2-Methyl-2H-indazole-5-boronic acid pinacol ester
Product Information
Molecular Formula
C14H19BN2O2
Molecular Weight
258.13
Description
2-Methyl-2H-indazole-5-boronic acid pinacol ester is a pivotal intermediary in the synthetic process of pharmacological compounds. This biomedical entity manifests inherent promise in the formulation of remedies targeting an array of afflictions including neoplasms, hyperglycemia, and inflammatory conditions. The multifaceted essence it embodies substantiates its profound impact on the propelling frontiers of biomedical research and the expedition of therapeutic innovation.
Synonyms
2-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2H-indazole; 2-METHYLINDAZOLE-5-BORONIC ACID PINACOL ESTER; 2-methyl-5-(tetramethyl-1,3,2-dioxaborolan-2-yl)-2H-indazole; 2-Methyl-2H-indazole-5-boronic acid pinacol ester; 2-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)indazole; 2-Methyl-2H-indazole-5-boronic acid,pinacol ester; 2-Methyl-2H-indazole-5-boronic acid pinacol ester; 2-methyl-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-2H-indazole
IUPAC Name
2-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)indazole
SMILES
B1(OC(C(O1)(C)C)(C)C)C2=CC3=CN(N=C3C=C2)C
InChI
InChI=1S/C14H19BN2O2/c1-13(2)14(3,4)19-15(18-13)11-6-7-12-10(8-11)9-17(5)16-12/h6-9H,1-5H3
InChI Key
PFZWGNKMAGHYBG-UHFFFAOYAN
Flash Point
Not applicable
Purity
97.0%
Computed Properties
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
3
Rotatable Bond Count
1
Exact Mass
258.1539580 g/mol
Monoisotopic Mass
258.1539580 g/mol
Topological Polar Surface Area
36.3Ų
Heavy Atom Count
19
Formal Charge
0
Complexity
345
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| WO-2021216951-A1 | Condensed substituted hydropyrroles as antagonists of the muscarinic acetylcholine receptor m4 | 2020-04-24 |
| WO-2021207554-A1 | Compounds and methods for modulating splicing | 2020-04-08 |
| WO-2021143729-A1 | Compound, composition and functional molecule with multi-target inhibiting effect and use thereof | 2020-01-15 |
| WO-2021139775-A1 | Pyridone compound and application | 2020-01-10 |
| WO-2021129621-A1 | Pyrazole compounds | 2019-12-23 |
| WO-2021119254-A1 | Antagonists of the muscarinic acetylcholine receptor m4 | 2019-12-10 |
| WO-2020243376-A1 | Heterobicyclic inhibitors of mat2a and methods of use for treating cancer | 2019-05-31 |
| AU-2020284018-A1 | Heterobicyclic inhibitors of MAT2A and methods of use for treating cancer | 2019-05-31 |
| WO-2020022323-A1 | Heterobicyclic compounds for inhibiting the activity of shp2 | 2018-07-24 |
| TW-202019921-A | Heterobicyclic compounds for inhibiting SHP2 activity | 2018-07-24 |
