N-tert-Butylacrylamide

Product Information

Molecular Formula:
C7H13NO
Molecular Weight:
127.18
Description
N-tert-Butylacrylamide is a paramount compound that extensively employed in the realm of biomedical research. Garnering recognition for its exceptional attributes, this compound intricately contributes to the synthesis of sundry pharmaceuticals and substances. Its pivotal role in crafting targeted drug delivery systems for combating formidable ailments, including cancer, accentuates its promising prospects in the expansive horizon of biomedicine.
Synonyms
TBA; N-T-BUTYLACRYLAMIDE; N-TERT-BUTYLACRYLAMIDE; N-ACRYLOYL-TERT-BUTYLAMINE; TIMTEC-BB SBB008122; Acrylamide, N-tert-butyl-; n-(1,1-dimethylethyl)-2-propenamid; N-(1,1-dimethylethyl)-2-Propenamide
IUPAC Name
N-tert-butylprop-2-enamide
Canonical SMILES
CC(C)(C)NC(=O)C=C
InChI
InChI=1S/C7H13NO/c1-5-6(9)8-7(2,3)4/h5H,1H2,2-4H3,(H,8,9)
InChI Key
XFHJDMUEHUHAJW-UHFFFAOYSA-N
Boiling Point
233.5ºC at 760mmHg
Melting Point
128-130ºC
Purity
95%
Density
0.876g/cm3
Appearance
white to off-white powder or chunks
Storage
0-6ºC
Refractive Index
1.4830 (estimate)

Safety Information

Hazards
H302:
Harmful if swallowed.
H315:
Causes skin irritation.
H319:
Causes serious eye irritation.
Precautionary Statement
P264:
Wash thoroughly after handling.
P270:
Do not eat, drink or smoke when using this product.
P280:
Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312+P330:
IF SWALLOWED:
Call a POISON CENTER or doctor/physician if you feel unwell.
Rinse mouth.
P337+P313:
If eye irritation persists:
Get medical advice/attention.
P501:
Dispose of contents/container in accordance with local/regional/national/international regulations.

Computed Properties

XLogP3
1.1
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
1
Rotatable Bond Count
2
Exact Mass
127.099714038 g/mol
Monoisotopic Mass
127.099714038 g/mol
Topological Polar Surface Area
29.1Ų
Heavy Atom Count
9
Formal Charge
0
Complexity
121
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes

Patents

Publication Number Title Priority Date
CN-114149788-A Slow-release ice and snow melting agent, preparation method thereof and thin-layer cover material containing slow-release ice and snow melting agent 2021-12-29
CN-113980175-A Preparation method of modified hydrolyzed polymaleic anhydride 2021-12-27
CN-114053879-A Preparation method of potassium ion exchange membrane 2021-12-16
CN-114058450-A Stable granular detergent composition and preparation method thereof 2021-12-03
CN-114149868-A Tablet detergent composition with hardness and solubility and preparation method thereof 2021-12-03
CN-113912773-A Amide polycarboxylic acid water treatment agent, preparation method and application thereof, composite silicon scale-resistant water treatment agent and use method thereof 2021-11-29
CN-114014994-A Resistance reducing agent capable of mixing and adjusting viscosity on line, resistance reducing type fracturing fluid and preparation method thereof 2021-11-19
CN-113897189-A Jelly glue system suitable for high-temperature high-salinity fracture-cavity oil reservoir profile control and application 2021-11-18
CN-114044862-A Preparation method of chitin brush-shaped conductive elastomer material and prepared material 2021-11-15
JP-2022010263-A Membrane filtration device 2021-11-12

Literatures

PMID Publication Date Title Journal
22616950 2012-06-11 Simultaneous enhancement of cell proliferation and thermally induced harvest efficiency based on temperature-responsive cationic copolymer-grafted microcarriers Biomacromolecules
22525873 2012-06-01 Removal of potentially genotoxic acetamide and arylsulfonate impurities from crude drugs by molecular imprinting Journal of chromatography. A
22168533 2012-01-24 The effect of nanoparticles on amyloid aggregation depends on the protein stability and intrinsic aggregation rate Langmuir : the ACS journal of surfaces and colloids
22069302 2012-01-01 Surface chemical immobilization of parylene C with thermosensitive block copolymer brushes based on N-isopropylacrylamide and N-tert-butylacrylamide: synthesis, characterization, and cell adhesion/detachment Journal of biomedical materials research. Part B, Applied biomaterials
22629123 2012-01-01 The study of release of chlorhexidine from preparations with modified thermosensitive poly-N-isopropylacrylamide microspheres TheScientificWorldJournal
20387873 2010-05-18 Dynamic viscoelasticity and concentration dependence of micelle-gel transition of styrene and N-tert-butylacrylamide diblock copolymer solutions Langmuir : the ACS journal of surfaces and colloids
20179998 2010-05-01 Polarity assessment of thermoresponsive poly(NIPAM-co-NtBA) copolymer films using fluorescence methods Journal of fluorescence
19994868 2010-04-20 Hydrophobic-electrostatic balance driving the LCST offset aggregation-redissolution behavior of N-alkylacrylamide-based ionic terpolymers Langmuir : the ACS journal of surfaces and colloids
19481217 2009-12-11 Development of a temperature-responsive agarose-based ion-exchange chromatographic resin Journal of chromatography. A
19580282 2009-07-29 Importance of C-N bond rotation in N-acyl oxazolidinones in their SmI2-promoted coupling to acrylamides Journal of the American Chemical Society
The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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