1-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]pyrrolidine
Product Information
Molecular Formula
C16H24BNO2
Molecular Weight
273.18
Description
1-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]pyrrolidine, an avant-garde intermediate in the expansive realm of organic synthesis, takes center-stage in boosting drug product bioavailability.
Synonyms
1-[4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PHENYL]PYRROLIDINE; 4-Pyrrolidinophenylboronic acid, pinacol ester; 4-Pyrrolidinophenylboronic acid pinacol ester; 4-(1-Pyrrolidinyl)benzeneboronic acid pinacol ester; 1-[4-(tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]pyrrolidine; 1-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolane-2-yl)phenyl]pyrrolidine; Pyrrolidine, 1-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-; 1-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]pyrrolidine;
IUPAC Name
1-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]pyrrolidine
SMILES
B1(OC(C(O1)(C)C)(C)C)C2=CC=C(C=C2)N3CCCC3
InChI
InChI=1S/C16H24BNO2/c1-15(2)16(3,4)20-17(19-15)13-7-9-14(10-8-13)18-11-5-6-12-18/h7-10H,5-6,11-12H2,1-4H3
InChI Key
DWJNNJSONWFVBT-UHFFFAOYSA-N
Flash Point
Not applicable
Computed Properties
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
3
Rotatable Bond Count
2
Exact Mass
273.1900092 g/mol
Monoisotopic Mass
273.1900092 g/mol
Topological Polar Surface Area
21.7Ų
Heavy Atom Count
20
Formal Charge
0
Complexity
328
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| CN-113549010-A | Preparation and application of compound with AMPK agonistic activity and prodrug thereof | 2020-04-26 |
| US-2020308163-A1 | Compounds and compositions as modulators of tlr signaling | 2019-03-26 |
| CN-114025847-A | Compounds and compositions as modulators of TLR signaling | 2019-03-26 |
| KR-20220004982-A | Compounds and compositions as modulators of TLR signaling | 2019-03-26 |
| CN-108774122-B | Method for synthesizing diaryl ketone compound by carbonylation taking chloroform as carbonyl source without participation of transition metal | 2018-08-10 |
| JP-2019512482-A | Inhibitors of WDR5 protein-protein binding | 2016-03-01 |
| US-2019112290-A1 | Inhibitors of wdr5 protein-protein binding | 2016-03-01 |
| EA-038109-B1 | INHIBITORS OF WDR5 PROTEIN BINDING WITH PROTEINS | 2016-03-01 |
| TW-201629046-A | TANK binding kinase inhibitor compound | 2014-09-26 |
| US-2016214924-A1 | Substituted naphthalene compounds as calcium sensing receptor modulators | 2013-08-28 |
