2-(3,5-DIMETHOXY)-PHENYL-4,4,5,5-TETRAMETHYL-(1,3,2)-DIOXABOROLANE
Product Information
Molecular Formula
C14H21BO4
Molecular Weight
264.13
Description
2-(3,5-Dimethoxy)-phenyl-4,4,5,5-tetramethyl-(1,3,2)-dioxaborolane is a biomedicine product used in the drug development of certain diseases. It plays a crucial role as a pharmaceutical intermediate, assisting in the synthesis of various drugs targeting specific conditions. The compound's unique structure and properties make it valuable in drug discovery and development processes within the biomedical industry.
Synonyms
2-(3,5-DIMETHOXY)-PHENYL-4,4,5,5-TETRAMETHYL-(1,3,2)-DIOXABOROLANE; 3,5-DIMETHOXYPHENYLBORONIC ACID, PINACOL ESTER
IUPAC Name
2-(3,5-dimethoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
SMILES
B1(OC(C(O1)(C)C)(C)C)C2=CC(=CC(=C2)OC)OC
InChI
InChI=1S/C14H21BO4/c1-13(2)14(3,4)19-15(18-13)10-7-11(16-5)9-12(8-10)17-6/h7-9H,1-6H3
InChI Key
CZYHRTIJLUONKY-UHFFFAOYSA-N
Melting Point
90-94 °C (lit.)
Purity
96%
Appearance
White powder to off-white powder and/or chunks
Computed Properties
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
4
Rotatable Bond Count
3
Exact Mass
264.1532893 g/mol
Monoisotopic Mass
264.1532893 g/mol
Topological Polar Surface Area
36.9Ų
Heavy Atom Count
19
Formal Charge
0
Complexity
291
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| WO-2021262684-A1 | METHODS AND COMPOUNDS FOR RESTORING MUTANT p53 FUNCTION | 2020-06-22 |
| US-2021171535-A1 | Tricyclic heterocycles as fgfr inhibitors | 2019-12-04 |
| WO-2021113479-A1 | Tricyclic heterocycles as fgfr inhibitors | 2019-12-04 |
| EA-037563-B1 | NEW (HETERO) ARYL-SUBSTITUTED PIPERIDINYL DERIVATIVES, METHOD FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | 2016-12-28 |
| EP-3486244-A1 | New compound having fgfr inhibitory activity and preparation and application thereof | 2016-06-16 |
| JP-2019521992-A | Novel compounds having FGFR inhibitory activity and their production and use | 2016-06-16 |
| US-2019367520-A1 | New compound having fgfr inhibitory activity and preparation and application thereof | 2016-06-16 |
| WO-2017215485-A1 | New compound having fgfr inhibitory activity and preparation and application thereof | 2016-06-16 |
| CA-3027008-A1 | (hetero)aryl-substituted-piperidinyl derivatives, a process for their preparation and pharmaceutical compositions containing them | 2016-06-10 |
| CA-3027014-A1 | Piperidinyl derivatives, a process for their preparation and pharmaceutical compositions containing them | 2016-06-10 |
