2-Fluoro-3-(tributylstannyl)pyridine
Product Information
Molecular Formula
C17H30FNSn
Molecular Weight
386.12
Description
2-Fluoro-3-(tributylstannyl)pyridine is a specialized organotin compound frequently in medicinal chemistry. Principally, it's used to facilitate palladium-catalyzed processes like Stille coupling, instrumental in the synthesis of various pharmaceuticals, including anti-cancer and anti-viral drugs.
Synonyms
Tributyl-(2-fluoropyridin-3-yl)stannane; Pyridine, 2-fluoro-3-(tributylstannyl)-; 2-fluoro-3-tributylstannylpyridine; 2-fluoro-3-(tributylstannanyl)pyridine; 2-Fluoro-3-(tributylstannyl)pyridine, 97%;
IUPAC Name
tributyl-(2-fluoropyridin-3-yl)stannane
SMILES
CCCC[Sn](CCCC)(CCCC)C1=C(N=CC=C1)F
InChI
InChI=1S/C5H3FN.3C4H9.Sn/c6-5-3-1-2-4-7-53*1-3-4-2/h1-2,4H3*1,3-4H2,2H3
InChI Key
UEIDBUBBTLTCOP-NACNSUOOAP
Flash Point
>230 °F
Purity
96%
Density
1.176 g/mL at 25 °C
Refractive Index
n20/D 1.508
Safety Information
Hazards
H301-H312-H315-H319-H372-H410
Precautionary Statement
P273-P280-P301 + P310-P305 + P351 + P338-P314-P501
Computed Properties
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
2
Rotatable Bond Count
10
Exact Mass
387.138431 g/mol
Monoisotopic Mass
387.138431 g/mol
Topological Polar Surface Area
12.9Ų
Heavy Atom Count
20
Formal Charge
0
Complexity
225
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| WO-2014022377-A1 | Membranes and coatings made from mixtures including ionic liquids having silicon-bonded hydrolyzable groups | 2012-07-30 |
| CA-2837146-A1 | Benzocycloheptene acetic acids | 2011-06-06 |
| EP-2718264-A1 | Benzocycloheptene acetic acids | 2011-06-06 |
| EP-2718264-B1 | Benzocycloheptene acetic acids | 2011-06-06 |
| JP-2014522407-A | Benzocycloheptene acetic acid | 2011-06-06 |
| MX-2013013849-A | ACIDS BENZOCICLOHEPTENO ACETICOS. | 2011-06-06 |
| US-2012309796-A1 | Benzocycloheptene acetic acids | 2011-06-06 |
| WO-2012168162-A1 | Benzocycloheptene acetic acids | 2011-06-06 |
| EP-2579717-A2 | Positive allosteric modulators of mglur2 | 2010-06-09 |
| US-2013210768-A1 | Positive allosteric modulators of mglur2 | 2010-06-09 |
