2-Hydroxy-4'-(2-hydroxyethoxy)-2-methylpropiophenone
Product Information
Molecular Formula
C12H16O4
Molecular Weight
224.25
Description
4'-Hydroxyacetophenone has been used as ketone component in the preparation of 1-aryl-3-phenethylamino-1-propanone hydrochlorides, potential cytotoxic agents, via Mannich reactions.
Synonyms
2-hydroxy-1-[4-(2-hydroxyethoxy)phenyl]-2-methyl-1-propanone; 2-hydroxy-1-[4-(2-hydroxyethoxy)phenyl]-2-methylpropan-1-one
IUPAC Name
2-hydroxy-1-[4-(2-hydroxyethoxy)phenyl]-2-methylpropan-1-one
SMILES
CC(C)(C(=O)C1=CC=C(C=C1)OCCO)O
InChI
InChI=1S/C12H16O4/c1-12(2,15)11(14)9-3-5-10(6-4-9)16-8-7-13/h3-6,13,15H,7-8H2,1-2H3
InChI Key
GJKGAPPUXSSCFI-UHFFFAOYSA-N
Boiling Point
175 °C / 15 mmHg (lit.)
Melting Point
91 °C
Flash Point
327.2 °F
Purity
98 %
Density
1.183 g/cm3
Appearance
White to light yellow powder to crystal
Storage
Keep in dark place, Sealed in dry, Room Temperature
Refractive Index
n20/D 1.475 (lit.)
LogP
1.01130
Safety Information
Hazards
H411
Precautionary Statement
P273
Computed Properties
XLogP3
0.8
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
4
Rotatable Bond Count
5
Exact Mass
224.10485899 g/mol
Monoisotopic Mass
224.10485899 g/mol
Topological Polar Surface Area
66.8Ų
Heavy Atom Count
16
Formal Charge
0
Complexity
229
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| CN-114082310-A | Roll type membrane element and preparation method and application thereof | 2022-01-20 |
| CN-114058040-A | Preparation method of 3D hydrogel for cell amplification culture, product and application thereof | 2021-12-28 |
| CN-114058210-A | Water-based photo-curing ink composition, and preparation method and application thereof | 2021-12-21 |
| CN-113980189-A | Polyester acrylic acid weather-resistant pressure-sensitive adhesive and preparation method thereof | 2021-12-17 |
| CN-114177369-A | Blocking anti-adhesion membrane material and preparation method thereof | 2021-12-17 |
| CN-114149717-A | Hydrogel function modified coating and preparation method thereof | 2021-12-16 |
| JP-2022040133-A | A photosensitive coloring composition for a color filter for a solid-state image sensor, a color filter, and a solid-state image sensor using the same. | 2021-12-15 |
| CN-114163550-A | Multifunctional macromolecular photoinitiator and preparation method thereof | 2021-12-14 |
| CN-114164201-A | Preparation method of immobilized cellulase with temperature-pH dual responsiveness | 2021-12-13 |
| CN-113968936-A | Tough chitosan hydrogel and preparation method and application thereof | 2021-12-09 |
Literatures
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|---|---|---|---|
| 22767528 | 2012-07-16 | Systematic studies of UV stability and photopolymerization efficiency of DNA-based nanomaterials | Chemphyschem : a European journal of chemical physics and physical chemistry |
| 22215075 | 2011-12-16 | Tracking hypoxic signaling within encapsulated cell aggregates | Journal of visualized experiments : JoVE |
| 21871915 | 2011-12-01 | Photocrosslinkable biodegradable responsive hydrogels as drug delivery systems | International journal of biological macromolecules |
| 21232640 | 2011-05-01 | Resorbable elastomeric networks prepared by photocrosslinking of high-molecular-weight poly(trimethylene carbonate) with photoinitiators and poly(trimethylene carbonate) macromers as crosslinking aids | Acta biomaterialia |
| 20565511 | 2010-03-01 | Unusual allergic contact dermatitis produced by a transcutaneous electrical nerve stimulator | Contact dermatitis |
| 19783300 | 2009-12-01 | Photoinitiated polymerization of PEG-diacrylate with lithium phenyl-2,4,6-trimethylbenzoylphosphinate: polymerization rate and cytocompatibility | Biomaterials |
| 18690661 | 2009-10-01 | Cytocompatibility studies of an in situ photopolymerized thermoresponsive hydrogel nanoparticle system using human aortic smooth muscle cells | Journal of biomedical materials research. Part A |
| 18597016 | 2008-07-21 | Direct observation of f-pair magnetic field effects and time-dependence of radical pair composition using rapidly switched magnetic fields and time-resolved infrared methods | Physical chemistry chemical physics : PCCP |
| 18065171 | 2008-03-20 | Development of a new photocrosslinkable biodegradable bioadhesive | International journal of pharmaceutics |
| 18214758 | 2008-01-01 | UV cross-linked dextran methacrylate--concanavalin A methacrylamide gel materials for self-regulated insulin delivery | Drug development and industrial pharmacy |
