2-(4-Morpholino)ethyl 2-bromoisobutyrate
Product Information
Molecular Formula
C10H18BrNO3
Molecular Weight
280.16
Description
This bromoisobutyrate is commonly used as an ATRP initiator. The morpholino functionality can be used to bind to RNA or other therapeutics.
Synonyms
2-Bromo-2-methylpropanoic acid 2-(4-morpholinyl)ethyl ester,2-Morpholinoethyl 2-bromo-2-methylpropanoate,ATRP initiator
IUPAC Name
2-morpholin-4-ylethyl 2-bromo-2-methylpropanoate
SMILES
CC(C)(C(=O)OCCN1CCOCC1)Br
InChI
InChI=1S/C10H18BrNO3/c1-10(2,11)9(13)15-8-5-12-3-6-14-7-4-12/h3-8H2,1-2H3
InChI Key
XEXMMWOKORAPHR-UHFFFAOYSA-N
Boiling Point
65-67 °C/11 mmHg(lit.)
Flash Point
>230 °F
Purity
95% (excluding up to 10% residual Toluene)
Density
1.258 at 25 °C
Appearance
liquid
Storage
2-8°C
Refractive Index
n/D 1.486
Computed Properties
XLogP3
1.2
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
4
Rotatable Bond Count
5
Exact Mass
279.04701 g/mol
Monoisotopic Mass
279.04701 g/mol
Topological Polar Surface Area
38.8Ų
Heavy Atom Count
15
Formal Charge
0
Complexity
215
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| WO-2018209293-A2 | Nanoscale multiple emulsions and nanoparticles | 2017-05-11 |
| US-2020385503-A1 | Nanoscale multiple emulsions and nanoparticles | 2017-05-11 |
| WO-2018136666-A1 | Multimodal chromatographic media for protein separation | 2017-01-20 |
| EP-3570974-B1 | Multimodal chromatographic media for protein separation | 2017-01-20 |
| EP-3458859-A1 | Diagnostic methods for the detection and quantification of blood-related diseases | 2016-05-19 |
| US-2019154685-A1 | Diagnostic methods for the detection and quantification of blood-related diseases | 2016-05-19 |
| WO-2017198850-A1 | Diagnostic methods for the detection and quantification of blood-related diseases | 2016-05-19 |
| US-10983122-B2 | Diagnostic methods for the detection and quantification of blood-related diseases | 2016-05-19 |
| WO-2016005689-A1 | Use of an aminated homopolymer for encapsulating ingredients, method of synthesizing an aema homopolymer and method of encapsulating ingredients | 2014-07-10 |
| EP-2282720-A2 | Intracellular antibody delivery | 2008-05-15 |
Literatures
| PMID | Publication Date | Title | Journal |
|---|---|---|---|
| 20454666 | 2010-05-03 | Enhanced fluorescence imaging of live cells by effective cytosolic delivery of probes | PloS one |
