Amino-PEG3-propionic acid

Product Information

Molecular Formula:
C9H19NO5
Molecular Weight:
221.25
Description
Amino-PEG3-C2-acid is a cleavable PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
Synonyms
3-(2-(2-(2-Aminoethoxy)ethoxy)ethoxy)propanoic acid; H2N-PEG3-CH2CH2COOH
IUPAC Name
3-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]propanoic acid
Canonical SMILES
C(COCCOCCOCCN)C(=O)O
InChI
InChI=1S/C9H19NO5/c10-2-4-14-6-8-15-7-5-13-3-1-9(11)12/h1-8,10H2,(H,11,12)
InChI Key
XUQZKSCQPMNDEY-UHFFFAOYSA-N
Boiling Point
372.1±32.0 °C at 760 mmHg
Purity
≥ 97.0 %
Density
1.1±0.1 g/cm3
Solubility
10 mm in DMSO
Appearance
White powder
Storage
Store at -20 °C, keep in dry and avoid sunlight.
LogP
0.16990

Safety Information

Hazards
H302-H315-H319-H335
Precautionary Statement
P261-P305+P351+P338
GHS Pictogram
GHS07
Signal Word
Warning

Computed Properties

XLogP3
-3.9
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
6
Rotatable Bond Count
11
Exact Mass
221.12632271
Monoisotopic Mass
221.12632271
Topological Polar Surface Area
91
Heavy Atom Count
15
Formal Charge
0
Complexity
153
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes

Patents

Publication Number Title Priority Date
WO-2022198319-A1 Use of a cold fgfr3-targeting molecule and a fgfr3 targeting radioimmunoconjugate for treating cancer 2021-03-23
WO-2022192597-A2 Affinity agents 2021-03-10
WO-2022180145-A2 Inhibitors of il-11 or il-11ra for use in the treatment of abnormal uterine bleeding 2021-02-26
WO-2022180172-A1 Inhibitors of il-11 or il-11ra for use in the treatment of abnormal uterine bleeding 2021-02-26
WO-2022155385-A1 Methods and compositions for visualizing a ureter in a surgical procedure 2021-01-14
EP-4011904-A1 Masp inhibitory compounds and uses thereof 2020-12-14
WO-2022120177-A1 Nerve targeting peptides and methods of use 2020-12-04
WO-2022112400-A1 Poly-diacetylene sensors and methods for characterizing samples 2020-11-26
WO-2022096394-A1 Masp inhibitory compounds and uses thereof 2020-11-04
WO-2022052823-A1 Small-molecule conjugate and use thereof 2020-09-11
The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Related Products

Online Inquiry
  • Verification code
USA
  • International:
  • US & Canada (Toll free):
  • Email:
  • Fax:
UK
  • Email:
Copyright © 2025 BOC Sciences. All rights reserved.
Top
0
Inquiry Basket

We use cookies to understand how you use our site and to improve the overall user experience. This includes personalizing content and advertising. Read our Privacy Policy

Accept Cookies
x