1-Methyl-5-(tributylstannyl)imidazole
Product Information
Molecular Formula
C16H32N2Sn
Molecular Weight
371.15
Description
1-Methyl-5-(tributylstannyl)imidazole is a specialized chemical used in the biomedical field. It acts as a reagent in antifungal drug synthesis by providing structural modifications to increase potency against fungal infections.
Synonyms
1-Methyl-5-(tributylstannyl)-1H-imidazole; 1-Methyl-5-(tributylstannyl)imidazole; Tributyl-(3-methylimidazol-4-yl)stannane; 1-Methyl-5-tributylstannanyl-1H-imidazole; 1H-Imidazole, 1-methyl-5-(tributylstannyl)-; 1H-Imidazole,1-methyl-5-(tributylstannyl)-; 5-(tributylstannyl)-1-methylimidazole; 1-methyl-5-tributylstannyl-1H-imidazole; 1-Methyl-5-(tri-n-butylstannyl)imidazole; 5-(tri-n-butylstannyl)-N-methylimidazole; tributyl-(3-methyl-4-imidazolyl)stannane; 1-methyl-5-[tri(n-butyl)stannyl]imidazole; 1-Methyl-5-(tributylstannyl)imidazole, 95%; 5-tri-n-butylstannyl-1-methyl-1H-imidazole
IUPAC Name
tributyl-(3-methylimidazol-4-yl)stannane
SMILES
CCCC[Sn](CCCC)(CCCC)C1=CN=CN1C
InChI
InChI=1S/C4H5N2.3C4H9.Sn/c1-6-3-2-5-4-63*1-3-4-2/h2,4H,1H33*1,3-4H2,2H3
InChI Key
OGYWKJKAIAEDQX-UHFFFAOYSA-N
Boiling Point
160-164 °C/2 mmHg
Flash Point
Not applicable
Purity
95%
Density
1.220 g/mL at 25 °C
Refractive Index
n20/D 1.510
Safety Information
Hazards
H301 - H312 - H315 - H319 - H372 - H410
Precautionary Statement
P273 - P280 - P301 + P310 + P330 - P302 + P352 + P312 - P305 + P351 + P338 - P314
Computed Properties
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
1
Rotatable Bond Count
10
Exact Mass
372.158752 g/mol
Monoisotopic Mass
372.158752 g/mol
Topological Polar Surface Area
17.8Ų
Heavy Atom Count
19
Formal Charge
0
Complexity
211
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| US-10413537-B2 | 6-(5-membered heteroaryl)isoquinolin-3-yl-(5-membered heteroaryl) carboxamides and preparation and use thereof | 2017-10-27 |
| US-2019125741-A1 | 6-(5-membered heteroaryl)isoquinolin-3-yl-(5-membered heteroaryl) carboxamides and preparation and use thereof | 2017-10-27 |
| US-2020155540-A1 | 6-(5-membered heteroaryl)isoquinolin-3-yl-(5-membered heteroaryl) carboxamides and preparation and use thereof | 2017-10-27 |
| WO-2019084496-A1 | 6- (HETEROARYL 5-CHAIN) ISOQUINOLIN-3-YL- (HETEROARYL 5-CHAIN) CARBOXAMIDES, PREPARATION AND USE | 2017-10-27 |
| US-10744128-B2 | 6-(5-membered heteroaryl)isoquinolin-3-yl-(5-membered heteroaryl) carboxamides and preparation and use thereof | 2017-10-27 |
| US-10604514-B2 | 6-(5-membered heteroaryl)isoquinolin-3-yl carboxamides and preparation and use thereof | 2017-10-19 |
| US-2019119263-A1 | 6-(5-membered heteroaryl)isoquinolin-3-yl carboxamides and preparation and use thereof | 2017-10-19 |
| WO-2019079626-A1 | 6- (HETEROARYL 5-CHAIN) ISOQUINOLIN-3-YL CARBOXAMIDES, THEIR PREPARATION AND THEIR USE | 2017-10-19 |
| US-2021024566-A1 | Nucleoside analogues for the treatment of parasitic infections | 2017-10-19 |
| US-11072628-B2 | Nucleoside analogues for the treatment of parasitic infections | 2017-10-19 |
Literatures
| PMID | Publication Date | Title | Journal |
|---|---|---|---|
| 16129675 | 2005-10-28 | Activation of membrane cholesterol by displacement from phospholipids | The Journal of biological chemistry |
| 5387 | 1976-03-01 | [Report on the 8th Annual Convention of the Deutsche Gesellschaft zum Studium der Fertilität und Sterilität Berlin, June 13-15, 1975] | Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete |
