2,2'-Diamino-4,4'-bithiazolyl
Product Information
Molecular Formula
C6H6N4S2
Molecular Weight
198.26
Description
2,2'-Diamino-4,4'-bithiazolyl is an immensely powerful substance widely adopted in the biomedical sector due to its remarkable anti-inflammatory attributes, serves as a pivotal agent for counteracting the detrimental effects associated with autoimmune disorders, notably including rheumatoid arthritis and multiple sclerosis. Evidencing a plethora of encouraging therapeutic possibilities, this unparalleled product serves as a formidable relief mechanism, skillfully ameliorating the distressing symptoms plaguing afflicted individuals.
Synonyms
2,2'-Diamino-4,4'-bis(1,3-thiazole)
4,4'-Bithiazole-2,2'-diamine
4,4'-Bithiazole-2,2'-diamine
IUPAC Name
4-(2-amino-1,3-thiazol-4-yl)-1,3-thiazol-2-amine
SMILES
C1=C(N=C(S1)N)C2=CSC(=N2)N
InChI
InChI=1S/C6H6N4S2/c7-5-9-3(1-11-5)4-2-12-6(8)10-4/h1-2H,(H2,7,9)(H2,8,10)
InChI Key
MRFMTBTUKQIBDI-UHFFFAOYSA-N
Boiling Point
499.8±20.0 °C(Predicted)
Melting Point
250 °C(dec.)
Purity
>98.0%(T)(HPLC)
Density
1.590±0.06 g/cm3(Predicted)
Appearance
White to Almost white powder to crystal
Storage
Store under inert gas
Refractive Index
1.62
Safety Information
Hazards
H315:
Causes skin irritation.
H319:
Causes serious eye irritation.
Causes skin irritation.
H319:
Causes serious eye irritation.
Precautionary Statement
P264:
Wash thoroughly after handling.
P280:
Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352:
IF ON SKIN:
Wash with plenty of soap and water.
P332+P313:
If skin irritation occurs:
Get medical advice/attention.
P337+P313:
If eye irritation persists:
Get medical advice/attention.
P362+P364:
Take off contaminated clothing. [As modified by IV ATP].
And wash it before reuse. [Added by IV ATP].
Wash thoroughly after handling.
P280:
Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352:
IF ON SKIN:
Wash with plenty of soap and water.
P332+P313:
If skin irritation occurs:
Get medical advice/attention.
P337+P313:
If eye irritation persists:
Get medical advice/attention.
P362+P364:
Take off contaminated clothing. [As modified by IV ATP].
And wash it before reuse. [Added by IV ATP].
Computed Properties
XLogP3
1
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
6
Rotatable Bond Count
1
Exact Mass
198.00338856 g/mol
Monoisotopic Mass
198.00338856 g/mol
Topological Polar Surface Area
134Ų
Heavy Atom Count
12
Formal Charge
0
Complexity
150
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| CN-113978053-A | Environment-friendly wear-resistant automobile carpet and preparation method thereof | 2021-12-14 |
| CN-109338343-B | Chemical silver plating solution and silver plating method | 2018-09-26 |
| CN-109134454-B | Preparation method and application of bithiazole azo compound | 2018-09-14 |
| JP-2019073681-A | Resin composition and use thereof | 2017-10-17 |
| EP-3412734-A1 | Dye compound, composition comprising the dye compound, and display device using the dye compound | 2017-06-08 |
| EP-3412734-B1 | Dye compound, composition comprising the dye compound, and display device using the dye compound | 2017-06-08 |
| KR-20180134441-A | Dye compound, composition comprising the same, and display device using the dye compound | 2017-06-08 |
| US-10442931-B2 | Dye compound, composition comprising dye compound, and display device using dye compound | 2017-06-08 |
| US-2018355179-A1 | Dye compound, composition comprising dye compound, and display device using dye compound | 2017-06-08 |
| JP-2017203058-A | Imide crosslinkable resin, transparent film and surface protective film | 2016-05-09 |
Literatures
| PMID | Publication Date | Title | Journal |
|---|---|---|---|
| 21669477 | 2011-09-01 | Synthesis and structure of new bicopper(II) complexes bridged by N-(2- aminopropyl)-N'-(2-oxidophenyl)oxamide: the effects of terminal ligands on structures, anticancer activities and DNA-binding properties | European journal of medicinal chemistry |
| 21754591 | 2011-06-01 | Aqua-(2,2'-diamino-4,4'-bi-1,3-thia-zole-κN,N)(pyridine-2,6-dicarboxyl-ato-κO,N,O)zinc tetra-hydrate | Acta crystallographica. Section E, Structure reports online |
| 21580550 | 2010-03-27 | [(E)-But-2-enoato-κO]chlorido(2,2'-diamino-4,4'-bi-1,3-thia-zole-κN,N)zinc(II) monohydrate | Acta crystallographica. Section E, Structure reports online |
| 21580275 | 2010-02-27 | Bis(μ-imino-diacetato)bis-[(2,2'-diamino-4,4'-bi-1,3-thia-zole)lead(II)] tetra-hydrate | Acta crystallographica. Section E, Structure reports online |
| 21583303 | 2009-07-29 | Bis(2,2'-diamino-4,4'-bi-1,3-thia-zole-κN,N)bis-(nitrato-κO)lead(II) dihydrate | Acta crystallographica. Section E, Structure reports online |
| 21583318 | 2009-07-01 | Dichlorido(2,9-dimethyl-4,7-diphenyl-1,10-phenanthroline-κN,N')mercury(II) acetonitrile hemisolvate | Acta crystallographica. Section E, Structure reports online |
| 21582740 | 2009-06-24 | (2,9-Dimethyl-4,7-diphenyl-1,10-phen-anthroline-κN,N')bis-(thio-cyanato-κS)mercury(II) | Acta crystallographica. Section E, Structure reports online |
| 21582094 | 2009-02-25 | (2'-Amino-4,4'-bi-1,3-thia-zol-2-aminium-κN,N')aqua-[citrato(4-)-κO,O',O'')chromium(III) dihydrate | Acta crystallographica. Section E, Structure reports online |
| 21582245 | 2009-02-25 | 2,2'-Diamino-4,4'-bi-1,3-thia-zolium bis-(3-nitro-benzoate) | Acta crystallographica. Section E, Structure reports online |
| 21582064 | 2009-02-18 | Tetra-aqua-(2,2'-diamino-4,4'-bi-1,3-thia-zole-κN,N)nickel(II) bis-(pyridine-2,6-dicarboxyl-ato-κO,N,O)nickel(II) trihydrate | Acta crystallographica. Section E, Structure reports online |
