Succinimidyl Ester
IUPAC Name
(2,5-dioxopyrrolidin-1-yl) 2-methylprop-2-enoate
Canonical SMILES
CC(=C)C(=O)ON1C(=O)CCC1=O
InChI
InChI=1S/C8H9NO4/c1-5(2)8(12)13-9-6(10)3-4-7(9)11/h1,3-4H2,2H3
InChI Key
ACGJEMXWUYWELU-UHFFFAOYSA-N
Boiling Point
270.1±23.0 °C(Predicted)
Melting Point
102.0 to 106.0 °C
Purity
>98.0%(N)
Density
1.29±0.1 g/cm3(Predicted)
Appearance
White to Almost white powder to crystal
Storage
0-10°C

Safety Information

Hazards
H315:
Causes skin irritation.
H319:
Causes serious eye irritation.
Precautionary Statement
P264:
Wash thoroughly after handling.
P280:
Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352:
IF ON SKIN:
Wash with plenty of soap and water.
P332+P313:
If skin irritation occurs:
Get medical advice/attention.
P337+P313:
If eye irritation persists:
Get medical advice/attention.
P362+P364:
Take off contaminated clothing. [As modified by IV ATP].
And wash it before reuse. [Added by IV ATP].

Computed Properties

XLogP3
0.2
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
4
Rotatable Bond Count
3
Exact Mass
183.05315777 g/mol
Monoisotopic Mass
183.05315777 g/mol
Topological Polar Surface Area
63.7Ų
Heavy Atom Count
13
Formal Charge
0
Complexity
279
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes

Patents

Publication Number Title Priority Date
CN-114085317-A Reactive UCST copolymer and preparation method thereof 2021-12-22
CN-112979968-B Cartilage targeting zwitterionic polymer and preparation method and application thereof 2021-04-16
CN-112812228-A UCST enhanced acrylamide copolymer and preparation method thereof 2021-01-22
CN-112876688-A Preparation method of nano micelle suitable for tandem catalysis 2021-01-20
KR-20220015844-A Fluorescent magnetic nanoparticles using porous silica and preparation method thereof 2020-07-31
US-2022031914-A1 Antimicrobial Coatings 2020-07-30
WO-2022026689-A1 Antimicrobial coatings 2020-07-30
CN-111925707-A Self-cleaning flame-retardant corrosion-resistant fluorine-silicon powder coating 2020-07-22
CN-111925707-B Self-cleaning flame-retardant corrosion-resistant fluorine-silicon powder coating 2020-07-22
WO-2022010850-A1 Polymeric carriers for delivery of therapeutic agents 2020-07-06
The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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