2,2'-BIPYRIDINE-3,3'-DIOL
Product Information
Molecular Formula
C10H8N2O2
Molecular Weight
188.18
Description
2,2'-Bipyridine-3,3'-diol is an important compound in the biomedical field, promoting a variety of inorganic and organometallic reactions. It is used as a reagent in drug synthesis to generate therapeutic compounds that relieve cardiovascular diseases such as angina and hypertension.
Synonyms
[2,2'-BIPYRIDYL]-3,3'-DIOL; 2,2'-BIPYRIDYL-3,3DIOL; 2,2'-BIPYRIDINE-3,3'-DIOL; 2,2'-BIS(3-PYRIDINOL); 2-(3-HYDROXY-2-PYRIDYL)-3-PYRIDINOL; 3,3'-DIHYDROXY-2,2'-BIPYRIDINE
IUPAC Name
2-(3-hydroxypyridin-2-yl)pyridin-3-ol
SMILES
Oc1cccnc1-c2ncccc2O
InChI
InChI=1S/C10H8N2O2/c13-7-3-1-5-11-9(7)10-8(14)4-2-6-12-10/h1-6,13-14H
InChI Key
RJNRKZBHLCOHNM-UHFFFAOYSA-N
Melting Point
194-196 °C (lit.)
Purity
98%
Density
1.363 g/cm3
Safety Information
Hazards
H315 - H319 - H335
Precautionary Statement
P302 + P352 - P305 + P351 + P338
Signal Word
Warning
Computed Properties
XLogP3
0.8
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
4
Rotatable Bond Count
1
Exact Mass
188.058577502 g/mol
Monoisotopic Mass
188.058577502 g/mol
Topological Polar Surface Area
66.2Ų
Heavy Atom Count
14
Formal Charge
0
Complexity
169
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| CN-112978709-A | Carbon quantum dot precursor composition, carbon quantum dot and preparation method thereof | 2019-12-12 |
| US-2021061818-A1 | Bipyridine and bipyrimidine gold(iii) dithiocarbamate complexes and methods of treating cancer | 2019-08-28 |
| WO-2020116037-A1 | Polybutadiene, polybutadiene production method, polybutadiene composition, tire, and resin member | 2018-12-05 |
| US-2021171883-A1 | Antiviral wiper | 2018-08-29 |
| TW-202003734-A | Resin composition, laminate, semiconductor wafer with resin composition layer, mounting substrate for semiconductor with resin composition layer, and semiconductor device | 2018-04-26 |
| WO-2019208614-A1 | Resin composition, laminate, resin composition layer-attached semiconductor wafer, substrate for mounting resin composition layer-attached semiconductor, and semiconductor device | 2018-04-26 |
| EP-3786200-A1 | Resin composition, laminate, resin composition layer-attached semiconductor wafer, substrate for mounting resin composition layer-attached semiconductor, and semiconductor device | 2018-04-26 |
| KR-20210004971-A | Resin composition, laminate, semiconductor wafer with resin composition layer, semiconductor mounting substrate with resin composition layer, and semiconductor device | 2018-04-26 |
| JP-WO2019208614-A1 | Resin composition, laminate, semiconductor wafer with resin composition layer, semiconductor mounting substrate with resin composition layer, and semiconductor device | 2018-04-26 |
| US-2021277221-A1 | Resin composition, laminate, semiconductor wafer with resin composition layer, substrate for mounting semiconductor with resin composition layer and semiconductor device | 2018-04-26 |
Literatures
| PMID | Publication Date | Title | Journal |
|---|---|---|---|
| 22913628 | 2012-09-20 | Prototropism of [2,2'-bipyridyl]-3,3'-diol in albumin-SDS aggregates | The journal of physical chemistry. B |
| 22469101 | 2012-05-03 | (2,2'-bipyridyl)-3-3'-diol in nafion: stabilization of unusual ground and excited states | The journal of physical chemistry. B |
| 21214252 | 2011-02-10 | Modulation of ground- and excited-state dynamics of [2,2'-bipyridyl]-3,3'-diol by micelles | The journal of physical chemistry. B |
| 20957716 | 2010-12-03 | Modulating the photochemistry of bipyridylic compounds by symmetric substitutions | Chemphyschem : a European journal of chemical physics and physical chemistry |
| 20419715 | 2010-06-11 | Bipyridyl derivatives as photomemory devices: a comparative electronic-structure study | Chemistry (Weinheim an der Bergstrasse, Germany) |
| 19572684 | 2009-07-30 | Excited-state diproton transfer in [2,2'-bipyridyl]-3,3'-diol: the mechanism is sequential, not concerted | The journal of physical chemistry. A |
| 18759240 | 2008-10-06 | Study of the photochemical properties and conical intersections of [2,2'-bipyridyl]-3-amine-3'-ol | Chemphyschem : a European journal of chemical physics and physical chemistry |
| 18366045 | 2008-01-01 | Luminescent excited-state intramolecular proton-transfer (ESIPT) dyes based on 4-alkyne-functionalized [2,2'-bipyridine]-3,3'-diol dyes | Chemistry (Weinheim an der Bergstrasse, Germany) |
| 17655352 | 2007-08-23 | Investigating 2,2'-bipyridine-3,3'-diol as a microenvironment-sensitive probe: its binding to cyclodextrins and human serum albumin | The journal of physical chemistry. B |
| 17471481 | 2007-06-04 | A comparative study on the photochemistry of two bipyridyl derivatives: [2,2'-bipyridyl]-3,3'-diamine and [2,2'-bipyridyl]-3,3'-diol | Chemphyschem : a European journal of chemical physics and physical chemistry |
