1-Methyl-2-(2-diphenylphosphinophenyl)-1H-benzoimidazole
Product Information
Molecular Formula
C26H21N2P
Molecular Weight
392.43
Description
Efficient ligand for Suzuki-Miyaura coupling with of aryl mesylates and Buchwald-Hartwig amination with aryl chlorides.
Synonyms
1-methyl-2-(2-diphenylphosphinophenyl)-1h-benzoimidazole; [2-(1-methylbenzimidazol-2-yl)phenyl]-diphenylphosphane; 1-Methyl-2-[2-(diphenylphosphino)phenyl]-1H-benzoimidazole; 1-Methyl-2-(2-diphenylphosphinophenyl)-1H-benzoimidazole, 95%
IUPAC Name
[2-(1-methylbenzimidazol-2-yl)phenyl]-diphenylphosphane
SMILES
CN1C2=CC=CC=C2N=C1C3=CC=CC=C3P(C4=CC=CC=C4)C5=CC=CC=C5
InChI
InChI=1S/C26H21N2P/c1-28-24-18-10-9-17-23(24)27-26(28)22-16-8-11-19-25(22)29(20-12-4-2-5-13-20)21-14-6-3-7-15-21/h2-19H,1H3
InChI Key
BVVIYNVQLLTULW-UHFFFAOYSA-N
Melting Point
166-172 °C
Purity
95%
Storage
20-25°C
Safety Information
Hazards
H315-H319-H335
Precautionary Statement
P261-P305 + P351 + P338
Computed Properties
XLogP3
5.8
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
1
Rotatable Bond Count
4
Exact Mass
392.144235676 g/mol
Monoisotopic Mass
392.144235676 g/mol
Topological Polar Surface Area
17.8Ų
Heavy Atom Count
29
Formal Charge
0
Complexity
495
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| WO-2020152200-A1 | Process for preparation of heteroarylketones | 2019-01-25 |
| WO-2019016115-A1 | PROCESS FOR THE PREPARATION OF SUBSTITUTED ARYLE KETONES | 2017-07-21 |
| EP-2757106-A1 | Substituted benzimidazole phosphine compounds and a method for decarboxylating carbon-carbon bond | 2013-01-21 |
| WO-2014111493-A1 | Substituted benzimidazolyl phosphine compounds and a method for decarboxylating carbon-carbon linking | 2013-01-21 |
| WO-2011152358-A1 | Membrane containing silver complex | 2010-05-31 |
| CA-2662276-A1 | Ligand exchange thermochromic, (letc), systems | 2006-09-01 |
| EP-2082005-A1 | Ligand exchange thermochromic, (letc), systems | 2006-09-01 |
| EP-2082005-B1 | Ligand exchange thermochromic, (letc), systems | 2006-09-01 |
| EP-2082005-B9 | Ligand exchange thermochromic, (letc), systems | 2006-09-01 |
| EP-2434000-A2 | Ligand exchange thermochromic, (LETC), systems | 2006-09-01 |
