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1,2-Bis(maleimido)ethane

1,2-Bis(maleimido)ethane

Name: 1,2-Bis(maleimido)ethane
Brand: BOC Sciences
Rating: 5 (1 reviews)

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Molecular Formula:

C10H8N2O4

Molecular Weight:

220.108

CAS Number:

5132-30-9

Catalog Number:

BPM-398970

Product Information

Molecular Formula

C10H8N2O4

Molecular Weight

220.108

Description

1,2-Bis(maleimido)ethane is a versatile cross-linking agent widely used in biochemical applications for its ability to form stable covalent bonds. This compound is particularly effective in linking sulfhydryl groups on proteins, facilitating the study of protein-protein interactions and complex formation. Its bifunctional nature allows for the creation of polymer networks and other macromolecular assemblies, enhancing research capabilities in structural biology. As a reagent, 1,2-Bis(maleimido)ethane offers a reliable solution for advancing experimental methodologies in various laboratory settings.

Synonyms

Ethylenebismaleimide; N,N'-Ethylenedimaleimide; N,N'-Ethylenebismaleimide; Ethylenebiemaleimide; EBM; 1,2-Bis-maleimidoethane; 1,1'-(1,2-Ethanediyl)bis-1H-pyrrole-2,5-dione; NSC 41127; ACMC-1AYAG; BMOE (bismaleimidoethane)

IUPAC Name

1-[2-(2,5-dioxopyrrol-1-yl)ethyl]pyrrole-2,5-dione

Canonical SMILES

C1=CC(=O)N(C1=O)CCN2C(=O)C=CC2=O

InChI

InChI=1S/C10H8N2O4/c13-7-1-2-8(14)11(7)5-6-12-9(15)3-4-10(12)16/h1-4H,5-6H2

InChI Key

PUKLCKVOVCZYKF-UHFFFAOYSA-N

Boiling Point

428.3±28.0 °C (Predicted)

Melting Point

193-194 °C

Purity

95%

Density

1.510±0.06 g/cm3 (Predicted)

Solubility

Soluble in Chloroform

Appearance

Off White Solid

Storage

2-8 °C

Safety Information

Hazards

H315:
Causes skin irritation.
H319:
Causes serious eye irritation.

Precautionary Statement

P264:
Wash thoroughly after handling.
P280:
Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352:
IF ON SKIN:
Wash with plenty of soap and water.
P332+P313:
If skin irritation occurs:
Get medical advice/attention.
P337+P313:
If eye irritation persists:
Get medical advice/attention.
P362+P364:
Take off contaminated clothing. [As modified by IV ATP].
And wash it before reuse. [Added by IV ATP].

Computed Properties

XLogP3

-1.3

Hydrogen Bond Donor Count

Hydrogen Bond Acceptor Count

Rotatable Bond Count

Exact Mass

220.04840674 g/mol

Monoisotopic Mass

220.04840674 g/mol

Topological Polar Surface Area

74.8Å²

Heavy Atom Count

Formal Charge

Complexity

372

Isotope Atom Count

Defined Atom Stereocenter Count

Undefined Atom Stereocenter Count

Defined Bond Stereocenter Count

Undefined Bond Stereocenter Count

Covalently-Bonded Unit Count

Compound Is Canonicalized

Yes

Patents

Publication Number	Title	Priority Date
JP-2022028036-A	Dry films, cured products, and electronic components	2021-12-21
CN-113980270-A	Bismaleimide composite material based on disulfide bond and Diels-Alder reaction and preparation method thereof	2021-12-01
JP-2022031295-A	Manufacturing method of composite molded product	2021-11-26
CN-113980271-A	Soybean oil-based self-repairing shape memory polymer and preparation method thereof	2021-10-20
CN-113717182-A	Naphthoquinone polycyclic derivative, preparation method and application thereof	2021-09-24
CN-113337098-A	Thermosetting resin composition and application thereof	2021-06-28
CN-113248900-A	Dynamic bond crosslinking high-filling heat-conducting composite material and preparation method and application thereof	2021-05-20
CN-112898919-A	Novel low-VOC (volatile organic compound) heat vulcanization adhesive and use method thereof	2021-02-05
CN-112812711-A	High-reactivity metal-rubber heat-vulcanization adhesive and using method thereof	2021-01-25
JP-2021080457-A	Thermosetting resin compositions, prepregs, laminates, printed wiring boards and semiconductor packages	2021-01-13

Literatures

PMID	Publication Date	Title	Journal
21707059	2011-07-27	Bioluminescence is produced from a trapped firefly luciferase conformation predicted by the domain alternation mechanism	Journal of the American Chemical Society

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