2-Bromoisobutanoic acid N-hydroxysuccinimide ester
Product Information
Molecular Formula
C8H10BrNO4
Molecular Weight
264.07
Description
Atom transfer radical polymerization (ATRP) initiator with an NHS ester moiety for conjugation chemistry, useful for biological ligations.
Synonyms
1-(2-Bromo-2-methyl-1-oxopropoxy)-2,5-pyrrolidinedione,NHS ATRP initiator,NHS protected Bromoisobutyrate,NHS-BiB
IUPAC Name
(2,5-dioxopyrrolidin-1-yl) 2-bromo-2-methylpropanoate
SMILES
CC(C)(C(=O)ON1C(=O)CCC1=O)Br
InChI
InChI=1S/C8H10BrNO4/c1-8(2,9)7(13)14-10-5(11)3-4-6(10)12/h3-4H2,1-2H3
InChI Key
QBJWGGWPQPRVKW-UHFFFAOYSA-N
Melting Point
135-140 °C
Flash Point
>230 °F
Purity
98% (GC)
Appearance
solid
Storage
2-8°C
Refractive Index
n20/D 1.529
Computed Properties
XLogP3
0.6
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
4
Rotatable Bond Count
3
Exact Mass
262.97932 g/mol
Monoisotopic Mass
262.97932 g/mol
Topological Polar Surface Area
63.7Ų
Heavy Atom Count
14
Formal Charge
0
Complexity
284
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| EP-3788343-A1 | Stimuli-responsive peg-like polymer-based drug delivery platform | 2018-04-30 |
| US-2021128734-A1 | Stimuli-responsive peg-like polymer-based drug delivery platform | 2018-04-30 |
| US-2020385503-A1 | Nanoscale multiple emulsions and nanoparticles | 2017-05-11 |
| US-10211400-B2 | Photopatterned growth of electronically active brush polymers for light emitting diode displays | 2017-03-31 |
| US-10228619-B2 | Photopatterned growth of electronically active brush polymers for light emitting diode displays | 2017-03-31 |
| US-2018284608-A1 | Photopatterned growth of electronically active brush polymers for light emitting diode displays | 2017-03-31 |
| US-2018287065-A1 | Photopatterned growth of electronically active brush polymers for light emitting diode displays | 2017-03-31 |
| WO-2018141832-A1 | Transparent scratch-resistant layer having anti-fouling properties and method for producing same | 2017-02-01 |
| US-2020062871-A1 | Reactions enabled by thermoresponsive and photoresponsive gels | 2017-01-30 |
| WO-2018140977-A1 | Reactions enabled by thermoresponsive and photoresponsive gels | 2017-01-30 |
