N,N'-p-phenylenedimaleimide

Inquiry

Molecular Formula:

C14H8N2O4

Molecular Weight:

268.2244

CAS Number:

3278-31-7

Catalog Number:

3278-31-7

Product Information

Molecular Formula:

C14H8N2O4

Molecular Weight:

268.2244

Description

N,N'-p-phenylenedimaleimide is an indispensable compound in the pharmaceutical sector and is extensively employed as a cross-linking reagent. Its multifaceted application encompasses peptide-based drug synthesis and exploration of protein-protein interactions. Moreover, its utility extends to drug delivery systems, nanotechnology, and molecular imaging techniques targeting a wide range of ailments like cancer, cardiovascular disorders, and neurodegenerative conditions.

Synonyms

N,N'-P-PHENYLENEDIMALEIMIDE; N,N'-1,4-PHENYLENEBISMALEIMIDE; N,N'-1,4-PHENYLENEDIMALEIMIDE; N,N'-1,4-BISMALEIMIDOBENZENE; n,n'-4-phenylenedimaleimide; 1,4-DIMALEIMIDOBENZENE; 1,4-PHENYLENE-BIS-MALEIMIDE; 1,4-PDM

IUPAC Name

1-[4-(2,5-dioxopyrrol-1-yl)phenyl]pyrrole-2,5-dione

Canonical SMILES

C1=CC(=CC=C1N2C(=O)C=CC2=O)N3C(=O)C=CC3=O

InChI

InChI=1S/C14H8N2O4/c17-11-5-6-12(18)15(11)9-1-2-10(4-3-9)16-13(19)7-8-14(16)20/h1-8H

InChI Key

AQGZJQNZNONGKY-UHFFFAOYSA-N

Boiling Point

411.39°C (rough estimate)

Melting Point

>300 °C(lit.)

Purity

>98.0%(LC)(T)

Density

1.567g/cm3

Appearance

Off-White Solid

Application

A short, sulfhydryl reactive hmombifunctional crosslinking reagent for protein crosslinking.

Refractive Index

1.5910 (estimate)

Safety Information

Hazards

H302:
Harmful if swallowed.

Precautionary Statement

P264:
Wash thoroughly after handling.
P270:
Do not eat, drink or smoke when using this product.
P301+P312+P330:
IF SWALLOWED:
Call a POISON CENTER or doctor/physician if you feel unwell.
Rinse mouth.
P501:
Dispose of contents/container in accordance with local/regional/national/international regulations.

Computed Properties

XLogP3

0.2

Hydrogen Bond Donor Count

Hydrogen Bond Acceptor Count

Rotatable Bond Count

Exact Mass

268.04840674 g/mol

Monoisotopic Mass

268.04840674 g/mol

Topological Polar Surface Area

74.8Å²

Heavy Atom Count

Formal Charge

Complexity

470

Isotope Atom Count

Defined Atom Stereocenter Count

Undefined Atom Stereocenter Count

Defined Bond Stereocenter Count

Undefined Bond Stereocenter Count

Covalently-Bonded Unit Count

Compound Is Canonicalized

Yes

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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N,N'-p-phenylenedimaleimide

Product Information

Safety Information

Computed Properties

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