2-methylthiazole-5-boronic acid pinacol ester
Product Information
Molecular Formula
C10H16BNO2S
Molecular Weight
225.12
Description
As a small biological molecule, 2-methylthiazole-5-boronic acid pinacol ester can be used to develop therapeutic drugs for diseases such as cancer and inflammation.
Synonyms
2-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiazole; 2-Methylthiazole-5-boronic acid pinacol ester; 2-Methylthiazole-5-boronic acid, pinacol ester; 2-METHYL-5-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)-1,3-THIAZOLE; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-methyl-1,3-thiazole; 2-methyl-5-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1,3-thiazole; 2-methylthiazole 5-boronic acid pinacol ester
IUPAC Name
2-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,3-thiazole
SMILES
B1(OC(C(O1)(C)C)(C)C)C2=CN=C(S2)C
InChI
InChI=1S/C10H16BNO2S/c1-7-12-6-8(15-7)11-13-9(2,3)10(4,5)14-11/h6H,1-5H3
InChI Key
QXMZPGMBRRZCDV-UHFFFAOYSA-N
Flash Point
Not applicable
Computed Properties
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
4
Rotatable Bond Count
1
Exact Mass
225.0994801 g/mol
Monoisotopic Mass
225.0994801 g/mol
Topological Polar Surface Area
59.6Ų
Heavy Atom Count
15
Formal Charge
0
Complexity
244
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| WO-2022023339-A1 | Aryl substituted pyrrolo-pyridinones and therapeutic uses thereof | 2020-07-29 |
| WO-2022003575-A1 | Her2 mutation inhibitors | 2020-06-30 |
| WO-2021168197-A1 | Bifunctional degraders of interleukin-1 receptor-associated kinases and therapeutic use thereof | 2020-02-19 |
| CN-111892592-A | JAK kinase inhibitors and uses thereof | 2019-08-06 |
| US-2020347053-A1 | Substituted pyrrolopyridines as jak inhibitors | 2019-05-02 |
| WO-2020223728-A1 | Substituted pyrrolopyridines as jak inhibitors | 2019-05-02 |
| AU-2020265828-A1 | Substituted pyrrolopyridines as JAK inhibitors | 2019-05-02 |
| CN-113727975-A | Substituted pyrrolopyridines as JAK inhibitors | 2019-05-02 |
| EP-3962897-A1 | Substituted pyrrolopyridines as jak inhibitors | 2019-05-02 |
| KR-20220004726-A | Substituted pyrrolopyridines as JAK inhibitors | 2019-05-02 |
