Pentadecanolide

Product Information

Molecular Formula:
C15H28O2
Molecular Weight:
240.38
Description
Pentadecanolide (CAS# 106-02-5) is a monomer used to make PGA-co-pentadecalactone polymers to be used in the development of directly compressed prolonged release tablets of slightly soluble drugs such as ketoprofen.
Synonyms
oxacyclohexadecan-2-one
IUPAC Name
oxacyclohexadecan-2-one
Canonical SMILES
C1CCCCCCCOC(=O)CCCCCC1
InChI
InChI=1S/C15H28O2/c16-15-13-11-9-7-5-3-1-2-4-6-8-10-12-14-17-15/h1-14H2
InChI Key
FKUPPRZPSYCDRS-UHFFFAOYSA-N
Boiling Point
137 °C (2 mmHg)
Melting Point
32-38 °C
Flash Point
>230 °F
Purity
95 %
Density
0.918 g/cm3
Solubility
0.1484 mg/L at 25 °C (est)
Appearance
White fine, sharp crystal
Storage
Sealed in dry, Room Temperature
Refractive Index
1.47
LogP
4.61450

Safety Information

Precautionary Statement
P261, P272, P273, P280, P302+P352, P321, P333+P313, P363, P391, and P501
Signal Word
Warning

Computed Properties

XLogP3
5.8
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
2
Rotatable Bond Count
0
Exact Mass
240.208930132 g/mol
Monoisotopic Mass
240.208930132 g/mol
Topological Polar Surface Area
26.3Ų
Heavy Atom Count
17
Formal Charge
0
Complexity
189
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes

Patents

Publication Number Title Priority Date
JP-2022031761-A How to improve the solubility of poorly water-soluble ingredients 2021-11-22
CN-114010543-A Salvia officinalis sea salt essence and preparation method thereof 2021-11-08
JP-2021193141-A Liquid composition containing lipid peptide 2021-09-27
CN-113388095-A Modified solvent-free polyester resin and primer containing resin 2021-08-05
CN-113600012-A High-flux high-rejection nanofiltration membrane modified by carbonic acid lactone and preparation method thereof 2021-07-22
KR-102342695-B1 Cosmetic composition for skin soothing 2021-07-14
CN-113512300-A High-extrusion-efficiency bamboo-based composite material containing carbon nano tubes and preparation method thereof 2021-07-08
DE-202021103593-U1 Skin-friendly, caring and protective agent for application to the skin 2021-07-05
JP-2022023007-A Polyurethane foam 2021-06-30
CN-113122122-A High-solid-content polyurethane ink resin, preparation method and application thereof 2021-04-02

Literatures

PMID Publication Date Title Journal
21802477 2011-12-01 Fragrance material review on ω-pentadecalactone Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
19619678 2010-01-01 Scaffold for tissue engineering fabricated by non-isothermal supercritical carbon dioxide foaming of a highly crystalline polyester Acta biomaterialia
19807145 2009-11-09 Enzymatic one-pot route to telechelic polypentadecalactone epoxide: synthesis, UV curing, and characterization Biomacromolecules
19632718 2009-10-01 Poly(omega-pentadecalactone-co-butylene-co-succinate) nanoparticles as biodegradable carriers for camptothecin delivery Biomaterials
19966909 2009-01-01 Safety and efficacy of testosterone gel in the treatment of male hypogonadism Clinical interventions in aging
18975906 2008-12-01 Polymers from functional macrolactones as potential biomaterials: enzymatic ring opening polymerization, biodegradation, and biocompatibility Biomacromolecules
18939863 2008-11-01 Lipase-catalyzed synthesis of aliphatic polyesters via copolymerization of lactone, dialkyl diester, and diol Biomacromolecules
18618411 2008-06-01 New oxa-bridged macrocycles Chemistry & biodiversity
18198834 2008-02-01 Humicola insolens cutinase-catalyzed lactone ring-opening polymerizations: kinetic and mechanistic studies Biomacromolecules
18198845 2008-02-01 Lipase catalyzed HEMA initiated ring-opening polymerization: in situ formation of mixed polyester methacrylates by transesterification Biomacromolecules
The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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