N,N-Dimethylacrylamide
Product Information
Molecular Formula
C5H9NO
Molecular Weight
99.13
Description
N,N-Dimethylacrylamide is an imperative monomeric compound extensively utilized in the fabrication of polyacrylamide-derived hydrogels and biocompatible substrates. This multifaceted entity demonstrates remarkable potential within diverse domains such as pharmaceutics, as it effectively enables drug administration systems, tissue construction processes, and bioactive molecule encapsulation. Remarkably, N,N-Dimethylacrylamide also exhibits profound significance in the realm of biomedical engineering, notably through its pivotal role in surficial coatings and adhesive formulations.
Synonyms
Acrylamide, N,N-dimethyl-; Acylamide, N,N-dimethyl; Dimethylamid kyseliny akrylove; dimethylamidkyselinyakrylove; n,n-dimethyl-2-propenamid; n,n-dimethyl-acrylamid
IUPAC Name
N,N-dimethylprop-2-enamide
SMILES
CN(C)C(=O)C=C
InChI
InChI=1S/C5H9NO/c1-4-5(7)6(2)3/h4H,1H2,2-3H3
InChI Key
YLGYACDQVQQZSW-UHFFFAOYSA-N
Boiling Point
80-81°C
Flash Point
77 °C
Purity
95%
Density
0.962
Appearance
Colorless liquid
Application
Used to make polymers and thermoplastics.
Safety Information
Hazards
H302:
Harmful if swallowed.
H311:
Toxic in contact with skin.
H315:
Causes skin irritation.
H319:
Causes serious eye irritation.
Harmful if swallowed.
H311:
Toxic in contact with skin.
H315:
Causes skin irritation.
H319:
Causes serious eye irritation.
Precautionary Statement
P264:
Wash thoroughly after handling.
P280:
Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352+P312:
IF ON SKIN:
Wash with plenty of soap and water.
Call a POISON CENTER or doctor/physician if you feel unwell.
P337+P313:
If eye irritation persists:
Get medical advice/attention.
P361+P364:
Take off immediately all contaminated clothing. [As modified by IV ATP].
And wash it before reuse. [Added by IV ATP].
P501:
Dispose of contents/container in accordance with local/regional/national/international regulations.
Wash thoroughly after handling.
P280:
Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352+P312:
IF ON SKIN:
Wash with plenty of soap and water.
Call a POISON CENTER or doctor/physician if you feel unwell.
P337+P313:
If eye irritation persists:
Get medical advice/attention.
P361+P364:
Take off immediately all contaminated clothing. [As modified by IV ATP].
And wash it before reuse. [Added by IV ATP].
P501:
Dispose of contents/container in accordance with local/regional/national/international regulations.
Computed Properties
XLogP3
0.3
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
1
Rotatable Bond Count
1
Exact Mass
99.068413911 g/mol
Monoisotopic Mass
99.068413911 g/mol
Topological Polar Surface Area
20.3Ų
Heavy Atom Count
7
Formal Charge
0
Complexity
86.1
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| CN-114163161-A | Modifier for concrete and preparation process thereof | 2022-01-21 |
| CN-114085391-A | High-sensitivity flexible pressure sensing material in pure water and application thereof | 2022-01-20 |
| CN-114163581-A | Concrete tackifier and preparation method thereof | 2021-12-28 |
| CN-114106243-A | Preparation method of low-viscosity low-monomer-residue dry strength agent | 2021-12-27 |
| CN-114133486-A | Bionic anisotropic hybrid cross-linked hydrogel and preparation method and application thereof | 2021-12-21 |
| CN-114181682-A | High-temperature-resistant salt-resistant cross-linked polymer filtrate reducer and preparation method and application thereof | 2021-12-21 |
| JP-2022040149-A | Adhesive composition and laminated film using it | 2021-12-21 |
| CN-114015388-A | Hydroxyl-containing viscose reducing agent composition and preparation method and application thereof | 2021-12-20 |
| CN-114105593-A | Light sound-insulation prefabricated slab and manufacturing method thereof | 2021-12-20 |
| CN-114133879-A | Antistatic UV (ultraviolet) viscosity-reducing adhesive and preparation method thereof | 2021-12-20 |
Literatures
| PMID | Publication Date | Title | Journal |
|---|---|---|---|
| 21750182 | 2012-11-01 | Hyaluronic acid as an internal wetting agent in model DMAA/TRIS contact lenses | Journal of biomaterials applications |
| 23103536 | 2012-10-26 | Preparation, characterization and efficacy evaluation of synthetic biocompatible polymers linking natural antioxidants | Molecules (Basel, Switzerland) |
| 22823739 | 2012-08-21 | Structure of surfaces and interfaces of poly(N,N-dimethylacrylamide) hydrogels | Langmuir : the ACS journal of surfaces and colloids |
| 22711229 | 2012-07-28 | Amphiphilic heteroarm star polymer synthesized by RAFT dispersion polymerization in water/ethanol solution | Chemical communications (Cambridge, England) |
| 22821484 | 2012-07-01 | Surfactant-induced electroosmotic flow in microfluidic capillaries | Electrophoresis |
| 22966547 | 2012-07-01 | Ophthalmic application of poly(HEMA)s containing nanoparticles and dimethylacrylamide | Journal of nanoscience and nanotechnology |
| 22461082 | 2012-05-21 | Highly hydrophilic copolymers of N,N-dimethylacrylamide, acrylamido-2-methylpropanesulfonic acid, and ethylenedimethacrylate: nanoscale morphology in the swollen state and use as exotemplates for synthesis of nanostructured ferric oxide | Chemistry (Weinheim an der Bergstrasse, Germany) |
| 22648809 | 2012-05-01 | Divergent dispersion behavior of ssDNA fragments during microchip electrophoresis in pDMA and LPA entangled polymer networks | Electrophoresis |
| 22589100 | 2012-04-01 | Microchip electrophoresis of DNA following preconcentration at photopatterned gel membranes | Electrophoresis |
| 22023749 | 2012-02-01 | A substrate-independent method for surface grafting polymer layers by atom transfer radical polymerization: reduction of protein adsorption | Acta biomaterialia |
