α-Bromoisobutyryl bromide

Inquiry

Molecular Formula:

C4H6Br2O

Molecular Weight:

229.90

CAS Number:

20769-85-1

Catalog Number:

20769-85-1

Product Information

Molecular Formula:

C4H6Br2O

Molecular Weight:

229.90

Description

α-Bromoisobutyryl bromide has been used: as atom transfer radical polymerization (ATRP) initiator for functionalization of hydroxyl groups present on the surface of graphene oxide; to form an N-protected halodienamide which provided four- and five-membered lactams in the presence of copper (I) and a tertiary amine; in preparation of polycaprolactone macroinitiator via reaction with oligomeric caprolactone diol and mesoporous silica nanoparticles with ATRP initiator anchored on the exterior surface.

Synonyms

2-bromo-2-methylpropanoyl bromide

IUPAC Name

2-bromo-2-methylpropanoyl bromide

Canonical SMILES

CC(C)(C(=O)Br)Br

InChI

InChI=1S/C4H6Br2O/c1-4(2,6)3(5)7/h1-2H3

InChI Key

YOCIJWAHRAJQFT-UHFFFAOYSA-N

Boiling Point

162-164 °C (lit.)

Flash Point

235.4 °F

Purity

98 %

Density

1.86 g/cm³

Appearance

Powder

Application

Used to make fine and large scale chemicals.

Storage

2-8 °C

Refractive Index

n20/D 1.507 (lit.)

Stability

Stable, but may react with moisture. Incompatible with water, strong oxidizing agents, strong bases.

LogP

2.08140

Vapor Pressure

2.11mmHg at 25°C

Safety Information

Hazards

H314 H290

Precautionary Statement

P260, P261, P264, P270, P272, P280, P301+P312, P301+P330+P331, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P310, P321, P330, P333+P313, P363, P405, and P501

Signal Word

Danger

Computed Properties

XLogP3

2.2

Hydrogen Bond Donor Count

Hydrogen Bond Acceptor Count

Rotatable Bond Count

Exact Mass

229.87649 g/mol

Monoisotopic Mass

227.87854 g/mol

Topological Polar Surface Area

17.1Å²

Heavy Atom Count

Formal Charge

Complexity

87.7

Isotope Atom Count

Defined Atom Stereocenter Count

Undefined Atom Stereocenter Count

Defined Bond Stereocenter Count

Undefined Bond Stereocenter Count

Covalently-Bonded Unit Count

Compound Is Canonicalized

Yes

Patents

Publication Number	Title	Priority Date
CN-114134707-A	Preparation process method of antibacterial yarn	2021-12-29
CN-114149600-A	Preparation method and application of temperature-responsive hydrogel	2021-12-27
CN-114149588-A	Star initiator and preparation method thereof	2021-12-23
CN-114059560-A	Inclined pile construction method	2021-12-22
CN-113956468-A	Synthetic method of polypeptide/polyolefin hybrid copolymer	2021-12-14
CN-113861264-A	Avidin modification method, application method and kit thereof	2021-12-03
CN-114085484-A	High-strength high-toughness composite material, preparation method and application	2021-11-26
CN-114158551-A	Nano pesticide preparation capable of rapidly responding to weak alkaline environment, preparation method and application thereof	2021-11-22
CN-113930039-A	Bamboo-plastic composite board material for container bottom board	2021-11-18
CN-114044853-A	Biomass-based EC-g-PSSA graft copolymer and preparation method and application thereof	2021-11-15

Literatures

PMID	Publication Date	Title	Journal
22575755	2012-08-20	PHEA-graft-polybutylmethacrylate copolymer microparticles for delivery of hydrophobic drugs	International journal of pharmaceutics
22709433	2012-07-18	Star-like oligo-arginyl-maltotriosyl derivatives as novel cell-penetrating enhancers for the intracellular delivery of colloidal therapeutic systems	Bioconjugate chemistry
22524250	2012-05-10	Imidazolopiperazines: lead optimization of the second-generation antimalarial agents	Journal of medicinal chemistry
22701519	2012-01-01	Thermoresponsive micropatterned substrates for single cell studies	PloS one
21882878	2011-10-18	Bifunctional nanoparticles with fluorescence and magnetism via surface-initiated AGET ATRP mediated by an iron catalyst	Langmuir : the ACS journal of surfaces and colloids
22064690	2011-10-01	2-Bromo-N-(4-chloro-phen-yl)-2-methyl-propanamide	Acta crystallographica. Section E, Structure reports online
21663960	2011-09-01	Amphiphilic multiarm star block copolymer-based multifunctional unimolecular micelles for cancer targeted drug delivery and MR imaging	Biomaterials
21565356	2011-08-15	Chemical and nanomechanical analysis of rice husk modified by ATRP-grafted oligomer	Journal of colloid and interface science
21563843	2011-06-07	Biomimetic anchors for antifouling and antibacterial polymer brushes on stainless steel	Langmuir : the ACS journal of surfaces and colloids
21277397	2011-05-01	Uniform polymer-protein conjugate by aqueous AGET ATRP using protein as a macroinitiator	Acta biomaterialia

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