1,4,8,11-TETRAMETHYL-1,4,8,11-TETRAAZACYCLOTETRADECANE
Product Information
Molecular Formula
C14H32N4
Molecular Weight
256.43
Description
N,N,N',N'-Tetrakis(2-pyridylmethyl)ethylenediamine has been used:• in the treatment of human embryonic kidney (HEK293T) cells for assessing its effect on the Jembrana disease virus (JDV) viral infectivity factor (Vif) functionality• in P19 embryonic carcinoma cells for chelation of zinc ions released during apoptosis • to evaluate its effect on lentiviral Vpx infection on human monocytic THP-1 cells
Synonyms
1,4,8,11-TETRAMETHYL-1,4,8,11-TETRAAZACYCLOTETRADECANE; Tetramethylcyclam; 1,4,8,11-Tetramethyl-1,4,8,11-tetraazacyclotetradecane,98%; 1,5,8,12-Tetramethyl-1,5,8,12-tetraazacyclotetradecane
IUPAC Name
1,4,8,11-tetramethyl-1,4,8,11-tetrazacyclotetradecane
SMILES
CN1CCCN(CCN(CCCN(CC1)C)C)C
InChI
InChI=1S/C14H32N4/c1-15-7-5-8-17(3)13-14-18(4)10-6-9-16(2)12-11-15/h5-14H2,1-4H3
InChI Key
HRFJEOWVAGSJNW-UHFFFAOYSA-N
Boiling Point
198 °C(lit.)
Melting Point
38-42 °C (lit.)
Flash Point
230.0 °F - closed cup
Purity
98%
Density
0.876 g/cm3
Appearance
white to slightly yellow low melting crystalline
Refractive Index
n20/D 1.442 (lit.)
Safety Information
Hazards
H315 H319
Precautionary Statement
P264 P280 P302 + P352 P337 + P313 P305 + P351 + P338 P362+P364 P332 + P313
Computed Properties
XLogP3
0.4
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
4
Rotatable Bond Count
0
Exact Mass
256.26269704 g/mol
Monoisotopic Mass
256.26269704 g/mol
Topological Polar Surface Area
13Ų
Heavy Atom Count
18
Formal Charge
0
Complexity
168
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| JP-2022039817-A | Photoresponsive polymers, photoresponsive adhesives, toners, and image forming methods | 2020-08-28 |
| US-2022066345-A1 | Photoresponsive polymer, photoresponsive adhesive, toner, and image forming method | 2020-08-28 |
| JP-2022031010-A | Photoresponsive polymer | 2020-08-07 |
| US-2022043366-A1 | Photoresponsive polymer | 2020-08-07 |
| CN-113943440-A | Method for producing porous microstructures | 2020-07-17 |
| US-11236184-B1 | Method for producing porous microstructure | 2020-07-17 |
| US-2022017662-A1 | Method for producing porous microstructure | 2020-07-17 |
| WO-2022014492-A1 | Polymerization initiator, kit for preparing curable composition, curable composition, cured product, and dental material | 2020-07-15 |
| CN-113552782-A | Light-responsive material, adhesive, photoswitch material, toner, and image forming method | 2020-04-24 |
| JP-2021175783-A | Photoresponsive materials, adhesives, optical switching materials, toners and image forming methods | 2020-04-24 |
Literatures
| PMID | Publication Date | Title | Journal |
|---|---|---|---|
| 22837063 | 2012-09-10 | Intramolecular gas-phase reactions of synthetic nonheme oxoiron(IV) ions: proximity and spin-state reactivity rules | Chemistry (Weinheim an der Bergstrasse, Germany) |
| 22708532 | 2012-07-18 | [Fe(IV)═O(TBC)(CH3CN)]2+: comparative reactivity of iron(IV)-oxo species with constrained equatorial cyclam ligation | Journal of the American Chemical Society |
| 21678930 | 2011-07-18 | Theoretical study of the mechanism of oxoiron(IV) formation from H2O2 and a nonheme iron(II) complex: O-O cleavage involving proton-coupled electron transfer | Inorganic chemistry |
| 21526756 | 2011-06-06 | Reaction of an oxoiron(IV) complex with nitrogen monoxide: oxygen atom or oxide(•1-) ion transfer? | Inorganic chemistry |
| 20729896 | 2010-09-01 | Crystal structure of a metal ion-bound oxoiron(IV) complex and implications for biological electron transfer | Nature chemistry |
| 20199095 | 2010-04-05 | Spectroscopic and computational studies of a trans-mu-1,2-disulfido-bridged dinickel species, [{(tmc)Ni}(2)(S(2))](OTf)(2): comparison of end-on disulfido and peroxo bonding in (Ni(II))(2) and (Cu(II))(2) species | Inorganic chemistry |
| 19916032 | 2010-03-01 | Steric hindrance effect of the equatorial ligand on Fe(IV)O and Ru(IV)O complexes: a density functional study | Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry |
| 20121136 | 2010-02-24 | Near-stoichiometric conversion of H(2)O(2) to Fe(IV)=O at a nonheme iron(II) center. Insights into the O-O bond cleavage step | Journal of the American Chemical Society |
| 20104361 | 2010-02-07 | Dissolved N(2) sensing by pH-dependent Ru complexes | Dalton transactions (Cambridge, England : 2003) |
| 19937616 | 2010-01-04 | Contrasting effects of axial ligands on electron-transfer versus proton-coupled electron-transfer reactions of nonheme oxoiron(IV) complexes | Chemistry (Weinheim an der Bergstrasse, Germany) |
