Poly(maleic acid)

Product Information

Molecular Formula:
C4H4O4
Molecular Weight:
116.07
Description
Maleic acid polymer. 50% solution in water
Synonyms
HPMA; Polymaleic Acid; PolymaleicacidAq; Poly(maleic acid); POLY(MALEIC ACID); MALEIC ACID POLYMER
IUPAC Name
but-2-enedioic acid
Canonical SMILES
C(=CC(=O)O)C(=O)O
InChI
InChI=1S/C4H4O4/c5-3(6)1-2-4(7)8/h1-2H,(H,5,6)(H,7,8)
InChI Key
VZCYOOQTPOCHFL-UHFFFAOYSA-N
Density
1.22-1.25 g/mL
Appearance
Pale yellow to umber transparent liquid
Application
HPMA is usually used together with organic phosphonate at dosage of 1-15ppm for circulating cool water system, oilfield fill water, crude oil dewatering and low-pressure boilers. HPMA has good scale inhibition (98%) and scale stripping properties. When used together with zinc salts, it can effectively inhibit carbon steel corrosion.
Storage
Storage in shady room and dry place.
Concentration
50% soln. in water
Vapor Pressure
10.0 [mmHg]

Safety Information

Hazards
Irritant
Handling
Gloves & fume hood

Computed Properties

XLogP3
-0.3
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
4
Rotatable Bond Count
2
Exact Mass
116.01095860 g/mol
Monoisotopic Mass
116.01095860 g/mol
Topological Polar Surface Area
74.6Ų
Heavy Atom Count
8
Formal Charge
0
Complexity
119
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
1
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes

Patents

Publication Number Title Priority Date
US-2015064111-A1 Novel targeting agents for diagnostic and therapeutic indications 2012-04-03
US-2010160317-A1 2-(2-oxoindoline-3-ylidene)methyl-5-(2-hydroxy-3-morpholin-4-yl-propyl)-6,7-dihydro-1h-pyrrol[3,2-c]pyridine-4(5h)-one compounds and use as protein kinase inhibitors 2007-08-15
EP-1652834-A1 Process for producing salicylic esters 2004-10-29
EP-1652834-B1 Process for producing salicylic esters 2004-10-29
EP-1634571-A1 Transesterification process for producing salicylic esters used in perfumes 2004-09-07
US-2006058547-A1 Process for producing salicylic esters 2004-09-07
US-2011104186-A1 Small molecule immunopotentiators and assays for their detection 2004-06-24
EP-1719794-A1 Novel polymers and uses thereof 2004-01-30
US-2007154431-A1 Novel polymers and uses thereof 2004-01-30
US-7977429-B2 Polymers and uses thereof 2004-01-30

Literatures

PMID Publication Date Title Journal
25171976 2014-11-20 Microenvironmental pH-modified solid dispersions to enhance the dissolution and bioavailability of poorly water-soluble weakly basic GT0918, a developing anti-prostate cancer drug: preparation, characterization and evaluation in vivo International journal of pharmaceutics
23707484 2013-08-01 Fumaric acid attenuates the eotaxin-1 expression in TNF-α-stimulated fibroblasts by suppressing p38 MAPK-dependent NF-κB signaling Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
23066525 2012-12-07 Metabolite profiling of Curcuma species grown in different regions using 1H NMR spectroscopy and multivariate analysis The Analyst
22698672 2012-12-01 Toward understanding the role of mitochondrial complex II in the intraerythrocytic stages of Plasmodium falciparum: gene targeting of the Fp subunit Parasitology international
22982381 2012-12-01 Studies on synthesis, growth, structural, thermal, linear and nonlinear optical properties of organic picolinium maleate single crystals Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
23009796 2012-11-15 Catalytic ozonation of sulphamethoxazole in the presence of carbon materials: catalytic performance and reaction pathways Journal of hazardous materials
23022412 2012-11-15 Comparison of various organic compounds destruction on rare earths doped Ti/Sb-SnO2 electrodes Journal of hazardous materials
22944427 2012-11-06 Preparation of pH- and ionic-strength responsive biodegradable fumaric acid crosslinked carboxymethyl cellulose Carbohydrate polymers
22007931 2012-11-01 Off-label use of fumarate therapy for granulomatous and inflammatory skin diseases other than psoriasis vulgaris: a retrospective study Journal of the European Academy of Dermatology and Venereology : JEADV
22618691 2012-11-01 The role of glutamine synthetase and glutamate dehydrogenase in cerebral ammonia homeostasis Neurochemical research
The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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