4-Benzyloxybenzyl alcohol resin

Product Information

Molecular Formula
C15H16O2
Molecular Weight
228.29
Description
4-Benzyloxybenzyl alcohol resin is a versatile compound widely utilized in solid-phase synthesis, particularly in peptide and oligonucleotide production. Its structure features a benzyl ether linkage, which provides stability and facilitates the release of synthesized molecules upon cleavage. The resin serves as an effective support matrix, allowing for the efficient attachment and elongation of molecular chains. Its robust chemical properties make it a reliable choice for researchers seeking precision in complex synthetic processes.
Synonyms
Wang resin; Alko Resin; p-Alkoxybenzyl alcohol resin; p-Methoxybenzyl alcohol resin
IUPAC Name
[4-[(4-methylphenyl)methoxy]phenyl]methanol
Canonical SMILES
CC1=CC=C(C=C1)COC2=CC=C(C=C2)CO
InChI
InChI=1S/C15H16O2/c1-12-2-4-14(5-3-12)11-17-15-8-6-13(10-16)7-9-15/h2-9,16H,10-11H2,1H3
InChI Key
NERFNHBZJXXFGY-UHFFFAOYSA-N
Purity
100-200M
Density
1.117 g/cm3
Solubility
None
Appearance
Pale yellow beads
Storage
Store at 2-8°C

Safety Information

Hazards
H302
Precautionary Statement
P264-P270-P301+P312-P330
GHS Pictogram
GHS07
Signal Word
Warning

Computed Properties

XLogP3
2.9
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
2
Rotatable Bond Count
4
Exact Mass
228.115029749
Monoisotopic Mass
228.115029749
Topological Polar Surface Area
29.5
Heavy Atom Count
17
Formal Charge
0
Complexity
201
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes

Patents

Publication Number Title Priority Date
EP-3608317-A1 Compounds & methods for the enhanced degradation of targeted proteins & other polypeptides by an e3 ubiquitin ligase 2012-01-12
US-2014356322-A1 Compounds & Methods for the Enhanced Degradation of Targeted Proteins & Other Polypeptides by an E3 Ubiquitin Ligase 2012-01-12
US-2019127359-A1 Compounds & Methods for the Enhanced Degradation of Targeted Proteins & Other Polypeptides by an E3 Ubiquitin Ligase 2012-01-12
WO-2013106643-A2 Compounds & methods for the enhanced degradation of targeted proteins & other polypeptides by an e3 ubiquitin ligase 2012-01-12
WO-2013106646-A2 Compounds and methods for the inhibition of vcb e3 ubiquitin ligase 2012-01-12
US-2014296144-A1 Process for the preparation of octreotide acetate 2011-09-30
US-2014241985-A1 Chelated PSMA Inhibitors 2011-06-15
US-2017072075-A1 Chelated PSMA Inhibitors 2011-06-15
US-9446157-B2 Chelated PSMA inhibitors 2011-06-15
US-2014113868-A1 Peptide analogues with an excellent moisturizing effect and use thereof 2011-05-23

Literatures

PMID Publication Date Title Journal
19649769 2010-04-01 Inhibitors of N(alpha)-acetyl-L-ornithine deacetylase: synthesis, characterization and analysis of their inhibitory potency Amino acids
19924038 2009-09-30 Solid-phase synthesis of optically active substituted 2 aminofuranones using an activated carbonate linker Molecules (Basel, Switzerland)
17867699 2007-10-11 A nonacid degradable linker for solid-phase synthesis Organic letters
The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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